A5078697891- Gut microbiota and health
- Antioxidant Activity and Oxidative Stress
- Genomics, phytochemicals, and oxidative stress
- Antimicrobial Peptides and Activities
- Probiotics and Fermented Foods
- Shape Memory Alloy Transformations
- Phytochemicals and Antioxidant Activities
- Animal Nutrition and Physiology
- Glutathione Transferases and Polymorphisms
- Immune Response and Inflammation
- Corrosion Behavior and Inhibition
- Moringa oleifera research and applications
- Ruminant Nutrition and Digestive Physiology
- Vascular Procedures and Complications
- Selenium in Biological Systems
- NF-κB Signaling Pathways
- Seaweed-derived Bioactive Compounds
- Insect Utilization and Effects
- High-Temperature Coating Behaviors
- Kruppel-like factors research
- Natural Language Processing Techniques
- Medicinal Plants and Neuroprotection
- Essential Oils and Antimicrobial Activity
- Redox biology and oxidative stress
- Biofuel production and bioconversion
Hainan University
2019-2025
West China Medical Center of Sichuan University
2024
Feed Research Institute
2024
Chinese Academy of Agricultural Sciences
2024
Ministry of Agriculture and Rural Affairs
2024
University of Science and Technology Beijing
2023
Center for Devices and Radiological Health
2019-2022
United States Food and Drug Administration
2020-2022
Office of Science
2019-2022
Inner Mongolia Agricultural University
2016-2019
Lipopolysaccharide (LPS) was selected as a stimulus to investigate its effect on cell viability and oxidative stress in bovine mammary epithelial cells (BMEC) by detecting the relative growth rate (RGR), antioxidant indicators inflammatory factors. This information used provide theoretical basis for establishment of LPS-induced damage model. The experiment divided into two parts. first part two-factor experimental design determine appropriate incubation time LPS RGR. third-passage BMEC were...
ABSTRACT The mechanism of anthocyanin in alleviating intestine injury pigs is worth pursuing due to the higher similarity physiological structure between human beings and than rodents. Herein, we investigated by which improves gut damage induced with lipopolysaccharide further confirmed this using fecal microbiota transplantation. Thirty‐two piglets were randomly divided into four treatments: control group (Control), model (LPS), prophylactic (An‐LPS), transplantation (FMT‐LPS). results...
Abstract It is well‐recognized that blood flow at branches and bends of arteries generates disturbed shear stress, which plays a crucial in driving atherosclerosis. Flow‐generated fluid stress (FSS), as one the key hemodynamic factors, appreciated for its critical involvement regulating angiogenesis to facilitate wound healing tissue repair. Endothelial cells can directly sense FSS but mechanobiological mechanism by they decode different patterns trigger remains unclear. In current study,...
It is known that physiological overproduction of nitric oxide (NO) contributes to oxidative stress and inflammation. Our published studies indicated vitamin A (VA) reduces NO-induced in bovine mammary epithelial cells (BMECs) by increasing antioxidant enzyme activities. However, the precise mechanism unclear. The present study was conducted examine protective effects VA on damage BMECs vitro using diethylenetriamine (DETA-NO) as NO donor explore intracellular signaling mechanisms involve...
Dioscorea alata L. anthocyanins (DAC) are natural compounds found in plants and have shown potential health benefits. The objective of this investigation was to assess the impact sourced from on growth, carcass traits, antioxidant potential, immune response Hainan black goats. In study, 30 three-month-old goats (with a weight 11.30 ± 0.82 kg) were selected randomly divided into two groups, with 15 each group. During 60-day experiment, control group (CON) treatment were, respectively,...
Increasing findings devote to searching for natural active compositions as additives ameliorate health status. Anthocyanin, water-soluble pigment, has been concerned due its favorable antioxidant activity. In this study, we purified anthocyanin from
Ulcerative colitis (UC) is a kind of inflammatory bowel disease (IBD) that often recurs and difficult to cure, no drugs with few side effects are available treat this disease. LfcinB small molecular peptide obtained by the hydrolysis bovine lactoferrin in digestive tract animals. It has strong antibacterial anti-inflammatory activities. However, direct evidence improves condition mice rarely reported. In study, UC was induced adding 2.5% dextran sulfate (DSS) drinking water orally...
Recently, there has been fast-growing interest among researchers in discovering bioactive peptides from insects and evaluating their potential applications livestock production. The present study aimed to assess the antioxidant properties stability of fly maggot peptide (FMP) its effects on Arbor Acres (AA) broilers’ oxidative stress induced by lipopolysaccharide (LPS) hemocoagulase (HC). A total 108 one-day-old AA broilers were randomly divided into six groups: CG (normal saline, basal...
