A5001687913- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- Tracheal and airway disorders
- Pediatric health and respiratory diseases
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Obstructive Sleep Apnea Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Child Nutrition and Feeding Issues
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Family and Patient Care in Intensive Care Units
- Medical Imaging and Pathology Studies
- Simulation-Based Education in Healthcare
- Transplantation: Methods and Outcomes
- Bone Metabolism and Diseases
- Tumors and Oncological Cases
- Restraint-Related Deaths
- Sarcoidosis and Beryllium Toxicity Research
- Dysphagia Assessment and Management
- Congenital Ear and Nasal Anomalies
- Pneumothorax, Barotrauma, Emphysema
- Vasculitis and related conditions
Istanbul University
2023-2025
University of Health Sciences Antigua
2025
Sağlık Bilimleri Üniversitesi
2021-2025
Yedikule Teaching Hospital
2019-2022
Marmara University
2014-2021
Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi
2021
Istanbul Medeniyet University
2021
Chest Diseases Hospital
2021
Türkisch-Deutsche Universität
2021
OBJECTIVE:The aims of this multi-center study were to describe the characteristics children receiving long-term home mechanical ventilation (HMV) in İstanbul and compare patients non-invasive invasive ventilation. MATERIAL AND METHODS:This cross-sectional multicenter included all HMV followed by admission six tertiary hospitals.The data collected between May 2020 2021.Demographic regarding from patient charts. RESULTS:The 416 participants.The most common diagnoses neuromuscular (35.1%)...
Introduction: Advances in neonatal and pediatric intensive care have improved patient survival rates, emphasizing the need for respiratory support cases of chronic failure, resulting establishment Turkish National Pediatric Patients Receiving Home Mechanical Ventilation (HMV) Support Registration System 2023. This study aims to present initial findings registry. Methods: In this cross-sectional study, epidemiological demographic data was obtained from registry compared between invasive...
Abstract Background The prevalence of non-cystic fibrosis (CF) bronchiectasis is increasing in both developed and developing countries recent years. Although the main features remain similar, etiologies seem to change. Our aim was evaluate clinical laboratory characteristics our non-CF patients compare these with historical cohort 2001. Methods One hundred four children followed between 2002 2019 were enrolled. Age diagnosis, underlying etiology microorganisms sputum culture recorded....
Abstract Introduction and Aim Obstructive sleep apnea syndrome (OSAS) is frequent in children with Down (DS) polysomnography (PSG) recommended for all DS. However PSG not always available alternative diagnostic methods are needed. The aim of the study was to evaluate feasibility validity home polygraphy (HPG) Methods A national DS association contacted aged 6 18 years who accepted participate were recruited. Otorhinolaryngologic evaluation, in‐lab HPG performed. OSAS diagnosed by an...
Abstract Background Cystic fibrosis (CF) genotyping has garnered increased attention since the discovery of cystic transmembrane conductance regulator (CFTR) gene in 1989 led to identification over 1700 mutations on chromosome 7. Yet, little is known about genetic profile CF patients Turkey. This study sought determine mutation distribution among seeking care at Marmara University. Methods Two hundred fifty previously diagnosed were included study. CFTR exons 1 27 amplified by a polymerase...
Due to advances in technology, home ventilation children has increased recent years. The provision of proper care for a home-ventilated (HV) child can have strong impact on the lifestyle caregivers. aim this study was evaluate depression and anxiety levels mothers HV during current COVID-19 pandemic compare them those healthy peers.This cross-sectional conducted (n = 21) control group peers 32) by means questionnaire completed both groups. Psychometric scales, such as Beck Depression...
Tracheostomy-related morbidity and mortality mainly occur due to decannulation, misplacement, or obstruction of the tube. A standardized training can improve skills confidence caregivers in tracheostomy care (TC).Our primary aim was evaluate efficiency program on knowledge (changing-suctioning tube) participants regarding TC.Sixty-five children with were included. First, evaluated written test about TC participated practical tests. Then, they asked participate a session, including...
Although voriconazole, a triazole antifungal, is safe drug, treatment with this agent associated certain adverse events such as hepatic, neurologic, and visual disturbances. The current report presents two cases, one 9-year-old boy the other 17-year-old girl, who experienced neurologic side effects voriconazole therapy. Our aim to remind readers of therapy in order prevent unnecessary investigations especially for psychological ophthalmologic problems. first case was cystic fibrosis invasive...
Chest physiotherapy (CP) is a recommended treatment modality in primary ciliary dyskinesia (PCD).Primary aim was to compare the efficacy and safety of conventional chest (CCP) oscillatory positive expiratory pressure therapy (OPEPT). Secondary aims were exacerbation rate, time until first exacerbation, patient compliance comfort between two CP methods.This 6 month randomized, controlled crossover trial. Patients >6 years age with PCD randomized into groups, group assigned OPEPT (Acapella®)...
