- biodegradable polymer synthesis and properties
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Hepatitis B Virus Studies
- Microplastics and Plastic Pollution
- Hepatitis C virus research
- SARS-CoV-2 detection and testing
- Animal Genetics and Reproduction
- COVID-19 Clinical Research Studies
- Biopolymer Synthesis and Applications
- Cancer Risks and Factors
- Bacteriophages and microbial interactions
- Liver Disease Diagnosis and Treatment
- Biosensors and Analytical Detection
- Plant Taxonomy and Phylogenetics
- Plant and Fungal Species Descriptions
- Bacterial biofilms and quorum sensing
- Nutritional Studies and Diet
- Colorectal Cancer Screening and Detection
- Viral Infectious Diseases and Gene Expression in Insects
- Plant responses to water stress
- Animal Nutrition and Physiology
NORCE Norwegian Research Centre
2023-2025
London Research and Development Centre
2021-2023
Western University
2021-2023
Agriculture and Agri-Food Canada
2021-2023
Can Tho University
2023
University of Waterloo
2015-2021
Temple University Health System
2017
Fox Chase Cancer Center
2017
Korea Advanced Institute of Science and Technology
2009
Intelligent Synthetic Biology Center
2009
Wastewater treatment plants (WWTPs) may serve as hotspots for pathogens and promote antimicrobial resistance (AMR). Plastic debris in wastewater could further contribute to AMR dissemination. The aim of this study was investigate the impact various microplastic types on bacterial communities gene abundance that were obtained from two WWTPs, one Tromsø, Norway, other Potchefstroom, South Africa. microcosm experiments designed follows: Five manufactured pellet used testing, rock aggregate...
InfoMetricsFiguresRef. Environmental Science & TechnologyASAPArticle This publication is Open Access under the license indicated. Learn More CiteCitationCitation and abstractCitation referencesMore citation options ShareShare onFacebookX (Twitter)WeChatLinkedInRedditEmailJump toExpandCollapse ViewpointJanuary 28, 2025Strengthening Policy Relevance of Wastewater-Based Surveillance for Antimicrobial ResistanceClick to copy article linkArticle link copied!Sheena Conforti*Sheena ConfortiEawag,...
Using livestock manure for fertilization can entrain antibiotic-resistant bacteria into soil. Manure on some dairy farms is anaerobically digested before being land applied.
Abstract While poly(3-hydroxybutyrate- co -3-hydroxyvalerate) [P(3HB- -3HV)] is a biodegradable commodity plastic with broad applications, its microbial synthesis hindered by high production costs primarily associated the supplementation of related carbon substrates (e.g. propionate or valerate). Here we report construction engineered Escherichia coli strains for direct P(3HB- -3HV) from an unrelated source glucose glycerol). First, E. strain activated sleeping beauty mutase (Sbm) operon was...
To evaluate the effectiveness of a community-based liver cancer prevention program on hepatitis B virus (HBV) screening among low-income, underserved Vietnamese Americans at high risk.We conducted cluster randomized trial involving 36 organizations and 2337 participants in Pennsylvania, New Jersey, York City between 2009 2014. We randomly assigned 18 to multilevel HBV intervention (n = 1131). remaining general education 1206), which included information about HBV-related prevention. assessed...
This study demonstrates that novel polymer production can be achieved by introducing pTAM, a broad-host-range plasmid expressing codon-optimized genes encoding Clostridium propionicum propionate CoA transferase (PctCp, Pct532) and modified Pseudomonas sp. MBEL 6-19 polyhydroxyalkanoate (PHA) synthase 1 (PhaC1Ps6-19, PhaC1400), into phaC mutant strains of the native producers Sinorhizobium meliloti putida. Both phenotypic analysis gas chromatography indicated synthesis accumulation...
Economically competitive commercial production of biodegradable bioplastics with desirable properties is an important goal. In this study, we demonstrate the use chromosome engineering alternative bacterial host, Sinorhizobium meliloti, for copolymer, poly(lactate-co-3-hydroxybutyrate). Codon-optimized genes 2 previously engineered enzymes, Clostridium propionicum propionate CoA transferase (Pct532Cp) and Pseudomonas sp. strain MBEL 6-19 polyhydroxyalkanoate (PHA) synthase 1...
Enterococci, commonly found in the normal intestinal flora of humans and animals, have emerged as an important human pathogen. A total 184 isolates (88 2015 96 2016) were collected from 46 flocks. Two predominant enterococcus species identified: Enterococcus faecalis (59%) faecium (~39%). Resistance to penicillin was significantly decreased overall enterococci community, while it remained unchanged multi-class resistant (MCR) community. We identified emeA efrAB genes, which encode efflux...
<title>Abstract</title> <bold>Background</bold> Coronavirus disease 2019 (COVID-19) pandemic constituted the largest global health crisis in recent generations and led to economic fallout. It may also have disrupted pattern of antimicrobial use (AMU) which subsequently affected development resistance (AMR). The AMR remains a grave human concern. This study aimed evaluate impact COVID-19 on AMU Nordics. <bold>Methods</bold> Nordic data (2017-2022) were extracted from national annual reports...
Background and Objective: Dimocarpus longan has been known widely due to its many nutritional values for human health.Therefore, this study aimed evaluate genetic diversity in the matK gene of D. varieties Mekong Delta.Materials Methods: Eleven were extracted by modified CTAB procedure amplified matK-4600/trnK-2R tamF/tamR primers.The DNA sequences treated BioEdit 7.0, MEGA 11, Geneious Denovo, ClustalW, NCBI/BLAST tool compared with longan-NC̲037447.1 on NCBI.The phylogenetic tree was...
The goal of this study was to (a) determine the minimum selection concentrations tetracycline family antibiotics necessary maintain plasmids carrying tetracycline-resistant genes and (b) correlate these results environmental hotspot reported in previous studies. This used two (pT295A pT413A) originating from dairy manure a surrogate Escherichia coli host CV601. tested nutrient-rich medium were determined as follows: 0.1 mg/L for oxytetracycline, 0.45 chlortetracycline, 0.13-0.25...
Abstract Introduction: Asian Americans is a Hepatitis B (HBV) disparity population who only account for 7% of the US but experience nearly 60% burden chronic HBV, which associated with 75% hepatocellular carcinoma (HCC). Adherence to HBV medication guideline practical approach preventing liver cancer. However, limited studies have been conducted on promoting adherence among underserved American patients. Methods: This study utilized 18-month follow-up data from randomized controlled clinical...