Nitinol exhibits unique (thermo)mechanical properties that make it central to the design of many medical devices. However, nitinol nominally contains 50 atomic percent nickel, which if released in sufficient quantities, can lead adverse health effects. While nickel release from devices is typically characterized using vitro immersion tests, these evaluations require lengthy time periods. We have explored elevated temperature as a potential method expedite this testing. Nickel was materials...
The considerable increase in oxygen requirements due to the high metabolic rate of bovine mammary epithelial cells (BMEC) during lactation results an augmented production reactive nitrogen species (RNS), such as nitric oxide (NO), which may expose cows increased oxidative stress. Vitamin A (VA) has been shown several studies enhance antioxidant defence system against stress, but whether reason is related a reduced NO remains unclear. Diethylene triamine-nitric polymer (NOp) type...
The present study was conducted to examine the effects of retinoic acid (RA) on synthesis selenoprotein and antioxidative indices bovine mammary epithelial cells (BMEC) in vitro explore mechanisms RA BMEC. subconfluenced BMEC were divided into six treatments with replicates per treatment cultured a Dulbecco's Modified Eagle's Medium/F12 media (10% fetal serum, 5 µg/ml ovine prolactin, 10 ng/ml epidermal growth factor, 1 g/ml hydrocortisone, 0.5% insulin-transferrin-selenium) containing...
The purple tubers of Dioscorea alata L. have been found to contain a variety bioactive chemical components, including anthocyanins, which make it significant investigate the pre-protective effects and its crude extracts on cells prior oxidative stress. To establish suitable damage model, an injured model IPEC-J2 was created using H2O2 as oxidant. Specifically, when concentration 120 μmol/L time 8 h, survival rate decreased approximately 70%, exhibited noticeable stress reaction. Moreover,...
Purpose Polymer fragments have been identified from autopsy reports of patients who had at some point undergone intravascular procedures with medical devices (such as guidewires and catheters) lubricious coatings. Coating separation on these may cause a range adverse events, the most severe being patient death associated undesired embolization blood vessels by coating particles. The objective present study is to identify bench test methods for evaluation hydrophobic hydrophilic coatings...
Introduction The Hainan Dong goat (DG) is a local meat breed widely raised in Hainan, China because of its good adaptability to hot and humid weather. However, the growth rate these DG much slower than that commercialised breeds improved European countries, resulting poor carcase characteristics, including smaller slaughter weight weight, which have become increasingly prominent. In recent decades, Nubian goats been continuously imported into improve production performance breeds. Methods...
Lipopolysaccharides (LPS) are commonly used to construct inflammation models. However, poultry have a certain degree of tolerance LPS due the lack thrombin XI and XII in their bodies. Thrombin activation produces clotting factors that can cleave prothrombin form thrombin. The purpose this study was chick oxidative stress model different concentrations combined with order screen for optimal concentration constructing model, explore effects stimulus on various indicators chicks. Eighty-one...
The objective of this study was to explore how retinoic acid (RA) attenuates oxidative injury induced by hydrogen peroxide (H2O2) in bovine mammary epithelial cells (BMEC). Subconfluence BMEC were randomly divided into four groups with six replicates: the control group (incubated serum-free medium without RA or H2O2 for 30 h), (pre-incubated 24 h RA, then another 6 600 μM H2O2), 1 mg/ml and + (RA prevention group, pre-incubated mM H2O2). results showed that treatment significantly decreased...
All-trans retinoic acid (RA, derivative of vitamin A) has been demonstrated to have anti-oxidative activity and is needed for the proper function immune system. In this study, protective effects RA against lipopolysaccharide (LPS)-induced oxidative stress on bovine mammary epithelial cells (BMECs) investigated. BMECs were divided into four equal groups with six replicates. The first group was used as a control without or LPS. three experimental treated (1 μg/mL) alone, LPS alone plus LPS,...
The current study was conducted to examine the pre-protection effects of vitamin A (VA) on lipopolysaccharide (LPS)-induced oxidative damage in bovine mammary epithelial cells (BMECs) and explore antioxidant mechanisms VA via nuclear factor erythroid 2-related (Nrf2)/nuclear kappa-B (NF-κB)-signalling pathways. BMECs were divided into 10 treatment groups with six replicates per cultured dimethyl sulphoxide (DMSO, vehicle negative control) or 0, 0.05, 0.1, 0.2, 0.5, 1, 2, 3, 4 μg/mL for 24 h...