A5101811322- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Head and Neck Cancer Studies
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Renin-Angiotensin System Studies
- Brain Metastases and Treatment
- Cancer-related gene regulation
- Pancreatic and Hepatic Oncology Research
- Genetic factors in colorectal cancer
- Plant Disease Resistance and Genetics
- Lung Cancer Treatments and Mutations
- Bone health and treatments
- Meningioma and schwannoma management
- Glycosylation and Glycoproteins Research
- Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Viral-associated cancers and disorders
- Soft tissue tumors and treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Pancreatitis Pathology and Treatment
State Key Laboratory of Oncology in South China
2010-2017
Sun Yat-sen University Cancer Center
2011-2017
Sun Yat-sen University
2011-2017
Handan College
2017
Key Laboratory of Guangdong Province
2010-2014
Zero to Three
2011
Background: Elevated neutrophil to lymphocyte ratio (NLR) is linked with worse survival in many malignancies, whereas its association pancreatic cancer (PC) remains unclear.Methods: We retrospectively reviewed 95 patients locally advanced or metastatic PC receiving gemcitabine-based chemotherapy. The prognostic value of NLR was evaluated.Results: pretreatment (>5) observed 16 out 89 eligible patients, which identified as an independent factor for overall (OS). median OS elevated and normal...
BACKGROUND: Plasma Epstein-Barr virus (EBV) DNA is widely used in screening, monitoring, and prediction of relapse nonmetastatic nasopharyngeal carcinoma (NPC). However, data regarding utility plasma EBV metastatic NPC are rare. The current study was to test the prognostic implication level metastatic/recurrent patients treated with palliative chemotherapy. METHODS: measured at baseline thereafter start each treatment cycle 127 histologically proven Correlations pre-treatment post-treatment...
Elevated neutrophil to lymphocyte ratio (NLR) has been reported be associated with worse survival in many malignancies, whereas its role nasopharyngeal carcinoma (NPC) remains unclear. We retrospectively reviewed 363 consecutively, newly diagnosed, non-disseminated, and biopsy-proven NPC patients. Disease-specific (DSS), distant metastasis-free (DMFS), locoregional recurrence-free (LRFS) rates were compared according NLR level. Multivariate analysis was performed assess the prognostic value...
The C-reactive protein/albumin (CRP/Alb) ratio has been recently identified as a prognostic factor in various cancers, whereas its role remains unclear metastatic nasopharyngeal carcinoma (NPC). current study retrospectively analyzed 148 patients with NPC who underwent cisplatin-based chemotherapy and further evaluated the value of CRP/Alb association clinical characteristics these patients. optimal cut-off was 0.189 for ratio. high significantly associated elevated NLR,...
The aim of this study was to characterize the patterns recurrence in patients achieving pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer.Patients with cancer treated CRT and who achieved pCR from January 2004 December 2012 were collected. primary outcome measurement recurrence.Among 195 pCR, 18 developed recurrence. Furthermore, local occurred 1.5% (3/195), while distant metastases 7.7% (15/195), which included 7 lung metastases,...
Background and Objectives Systemic failure remains a predominant issue in locally advanced rectal cancer (LARC). A new strategy using capecitabine oxaliplatin (XELOX regimen) administered prior to then concomitant radiotherapy for high risk LARC is developed our practice. The aim of the present study was evaluate short‐term efficacy toxicities this strategy. Methods Patients were treated with one cycle XELOX regimen (oxaliplatin 130 mg/m 2 on day 1 1,000 twice daily 14 days every 3 weeks),...
Oxaliplatin (OXA)-induced carcinoembryonic antigen (CEA) surge was reported to be associated with a clinical benefit. The aim of this study investigate the phenomenon CEA in irinotecan-based chemotherapy.We retrospectively reviewed 132 patients metastatic colorectal cancer treated chemotherapy. Incidence and chemotherapy efficacy were investigated.Eleven 99 eligible (11.1%) had surges. None 11 showed progressive disease (four partial response, seven stable disease).A can induced by An early...
The routine application of neoadjuvant chemoradiotherapy for T3N0 rectal cancer remains controversial. aim this study was to use clinical, Magnetic resonance imaging, and pathological parameters identify a subgroup patients with low risk local recurrence who might be precluded from chemoradiotherapy.We retrospectively reviewed prospectively maintained database consecutive underwent curative resection. 166 pathologic confirmed tumor located 5-12 cm above the anal verge preoperative...
Schwannomas are nerve sheath tumors arising from Schwann cells. These usually present as benign, relatively slow-growing, solitary, encapsulated, painless masses. rarely occur in the vagina, and have not been fully recognized gynecological tumors. We herein describe case of a patient who presented with schwannoma occurring wall non-specific symptoms lasting for ~1 year. The vaginal mass was incidentally detected during sonographic examination referred surgical resection. surgery...
Head and neck squamous cell carcinoma (HNSCC) is a common cancer worldwide has poor prognosis. A biomarker predicting the clinical outcome of HNSCC patients could be useful in guiding treatment planning. Overexpression T lymphoma invasion metastasis 1 (Tiam1) protein been implicated migration neoplasms. However, its role progression needs to further validated. We detected expression Tiam1 normal tumor tissues determined association with outcomes HNSCC.We measured cancerous tissue samples...
Little was known with regard to the value of preoperative systemic restaging for patients locally advanced rectal cancer (LARC) treated neoadjuvant chemoradiotherapy (CRT). This study designed evaluate role chest and abdominal computed tomography (CT) scan or magnetic resonance imaging (MRI) on in LARC after CRT assess impact treatment strategy.Between January 2007 April 2013, 386 newly diagnosed consecutive who underwent received CT/MRI were included. Imaging results before analyzed.Twelve...
// Jing-Hua Tang 1, 2, * , Xin An 3, Xi Lin 4, Yuan-Hong Gao 5 Guo-Chen Liu 2 Ling-Heng Kong Zhi-Zhong Pan Pei-Rong Ding 1 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China Departments Colorectal Surgery, Sun Yat-sen University Center, 3 Medical Oncology, 4 Ultrasound, Radiation These authors have contributed equally to this work Correspondence to: Ding, e-mail: dingpr@mail.sysu.edu.cn Pan, panzhzh@sysucc.org.cn Keywords:...
Abstract Background and Objectives This analysis aims to evaluate the value of early surveillance within 6 months after resection for stage II/III colorectal cancer (CRC). Methods Patients with CRC who received surgery curative intent were included. CT scans chest, abdomen, pelvis performed evaluated. Results Among 150 patients included in study, 10 (1 occurred II disease 9 III) diagnosed as recurrence surgery. The proportion was significantly higher III than ( P = 0.01). likelihood...