Sleep disordered breathing is a common problem in childhood that encompasses spectrum of disorders extending from primary snoring to obstructive sleep apnea. This study aims investigate the results children undergoing evaluation with polysomnography laboratory tertiary care hospital.Demographic and clinical features as well associated symptoms, scores pediatric questionnaire Pittsburgh quality index are retrospectively evaluated.Totally 131 patients were evaluated, which 47.3% (n=62) females...
Children with Down syndrome (DS) are at increased risk for obstructive sleep apnea (OSA) compared children without DS, reported prevalence of 31 ± 75% among clinical-based samples. We aimed to find out whether there is any effect OSA on periodontal and dental health in DS.Overnight polysomnography (PSG) was performed. defined as Apnea-Hypopnea Index (AHI) ≥ 1/h. received a full mouth examination that included probing depths (PD), plaque index (PI), gingival (GI), bleeding (BOP) six sites per...
Tracheostomy care in children may be challenging, due to lack of knowledge healthcare providers (HCPs). The aim this study was determine the level HCP who follow patients with tracheostomy and increase theoretical training a simulation laboratory.ISPAT (IStanbul PAediatric Tracheostomy), multidisciplinary team for established program prepared. Participants were subjected practical pretests which evaluated their levels skills care, follow-up, treatment patient tracheostomy. After given...
Background: The objective of the study was to assess diagnostic efficacy coulometric endpoint method and compare it with classic Gibson&Cooke chloridometer methods. Methods: This is a prospective clinical comparing two conventional sweat testing methods in previously diagnosed cystic fibrosis (CF) patients non-CF control group. All individuals underwent simultaneous collections. One sample sweat, collected by CFΔ collector coil system, analyzed methods: titrimetric Cl- measurement (Sherwood®...
Primary ciliary dyskinesia (PCD) is a genetic disease characterized by impaired mucociliary function. Immunofluorescence (IF) staining of proteins gaining importance in the diagnosis PCD recent years. In this study results IF 36 Turkish patients with suspected were reported. <b>Methods:</b> Thirty six included study. Nasal brush samples evaluated antibodies against DNAH5, GAS8, DNAH11, RSPH9 proteins. some cases, further analyses performed tackling DNALI1 and CCDC39. <b>Results:</b> Mean age...
Abstract Introduction Bronchiolitis obliterans (BO) is mainly caused by infections and hematopoietic stem cell transplantation (HSCT). This study aimed to investigate the health‐related quality of life (HRQOL) children with BO compared healthy also assess HRQOL according etiology. Methods Postinfectious (group 1) post‐HSCT 2) patients were included in study. was assessed Short Form‐36 (SF‐36) St George's Respiratory Questionnaire (SGRQ). Correlations between demographic clinical...
Introduction The number of children requiring long-term invasive home ventilation (LTIHV) has increased worldwide in recent decades. training physicians caring for these is crucial since they are at high risk complications and adverse events. This study aimed to assess the efficacy a comprehensive high-fidelity simulation-based program on LTIHV. Methods A multimodal tracheostomy ventilator management was prepared by ISPAT (IStanbul PAediatric Tracheostomy) team. Participants were subjected...
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a rare disorder recently included in idiopathic interstitial pneumonias according to the updated American Thoracic Society/European Respiratory Society classification. IPPFE characterized by pleural and subpleural parenchymal fibrosis causing volume loss predominantly upper lung lobes. Age of onset variable, mainly occurs third fourth decades. We present 16 year old patient with 2-year history exertional dyspnea, nonproductive cough...
Objectives: The study aimed to evaluate the surgical results of antireflux surgery (ARS) in neurologically impaired children with gastroesophageal reflux disease (GERD) who underwent our clinic. Patients and methods: This retrospective included 84 (50 males 34 females; mean age: 44.4±49 months; range, 2 224 months) between January 2011 October 2016. Data on patient demographics, indications for surgery, preoperative symptoms, diagnostic tests, procedures, complications, reoperations were...
Behçet's disease (BD) is a rare autoimmune and chronic inflammatory vasculitis, characterized by relapsing episodes of oral aphthous genital ulcers, skin lesions, ocular lesions vascular involvement. Pulmonary artery involvement in BD but it carries high mortality risk. In this article, we report 15-year-old male patient presented with two-month history hemoptysis, cough, fewer weight loss. On physical examination, auscultation revealed decreased breath sounds at left lung base. Bronchoscopy...