A5000746595- Pediatric health and respiratory diseases
- Asthma and respiratory diseases
- Gut microbiota and health
- Parasite Biology and Host Interactions
- Physiological and biochemical adaptations
- Probiotics and Fermented Foods
- Dermatology and Skin Diseases
- Neurobiology and Insect Physiology Research
- Amphibian and Reptile Biology
- Immune Cell Function and Interaction
- Children's Physical and Motor Development
- Physical Education and Gymnastics
- Renal Transplantation Outcomes and Treatments
- Crustacean biology and ecology
- Environmental Toxicology and Ecotoxicology
- Linguistics and Language Studies
- Muscle metabolism and nutrition
- Infectious Aortic and Vascular Conditions
- Migration, Racism, and Human Rights
- Venomous Animal Envenomation and Studies
- Photoreceptor and optogenetics research
- Neuroscience of respiration and sleep
- Medical and Biological Ozone Research
- Environmental Chemistry and Analysis
- Marine Invertebrate Physiology and Ecology
Universidade Federal de São Paulo
2017-2023
Hospital de Clínicas da Unicamp
2022
Universidade Estadual de Campinas (UNICAMP)
2022
Deakin University
2022
Universidade de São Paulo
1963-2015
Universidad Católica Nuestra Señora de la Asunción
2008
Introduction Asthma, an inflammatory lung disease, disproportionately affects women in adulthood and is associated with a decline estrogen levels during the menstrual cycle menopause. To study asthma symptoms menopause, we used mouse model of postmenopausal via ovariectomy (OVx). Similar to human previously discovered that re-exposure allergic OVx mice allergen exacerbates inflammation. Surprisingly, found probiotic treatment alleviates this exacerbation produces acetate as one its...
Asthma is a chronic inflammatory disease that affects more females than males after puberty, and its symptoms severity in women change during menstruation menopause. Recently, evidence has demonstrated interactions among the microbiota, female sex hormones, immunity are associated with development of autoimmune diseases. However, no studies have investigated if therapeutic gut microbiota modulation strategies could affect asthma exacerbation Here we aimed to examine preventive effects...
A dialyzable, acetylcholine-like material exists in homogenates of globiferous pedicellariae the sea urchin Lytechinus variegatus. Its pharmacological characterization was obtained on basis responses guinea pig ileum, rat uterus, blood pressure dog, amphibian heart, longitudinal muscle holothurian, and protractor lantern. Some data were statistically treated, an attempt made to determine a ratio potency between acetylcholine.
Abstract The phenotypes of allergic airway diseases are influenced by the interplay between host genetics and gut microbiota, which may be modulated probiotics. We investigated probiotic effects on inflammation in A/J C57BL/6 mice. mice had increased microbiota diversity compared to at baseline . Acetate producer probiotics differentially altered genus abundance specific bacteria, such as Akkermansia Allistipes , mouse strains. induced followed treatment found that only exhibited decreased...
Allergic asthma is a chronic disease mainly characterised by eosinophil inflammation and airway remodelling. Many studies have shown that the gut microbiota of allergic individuals differs from non-allergic individuals. Although high levels bifidobacteria been associated with healthy persons, Bifidobacterium adolescentis ATCC 15703, bacteria, has in some clinical studies. The relationship between B. 15703 or allergies not well elucidated, its effect may be dependent on host’s genetic profile...
Allergic contact dermatitis (ACD) is a common allergic skin disease that affects individuals subjected to different antigen exposure conditions and significantly impacts the quality of life those affected. Numerous studies have demonstrated probiotics suppress inflammation through immunomodulatory effects. In this study, we aimed evaluate effect probiotic Bifidobacterium longum 5 1A as preventive treatment for ACD using an oxazolone-induced murine model. We B. exerted prophylactic on...
Allergic contact dermatitis (ACD) is an inflammatory skin reaction whose incidence has increased and been associated with a dietary pattern rich in saturated fats refined sugars. Considering the of ACD lack research about influence short-term high-sugar diet on dermatitis, our aim to improve understanding ACD. We introduced sugar fifteen days before inducing oxazolone, mice, maintained it until end experiment, which lasted three weeks total. The model cholesterol triglycerides liver,...
Asthma is an inflammatory lung disease that affects more women than men in adulthood. Clinical evidence shows hormonal fluctuation during the menstrual cycle and menopause are related to increased asthma severity women. Considering life expectancy has most now undergo menopause, strategies prevent worsening of symptoms particularly important. A recent study from our group showed re-exposure ovariectomised allergic mice antigen (ovalbumin) leads exacerbation inflammation similar clinical...
Este trabalho foi desenvolvido no âmbito do projeto “Instalação eficiente de povoamentos eucalipto” com o objetivo estudar alternativas mobilização solo ajustadas à escala da propriedade (minifúndio dominante Centro/Norte país), associadas a menor intervenção e impacto ambiental. Foram consideradas para comparação algumas técnicas utilizadas em propriedades maior dimensão. Instalaram-se 4 ensaios na região Centro (três Cantanhede um Mortágua; cada 65 270 plantas, considerando 3 repetições)....
O consumo de oxigênio Limnodrilus hoffmeisteri foi medido a 25°C, em água equilíbrio com atmosferas contendo 21, 15, 10, 5, 2.5 e 1% oxigênio, (no escuro) sem adição monóxido carbono quantidade suficiente para saturar hemoglobina do sangue. normal médio Limnodrilus, é 1,02 mm3/mg (seco)/hora.
P242 Current issues in drug monitoring point to a phenomenon known as time-dependent concentration, which is the increase blood levels through time despite fixed doses of drugs. Data regarding MMF show that there progressive mycophenolic acid (MPA) concentration first 3 weeks post-tx but therapeutic are reached by third month. The MoDIFY study (Modification Doses Improve Function Years) prospective, randomized compares low trough (C0) tacrolimus (TAC) + 2g/d (Group 1) regular C0 TAC 1500...
The present study deals with a species of enteropneust, Glossobalanus crozieri, focusing on two aspects its respiration: a) oxygen consumption and body mass, b) the influence environmental tension respiratory rate. Preliminarily, water content was shown to be 85% whole weight. regression coefficient wet mass (0.578) seems agree view that in enteropneusts respiration is mainly cutaneous. rate significantly reduced at O2 tensions from 76 mmHg downwards, suggesting conformity rather than regulation
P244 Therapeutic drug monitoring (TDM) is essential for transplant success. The use of multiple drugs requires a homogenous approach TDM in clinical practice. CyA best monitored by the blood level at second hour (C2). However, this has not been documented tacrolimus (TAC) and mycophenolic acid (MPA). We prospectively performed 12-hour pharmacokinetic (PK) studies days 7, 14, 30, 60 180 after kidney Tx, 37 pts with mean age 38±12y under TAC/MMF/Pred. TAC (n=155) MPA (n=145) PKs were available...