Rakesh Mandal

ORCID: 0000-0002-4591-6149
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About
Contact & Profiles
Research Areas
  • Research on Leishmaniasis Studies
  • Insect Pest Control Strategies
  • Viral Infections and Vectors
  • Chronic Myeloid Leukemia Treatments
  • Bladder and Urothelial Cancer Treatments
  • Air Quality and Health Impacts
  • Multiple and Secondary Primary Cancers
  • Insect and Pesticide Research
  • Vector-borne infectious diseases
  • Climate Change and Health Impacts
  • Cancer Risks and Factors
  • Agricultural Practices and Plant Genetics
  • Neurobiology and Insect Physiology Research
  • Agricultural Economics and Practices
  • Lung Cancer Research Studies
  • Mosquito-borne diseases and control
  • Global Health and Epidemiology
  • Agriculture and Biological Studies
  • Autopsy Techniques and Outcomes
  • Environmental and Biological Research in Conflict Zones
  • Plant Surface Properties and Treatments
  • Potassium and Related Disorders
  • Animal Vocal Communication and Behavior
  • Gender, Education, and Development Issues
  • Sleep and Wakefulness Research

Rajendra Memorial Research Institute of Medical Sciences
2012-2022

Ministry of Health and Family Welfare
2020

University of Wisconsin–Madison
2011-2020

Biratnagar Eye Hospital
2018

Indian Council of Medical Research
2013-2016

West Bengal University of Animal and Fishery Sciences
2015

UW Health University Hospital
2014-2015

St. Joseph Regional Medical Center
2012

Idaho State University
2009-2010

Lady Hardinge Medical College
1987-1999

Emerging magnetic resonance imaging (MRI) biomarkers of hepatic steatosis have demonstrated tremendous promise for accurate quantification triglyceride concentration. These methods quantify the proton density fat‐fraction (PDFF), which reflects concentration triglycerides in tissue. Previous vivo studies compared MRI‐PDFF with histologic grading assessment steatosis. However, correlation underlying content remained unknown. The aim this ex study was to validate accuracy as an biomarker Using...

10.1002/hep.28012 article EN Hepatology 2015-07-30

Neural tissue engineering focuses on development of biomaterials that could support regeneration neurons after trauma as well injury caused by degenerative diseases. In this work we describe novel soft alginate hydrogels, which provide an adhesive matrix for rat and human facilitate neurite outgrowth. Only prepared with sub-stoichiometric concentrations Ca²⁺, Ba²⁺, Sr²⁺ cations cross-linking no >10% all potentially available gelation sites in alginate, facilitated rapid abundant outgrowth...

10.1089/ten.tea.2011.0097 article EN Tissue Engineering Part A 2011-07-20

Objective Using multidisciplinary treatment modalities the majority of children with cancer can be cured but we are increasingly faced therapy-related toxicities. We studied brain morphology and neurocognitive functions in adolescent young adult survivors childhood acute, low standard risk lymphoblastic leukemia (ALL), which was successfully treated chemotherapy. expected that intravenous intrathecal chemotherapy administered will affect grey matter structures, including hippocampus...

10.1371/journal.pone.0078599 article EN cc-by PLoS ONE 2013-11-12

Visceral leishmaniasis (VL) or Kala-azar has been a major public health problem in Bihar, India, for several decades. A few VL infected districts including Vaishali have reported >600 cases annually. Hence, 2015, the Government of India entrusted ICMR-Rajendra Memorial Research Institute Medical Sciences, Patna, to implement an integrated control strategy achieving elimination target (<1 case per 10,000 people at block level) District Bihar.This study was conducted between January 2015 and...

10.1371/journal.pntd.0008254 article EN cc-by PLoS neglected tropical diseases 2020-05-04

Existing organ weight charts used by pathologists for patients undergoing medical autopsy do not illustrate the effect of obesity and age on weights among a general population older individuals with multiple comorbidities.We retrospectively reviewed 300 reports to extract data analyze weights.In both men women, there were statistically significant increases in body mass index (BMI) but decreases liver, spleen, kidneys. In men, increased was associated left ventricular wall thickness, whereas...

