A5078855110- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Congenital Heart Disease Studies
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Muscle Physiology and Disorders
- Transplantation: Methods and Outcomes
- Central Venous Catheters and Hemodialysis
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Melanoma and MAPK Pathways
- Neurological disorders and treatments
- Nuclear Structure and Function
- Cardiac Valve Diseases and Treatments
- Renal Transplantation Outcomes and Treatments
- Vascular anomalies and interventions
- Computational Drug Discovery Methods
- Viral Infections and Immunology Research
- Advanced Biosensing Techniques and Applications
- Hemodynamic Monitoring and Therapy
Nationwide Children's Hospital
2016-2025
The Ohio State University
2011-2023
The Ohio State University Wexner Medical Center
2019-2022
Children's Hospital at Montefiore
2017
Albert Einstein College of Medicine
2017
Medtronic (Ireland)
2017
Montefiore Medical Center
2017
Biotronik (Switzerland)
2017
Boston Scientific (United States)
2017
Northwestern University
1992-2015
<h3>Importance</h3> Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially lethal genetic arrhythmia syndrome characterized by with physical or emotional stress, for which current therapy β-blockers incompletely effective. Flecainide acetate directly suppresses sarcoplasmic reticulum calcium release—the cellular mechanism responsible triggering arrhythmias in CPVT—but has never been assessed prospectively. <h3>Objective</h3> To determine whether flecainide dosed to...
Background— Some patients with hypertrophic cardiomyopathy (HCM) or left ventricular hypertrophy also present skeletal myopathy and Wolff-Parkinson-White (WPW) syndrome; mutations in the gene encoding lysosome-associated protein-2 (LAMP-2) have been identified these patients, suggesting that some of Danon disease. In this study we investigated frequency LAMP2 an unselected pediatric HCM population. Methods Results— was amplified from genomic DNA isolated peripheral lymphocytes 50 diagnosed...
To determine the sequela of right ventricular pacing in children with congenital complete atrioventricular block.Pacing is a well-accepted therapy for patients block. The long-term this population has not been well described.We performed cohort study on all block who underwent pacemaker implantation at our institution from 1972 to 2004. Patients associated heart disease or dysfunction prior were excluded.A total 63 included study. median age was 6.5 years, an average follow-up 9.9 years....
Background: Because of venous occlusion, intracardiac shunting, previous surgery, or small size placement implantable cardioverter‐defibrillator (ICD) leads may not be possible using traditional methods. The purpose this study was to evaluate and describe innovative methods placing ICD leads. Methods: records all patients undergoing implantation at our institution were reviewed identify with nontraditional lead placement. Indications for ICD, method coil placement, defibrillation thresholds,...
Transcatheter Leadless Pacemakers (TLP) are a safe and effective option for adults with pacing indications. These devices may be an alternative in pediatric patients congenital heart disease whom repeated sternotomies, thoracotomies, or transvenous systems unfavorable. However, exemption of children from clinical trials has created uncertainty over the indications, efficacy, safety TLP population. The objectives this study to evaluate procedural characteristics, electrical performance,...