A5063366847- Cystic Fibrosis Research Advances
- Family and Disability Support Research
- Child Nutrition and Feeding Issues
- Adolescent and Pediatric Healthcare
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- Pediatric health and respiratory diseases
- Neurogenetic and Muscular Disorders Research
- Childhood Cancer Survivors' Quality of Life
- Congenital Ear and Nasal Anomalies
- Respiratory viral infections research
- Neuroscience of respiration and sleep
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Obstructive Sleep Apnea Research
- Infections and bacterial resistance
- Autism Spectrum Disorder Research
- Sleep and Wakefulness Research
- Venous Thromboembolism Diagnosis and Management
- Foreign Body Medical Cases
- Genetic Neurodegenerative Diseases
- Nematode management and characterization studies
- Scoliosis diagnosis and treatment
- Blood Coagulation and Thrombosis Mechanisms
Marmara University
2021-2025
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2024-2025
ABSTRACT Background CF R.I.S.E is a program that helps people with Cystic Fibrosis (pwCF) transition from pediatric to adult care. In 2022, we adapted it S.O.B.E in Turkish during training session. This project aims present the results of program. Methods study included 81 pwCF aged 16–25, divided into two groups: standard S.O.B.E. group ( n = 39) and modified 42). The received face‐to‐face education. Both groups participated online sessions written materials. knowledge levels were evaluated...
OBJECTIVE:The aims of this multi-center study were to describe the characteristics children receiving long-term home mechanical ventilation (HMV) in İstanbul and compare patients non-invasive invasive ventilation. MATERIAL AND METHODS:This cross-sectional multicenter included all HMV followed by admission six tertiary hospitals.The data collected between May 2020 2021.Demographic regarding from patient charts. RESULTS:The 416 participants.The most common diagnoses neuromuscular (35.1%)...
Although cystic fibrosis (CF) mainly affects the respiratory and gastrointestinal systems, it may frequently present with musculoskeletal manifestations including bone fractures, low mineral density, spinal pathologies. Assessment of pathologies in CF patients is vital importance because effects on lung capacity posture are clearly defined. The frequency vertebral has yet to be determined. aim this study was investigate scoliosis hyperkyphosis relationship coronal, sagittal, spinopelvic...
Although modulator therapies have proven effective in cystic fibrosis (CF) access is limited due to reimbursement issues Turkey. We aimed examine anxiety and depression levels of people with CF (pwCF) their caregivers according treatment. Participants genetically eligible for elexacaftor/tezacaftor/ivacaftor (ETI) were divided into Group 1 (access via court decision, not yet on treatment) 2 (unable issues). Genetically ineligible participants formed 3. All pwCF parents those under 18...
Objective: Sleep-disordered breathing (SDB) is a prevalent concern in individuals with neuromuscular diseases (NMD), significantly impacting respiratory function and sleep quality. This study aimed to retrospectively evaluate the demographic, clinical, baseline polysomnographic data of children NMD investigate guiding effect Pediatric Sleep Questionnaire (PSQ) modified Epworth Sleepiness Scale (ESS-CHAD) detecting SDB. Method: A retrospective analysis was conducted on aged 2-18 years who...
Background We hypothesize that Lung Clearance Index (LCI) would be superior to spirometry in diagnosing early-stage respiratory diseases earlier and, more precisely, patients who received medical or surgical treatment for empyema. Methods Children over five diagnosed with empyema at least six months ago were recruited. In addition, a control group was created from healthy individuals between the ages of 5 18 years. Spirometry and LCI performed both groups. Results The spirometric values...
Abstract Background Cystic fibrosis (CF) patients have a limited life expectancy, but significant medical advances now highlight the need for successful transition programs from pediatric to adult care. The goal of this project was introduce program CF R.I.S.E (Responsibility. Independence. Self‐care. Education.) center with resources at Marmara University (MU). Methods adapted and translated into Turkish Foundation's permission. A team experts collaborated develop educational materials...