10.1097/paf.0b013e3182518e5f article EN American Journal of Forensic Medicine & Pathology 2012-07-26

In the developing mammalian brain, inhibition of NMDA receptor can induce widespread neuroapoptosis, inhibit neurogenesis and cause impairment learning memory. Although some mechanistic insights into adverse neurological actions these antagonists exist, our understanding full spectrum developmental events affected by early exposure to chemical agents in brain is still limited. Here we attempt gain impact pharmacologically induced excitatory/inhibitory imbalance infancy on proteome using mass...

10.1371/journal.pone.0092831 article EN cc-by PLoS ONE 2014-04-07

Acute poisoning is one of the major medical emergencies with significant morbidity and mortality.Most due to intention deliberate self-harm. [1]Accidental occupational exposures pesticides leading acute or chronic have been seen in farmers children.The World Health Organization (WHO) reported that around 0.3 million people die various annually, out which 200000 deaths are organophosphorous alone. [2,3]The incidence much more higher developing resource-limited countries.Agricultural such as...

10.4103/ijccm.ijccm_207_18 article EN Indian Journal of Critical Care Medicine 2018-01-01

Abstract Background Breast cancer in females and prostate males are two of the most common cancers United States, literature suggests that they share similar features. However, it is unknown whether occurrence these at county level States correlated. We analyzed Caucasian age-adjusted average annual incidence rates for breast from National Cancer Institute State Registries to determine there was a spatial correlation between conditions had patterns. Results There significant by (r = 0.332, p...

10.1186/1476-072x-8-53 article EN cc-by International Journal of Health Geographics 2009-09-29

Visceral leishmaniasis (VL) in Bihar State (India) continues to be endemic, despite the existence of effective treatment and a vector control program disease morbidity. A clear understanding spatio-temporal distribution VL may improve surveillance implementation. This study explored trends dynamics endemicity at meso-scale level Vaishali District, based on geographical information systems (GIS) tools spatial statistical analysis. GIS database was used integrate case data from area between...

10.1186/s13071-018-2707-x article EN cc-by Parasites & Vectors 2018-04-02

Since May 2001, imatinib mesylate has become the first-line therapy for chronic myeloid leukemia (CML) but survival pattern by age, sex, and ethnicity is not clear.We analyzed Surveillance, Epidemiology, End Results (SEER*Stat) database to compare rates in CML among Caucasians, African-Americans (AA), other races, also within each race see differences from pre-imatinib (1973-2000) post-imatinib eras (2002-2008). We used Z-tests SEER*Stat relative categorized race, gender, age groups (all...

10.3109/0284186x.2012.707784 article EN Acta Oncologica 2012-11-26

Journal Article IGF-loaded silicon and zinc doped brushite cement: physico-mechanical characterization in vivo osteogenesis evaluation Get access Sahar Vahabzadeh, Vahabzadeh W. M. Keck Biomedical Materials Research Laboratory, Department of Chemistry, School Mechanical Engineering, Washington State University, Pullman, WA 99164-2920, USA. Fax: +1 (509) 335-4662; Tel: 335-7461 Search for other works by this author on: Oxford Academic Google Scholar Amit Bandyopadhyay, Bandyopadhyay Susmita...

10.1039/c5ib00114e article EN Integrative Biology 2015-11-04

There exists a north-south pattern to the distribution of prostate cancer in U.S., with north having higher rates than south. The current hypothesis for spatial this disease is low vitamin D levels individuals living at northerly latitudes; however, explanation only partially explains incidence cancer. Using U.S. county-level ecological study design, we provide evidence that other meteorological parameters further explain variation across In general, colder temperature and drier climate...

10.1186/1476-072x-9-19 article EN cc-by International Journal of Health Geographics 2010-01-01

Remote sensing and geographical information technologies were used to discriminate areas of high low risk for contracting kala-azar or visceral leishmaniasis. Satellite data digitally processed generate maps land cover spectral indices, such as the normalised difference vegetation index wetness index. To map estimated vector abundance indoor climate data, local polynomial interpolations based on weightage values. Attribute layers prepared illiteracy unemployed proportion population...

