A5072468128- Cystic Fibrosis Research Advances
- Neonatal Respiratory Health Research
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Diagnosis and Treatment
- Pediatric health and respiratory diseases
- Bacterial biofilms and quorum sensing
- Family and Patient Care in Intensive Care Units
- Infant Development and Preterm Care
- Airway Management and Intubation Techniques
- Infant Nutrition and Health
Mersin Üniversitesi
2025
Ege University
2022-2024
Abstract Introduction Cystic fibrosis transmembrane conductance regulator (CFTR) modulator drugs target the underlying defect and improve CFTR function. They are a part of standard care in many countries, but not all patients eligible for these due to age genotype. Here, we aimed determine characteristics non‐eligible modulators CF registry Turkey (CFRT) highlight their clinical needs. Methods This retrospective cohort study included patient data from CFRT 2021. The decision eligibility was...
Dynamic hyperinflation (DH) is a major contributor to exercise intolerance in patients with obstructive lung diseases. However, it has not been investigated children bronchiectasis (BE). We aimed investigate dynamic ventilatory responses and their influence on functional capacity BE.Forty BE (mean forced expiratory volume 1 s [FEV1 ] = 78 ± 19%pred) were included. Six-minute walk test (6MWT) was conducted using Spiropalm 6MWT® for evaluating including inspiratory (IC), minute ventilation...
Experience of flexible bronchoscopy in the pediatric pulmonary diseases clinicIntroduction: Flexible is a valuable method diagnosis and treatment respiratory tract children.This study aimed to examine indications for results children. Materials Methods:The included patients aged 0-18 years who underwent between 1 January 2017 31 December 2022.The were evaluated demographic characteristics, bronchoscopy, comorbidities, findings, bronchoalveolar lavage. Results:During defined period, total 410...
Aim: Cystic fibrosis (CF) is an autosomal recessive disorder.Although it considered as epithelial disease due to impaired chloride transport, its pathogenesis remains unclear.CF classified a syndrome with congenital defects of phagocyte in recent human inborn errors immunity phenotypic classifications.Neutrophils are the most effective cells eradication bacterial infections such Pseudomonas aeruginosa.The aim present study was investigate functions pseudomonas colonized CF patients.Materials...
Since January 2015, the Cystic Fibrosis National Newborn Bloodspot Screening (CF-NBS) program has been implemented in Turkey with two samples of immune reactive trypsinogen (IRT-1/IRT-2) testing.
Abstract Objective Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared a global pandemic in March 2020, with millions of infected cases worldwide. Although the course is usually mild pediatric age group, there are unknown factors patients chronic lung diseases. The aim this study to determine demographic characteristics and clinical cystic fibrosis who contracted COVID-19 infection. Methods A total 128 were under follow-up...
screening program (2) .Mutation of the CF transmembrane conductance regulator (CFTR) protein, which is a complex chloride channel protein that exists in all exocrine tissues, causes CF.Irregular transportation ions like sodium, and bicarbonate (HCO 3 ) results thick viscous secretions lungs, pancreas, liver, intestines genital system increases amount salt sweat glands (3,4) .Chronic cough, phlegm ABSTRACT Objective: Pseudo-Bartter syndrome (PBS) complication cystic fibrosis (CF) accompanied...
Introduction: Cystic fibrosis (CF) is an autosomal recessive disorder. Although it considered as epithelial disease due to impaired chloride transport, its pathogenesis not clear. CF classified a syndrome with congenital defects of phagocyte in recent human inborn errors immunity phenotypic classification. Neutrophils are the most effective cells eradication bacterial infections such Pseudomonas aeruginosa . The aim this study was investigate functions pseudomonas colonized cystic patients....