Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa used as a selection criterion.Transtympanic insertion treatment option for MD has been reported but its results have controversial. So far, no investigations in carried out.Twenty-two unilateral who were intractable to medical and had received tube....

The aim of this study was to analyze the demographic data pertaining and seasonal variation in specific vestibular disorders ear, nose, throat (ENT) practices Germany based on from a representative nationwide practice database.The sample included patients 116 ENT who received an initial diagnosis (ICD-10 code) Meniere's disease (MD, H81.0), benign paroxysmal positioning vertigo (BPPV, H81.1), or neuronitis (VN, H81.2) between January 2014 December 2016. Collected parameters age, sex, month...

The aim of this study was to analyze the prevalence dizziness- and vertigo-related diagnoses in ear, nose, throat (ENT) practices Germany associated demographic characteristics based on data from a representative nationwide practice database.The sample included patients 138 ENT who received vertigorelated (ICD-10 code) between January 2012 December 2015. Collected parameters age, sex, insurance status, prescribed medication (anatomical therapeutic chemical [ATC] class), referrals other...

Introduction: While there is an increasing demand for minimally invasive operative techniques in Ear, Nose and Throat surgery, these operations are difficult to learn junior doctors demanding supervise experienced surgeons. The motivation this study was integrate high-definition (HD) stereoscopic video monitoring microscopic surgery order facilitate teaching interaction between senior surgeon. Material methods: We attached a 1280x1024 HD stereo camera (TrueVisionSystems^TM Inc.,...

The aim of the present study was to provide an insight into medical treatment practices among patients with chronic rhinosinusitis (CRS) in Germany. An investigation ICD codes and ATC classes CRS general otolaryngology offices Germany should reveal prevalent behaviors German physicians.The used data from Disease Analyzer database (IQVIA). sample included 940 (GP) 106 (ENT) who were coded as having sinusitis (ICD-10: J32) or nasal polyps J33) 2015 (index date). primary outcome measures number...

The aim of this study was to determine the incidence inner ear involvement in various forms acute otitis media (AOM) ear, nose, and throat (ENT) practices Germany.Patients who had been diagnosed with AOM years 2010 2017 were enrolled from a nationwide, representative practice database (Disease Analyzer, IQVIA). In these patients, simultaneous or subsequent disorders (IED) determined within 7 days 12 months date an diagnosis.A total 286 186 patients enrolled. most frequent diagnoses...

The aim of the study was to investigate relationship between presence a hearing aid (HA) and occurrence various disorders external ear, using data from nose, throat (ENT) practices in Germany nationwide, representative practice database.In period 2012 2016, incidences ear (ICD-10 groups H60 H61) patients with HA prescriptions were compared retrospectively control group without (1:1 matching).A total 20,127 controls. highest 12-month (HA vs. controls) determined for "Impacted cerumen" (H61.2)...

Introduction: The master plan for innovative medical education established at RWTH Aachen Medical Faculty helped to set up an inter-disciplinary, interactive teaching environment undergraduate students during their clinical course. This study presents our first experience with microsurgery by means of highdefinition stereo video monitoring. Material and methods: A plastic model created ear inspection a handheld otoscope was modified exchangeable membrane resembling eardrum plus the human...

In the outpatient setting in Germany, patients with rhinosinusitis usually present at general practices (GP) or ear, nose, and throat (ENT) for initial diagnosis treatment.The aim of this study was to analyze referral patterns GPs ENT respect existing recommendations.The sample included from 940 GP 106 Disease Analyzer database (IQVIA) who received an acute sinusitis (AS) chronic (CS), nasal polyp (NP) 2015.The total numbers versus were 24,648 12,095 (AS), 26,768 19,826 516 1773 (NP)....

Investigating the expression and prognostic significance of adenovirus receptors DSG-2, CXADR CD46 in head neck cancer.

ABSTRACT Objectives Epithelial cells are an important part of the pathomechanism in chronic rhinosinusitis with nasal polyps. It is therefore essential to establish a robust method for isolation and culture epithelial from polyps enable further research. In this study, feasibility outgrowth technique was evaluated. Methods The performed isolate cells. Proliferation evaluated up 3rd passage. were identified differentiation proliferation using flow cytometry anti-cytokeratin, anti-p63,...

Epithelial cells may play an important role in the pathologic process of chronic rhinosinusitis with nasal polyps. Therefore, providing epithelial from a biobank could greatly contribute to further research. In present work, isolation long-term cryopreserved tissue is demonstrated. Polyp tissues were commercially available freezing medium dimethyl sulfoxide and stored liquid nitrogen. The outgrowth proliferation evaluated compared that fresh tissue. Flow cytometric analysis anti-cytokeratin,...

Abstract Background Epithelial cells are an important part of the pathomechanism in chronic rhinosinusitis with nasal polyps. It is therefore essential to establish a robust method for isolation and culture epithelial from polyps enable further research. In this study, feasibility outgrowth technique was evaluated. Results Using technique, could be isolated all tissue samples. Isolated showed proliferation rate approximately 7- 23-fold every 6 days up 3rd passage. Over 97% were shown...

Background Pain is a major symptom of chronic rhinosinusitis (CRS). It mainly associated with CRS without nasal polyps (CRSsNP) and has impact in the decision to move on surgery. Patients (CRSwNP) are characterized by trigeminal hypoesthesia suffer from less pain. The aim this study was investigate whether induces alterations peripheral nociceptive neurons, focusing quantitative changes. Methods Sinus mucosa inferior turbinate (IT) samples were obtained patients CRS, IT tissue healthy served...

Zusammenfassung Die Anzahl der gemeldeten Syphilis-Fälle steigt seit Jahren an. sexuell übertragbare Erkrankung wird durch die Spirochäte Treponema pallidum Subspezies verursacht und verläuft hierbei in verschiedenen Stadien. In allen Stadien können Symptome im HNO-Bereich auftreten. Hierdurch ist bei passenden Symptomen eine Syphilis-Infektion als Differenzialdiagnose vom HNO-Arzt stets zu bedenken. So zunehmendem oralem Geschlechtsverkehr Primäraffekt/harter Schanker zunehmend häufig...

Introduction In 2019, metamizole was the second most commonly prescribed drug in Germany despite known risk of agranulocytosis and strict indication.

Objectives: To evaluate the usefulness for online computer-based stereoscopic video monitoring teaching junior surgeons define which operative procedures in otorhinolaryngology benefit most form surgical using monitors. Methods: This clinical study was conducted from January 2008 until 2010. 95 (12 cochlear implantations, 3 stapedotomies, 28 tympanoplasties, 17 endonasal sinus surgeries and 35 endolaryngeal procedures) were under addition to (55) or replacing binoculars (40). In 78...