- Transplantation: Methods and Outcomes
- Cardiomyopathy and Myosin Studies
- Muscle Physiology and Disorders
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Congenital Heart Disease Studies
- Cardiovascular Effects of Exercise
- Nuclear Structure and Function
- Cardiac Structural Anomalies and Repair
- RNA Interference and Gene Delivery
- Viral Infections and Immunology Research
- Mitochondrial Function and Pathology
- Respiratory viral infections research
- Tissue Engineering and Regenerative Medicine
- Pneumonia and Respiratory Infections
- Glycogen Storage Diseases and Myoclonus
- Cardiac pacing and defibrillation studies
- Advanced MRI Techniques and Applications
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- Cardiac Imaging and Diagnostics
- Antibiotics Pharmacokinetics and Efficacy
- Coronary Artery Anomalies
- Prosthetics and Rehabilitation Robotics
Nationwide Children's Hospital
2020-2025
The Ohio State University
2020-2024
University of Canterbury
2024
ABSTRACT Background Short‐term outcomes following heart transplantation in children have improved, but comparable improvements long‐term survival continues to barriers. We sought investigate and identify protective risk factors associated with children. Methods The Pediatric Heart Transplant Society (PHTS) database was queried for transplant recipients from 1993 2010 who were ≤ 10 years of age at time transplant. Patients conditional graft > 3 ≥ analyzed. Survival time‐to‐event compared...
Abstract Introduction: Duchenne muscular dystrophy is a devastating neuromuscular disorder characterized by the loss of dystrophin, inevitably leading to cardiomyopathy. Despite publications on prophylaxis and treatment with cardiac medications mitigate cardiomyopathy progression, gaps remain in specifics medication initiation optimization. Method: This document an expert opinion statement, addressing critical gap care for dystrophy. It provides thorough recommendations titration based...
Abstract Duchenne muscular dystrophy (DMD) is the most common form of childhood resulting in progressive muscle wasting and weakness. With advancements respiratory care use glucocorticoids, cardiomyopathy has surpassed compromise as leading cause morbidity mortality this patient population. As remains a relative contraindication to heart transplantation, end‐stage failure management represents major therapeutic challenge. Long‐term left ventricular assist device (LVAD) therapy emerged...
Arrhythmogenic cardiomyopathy (ACM) is an inherited associated with fibrofatty tissue replacement of the ventricular tissue. The disease can cause dysfunction and arrhythmias increase risk sudden cardiac death. This have variable clinical presentations, especially in pediatric young adult populations. In this report, we describe case 18-year-old female myocarditis as initial presentation ACM. She presented following a resuscitated arrest due to arrhythmia. On arrival, myocardial edema...
Objectives Vaccinations are an important preventative measure in reducing the spread of infectious diseases worldwide. However, concerns undervaccination during childhood have become increasingly common. The current study aims to investigate changes attitudes towards vaccinations prior COVID-19 pandemic using a national sample from New Zealand. Design Age-based, period-based, and cohort-based were assessed cohort-sequential latent growth modelling 11 overlapping birth cohorts, which spanned...
Background : Highly sensitized pediatric patients awaiting heart transplantation experience longer wait times and thus higher waitlist mortality. Similarly, children less than 2 years of age have increased mortality when compared to their older peers. To improve the likelihood successful in these patients, various strategies been utilized, including peri-operative plasmapheresis. However, limited data exists comparing plasmapheresis techniques for antibody reduction. This study’s aim was...
Introduction: Despite improvements in pediatric heart transplant outcomes, respiratory syncytial virus (RSV) and vaccine preventable infections (R/VPI) are a major cause of morbidity hospital resource use. The frequency risk factors for hospitalizations due to R/VPI recipients unknown. Methods: Patients ≤18 years who underwent transplantation at hospitals contributing the Pediatric Health Information System database from 9/2003 12/2018 were identified. hospitalization subsequent through...