10.1590/s0074-02762012000500007 article EN cc-by Memórias do Instituto Oswaldo Cruz 2012-07-29

Epidemiological studies to assess risk factors for breast cancer often do not differentiate between different types of cancers. We applied a general linear model determine whether data from the Surveillance, Epidemiology, and End Results Program on annual county level age-adjusted incidence rates with without estrogen receptors (ER+ ER-) were associated environmental pollutants.Our final explained approximately 38% variation in rate ER+ cancer. In contrast, we only able explain 14% ER- same...

10.1186/1476-072x-10-32 article EN cc-by International Journal of Health Geographics 2011-01-01

Kala-azar or visceral leishmanisis (VL) is known to be endemic in several States of India including West Bengal (WB). Only meager information available on the vector dynamics its species, Phlebotomus argentipes particularly relation control measure from this State. Hence, a pilot study was undertaken assess strategy and impact two districts WB, India.

10.4103/0971-5916.164260 article EN The Indian Journal of Medical Research 2015-01-01

Abstract A subset of coronary arterial dissections is associated with eosinophilic periarteritis ( ECPA ); however, the pathogenesis process remains unclear. Mast cells normally reside in adventitia and are known mediators inflammatory conditions such as type I hypersensitivity reactions. We report two cases which dissection was detected at autopsy. Tryptase, CD 68, 4, 8, 1a immunohistochemical staining performed to better characterize inflammation. While eosinophils represented a prominent...

10.1111/1556-4029.12752 article EN Journal of Forensic Sciences 2015-03-16

Methadone continues to be a widely used maintenance therapy for opiate dependence. However, methadone-related deaths have been reported frequently over 4 decades now. Anoxic brain injury with pulmonary edema secondary respiratory depression is the recognized mechanism of methadone death, although pathological intracranial findings are rarely described in deaths. A selective area has never use. We present case 23-year-old man who had acute necrosis bilateral globi pallidi and systemic...

10.1097/paf.0b013e31823a8b1e article EN American Journal of Forensic Medicine & Pathology 2013-01-29

Remote sensing was applied for the collection of spatio-temporal data to increase our understanding potential distribution kala-azar vector Phlebotomus argentipes in endemic areas Vaishali district Bihar, India. We produced monthly maps normalized difference vegetation index (NDVI) based on from thematic mapper (TM) sensor onboard Landsat-5 satellite. Minimum, maximum and mean NDVI values were computed each month compared with concurrent incidence density. Maximum (R2 = 0.55 R2 0.60,...

10.4081/gh.2012.104 article EN cc-by-nc Geospatial health 2012-11-01

Visceral leishmaniasis, or kala-azar, is recognised as a serious emerging public health problem in India. In this study, environmental parameters, such land surface temperature (LST) and renormalised difference vegetation indices (RDVI), were used to delineate the association between variables Phlebotomus argentipes abundance representative endemic region of Bihar, The adult P. collected September 2009-February 2010 using hand-held aspirator technique. distribution was analysed with LST RDVI...

10.1590/0074-0276108022013012 article EN cc-by Memórias do Instituto Oswaldo Cruz 2013-04-01

Indoor residual spraying (IRS) is the mainstay for vector control intervention of visceral leishmaniasis (VL) in India. Little known on effects IRS different household types. Here, we assessed if with insecticides has an equal and interventional effect all types a village. We also developed combined spatial-risk map sand fly, Phlebotomus argentipes density analytical model based characteristics, insecticide susceptibility IRS-status to explore spatio-temporal distributions at micro-scale...

10.1186/s13071-019-3670-x article EN cc-by Parasites & Vectors 2019-08-22

10.1016/j.jtcvs.2016.07.056 article EN publisher-specific-oa Journal of Thoracic and Cardiovascular Surgery 2016-08-06

To evaluate the relative survival rates for patients with metastatic bladder cancer (MBC) over last two decades in United States: 1991-2000 and 2001-2010.We used Surveillance, Epidemiology, End Results (SEER*Stat) Program to analyze 6-month 12-month of American Joint Committee on Cancer (AJCC) Stage IV included SEER database. We Z-test SEER*Stat compare among cohorts categorized by race, gender, age groups (<60 ≥ 60 years).The dataset comprised 4195 7629 AJCC periods 2001-2010, respectively....

10.4103/0973-1482.140982 article EN Journal of Cancer Research and Therapeutics 2015-01-01
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