The aim of this study was to evaluate the prevalence anxiety, depression, sleep, and associated factors in caregivers children with spinal muscular atrophy (SMA).Beck Depression Inventory (BDI), State-Trait Anxiety Inventory-State (STAI-S), Inventory-Trait (STAI-T), Pittsburgh Sleep Quality Index (PSQI) were used assess sleep quality SMA. Higher scores indicated worse outcome for all three questionnaires.Fifty-six SMA included study. Median age 6 (3.2-10) years mean 37.0 ± 6.5 years. BDI,...
Abstract Background Cystic fibrosis (CF) is an autosomal recessive disease caused by variants of CFTR gene. Over 2000 have been identified, and new drugs called modulators developed to target specific defects in the protein. However, these are only suitable for patients with certain , eligibility rates vary depending on race geographical region. This study aimed reveal detailed genotype clinical characteristics people CF (pwCF) at our center Turkey, a developing country, who not eligible...
Background : Primary ciliary dyskinesia (PCD) is associated with ventilation defects and heterogeneous impairment of pulmonary function. Spirometry may underestimate PCD severity complexity. This study aimed to evaluate spirometry, lung clearance index (LCI), impulse oscillometry (IOS) in children healthy controls, compare them terms early detection disease. Methods In this cross-sectional, prospective study, participants included aged 6-18 years age-matched controls. Lung function tests...
Central sleep apnea (CSA) is a rare condition in children; however, it can cause significant morbidity if not diagnosed early. We aimed to increase the knowledge about CSA children by describing clinical characteristics of with at our center.
Abstract Backgrounds Genetic variants in CF transmembrane conductance regulator ( CFTR ) gene causes cystic fibrosis (CF), a prevalent autosomal recessive disorder. More than 2000 have been described as disease causative. This study aims to delineate the genotypic and phenotypic landscape of among people with (pwCF) followed at largest center Turkey. Methods We conducted descriptive retrospective analysis 481 patients registered European Society Patient Registry Marmara University Selim...
Background: Previously, Cystic Fibrosis (CF) patients faced a limited life expectancy, but significant medical advances now highlight the need for successful transition programs from pediatric to adult care. Methods: The aim of this project was implement CF R.I.S.E. program, structured in center with resources at Marmara University. program adapted and translated into Turkish permission Foundation. A multidisciplinary team collaborated translation adaptation process educational materials...
Abstract Background and Objectives Children with tracheostomies are at increased risk of tracheostomy‐related complications require extra care. Standardized training programs for caregivers can improve tracheostomy care reduce complications. In this study, we compared caregiver knowledge skill scores after a standardized theoretical practical program on (IStanbul PAediatric Tracheostomy (ISPAT) project) immediately 1 year post‐training evaluated how affected the children's clinical outcomes....
BACKGROUND AND AIM: Pulmonary embolism (PE) is a potentially life-threatening disease in children. The objective of the study to evaluate utility adult-based pulmonary rule-out criteria (PERC), Pediatric PE Model, and D-dimer diagnosis children.The consisted patients under 18 years age who were consulted Pulmonology Clinic for evaluation PE. Patients divided into two groups based on confirmation group with presence (n = 20) children diagnosed absence 28) clinically suspected but negative...
<b>Background:</b> Prolonged survival of patients with chronic respiratory failure increased the number receiving long-term home ventilation (LTHV). This study aimed to describe aetiology and patterns use LTHV in Istanbul. <b>Methods:</b> cross-sectional included children on invasive (IV) non-invasive (NIV) from six tertiary hospitals. Data including underlying diagnosis were collected patients9 charts. <b>Results:</b> Study 416 patients. The most common diagnoses neuromuscular (35.1%)...
Introduction-Aim: Duchenne muscular dystrophy (DMD) is the most common myotonic characterized by progressive muscle dysfunction. Respiratory muscles are also impacted in DMD. In this study, we planned to analyze demographic and respiratory characteristics, polysomnography (PSG), capnography evaluations of patients with DMD who applied our Pediatric Pulmonology outpatient clinic last year. Material-Method: Thirty-nine between January August 2022 were included. Demographic characteristics...