A5071081840- Additive Manufacturing and 3D Printing Technologies
- Orthopaedic implants and arthroplasty
- Cellular and Composite Structures
- Electrospun Nanofibers in Biomedical Applications
- Polymer composites and self-healing
- Corrosion Behavior and Inhibition
- Shape Memory Alloy Transformations
- Additive Manufacturing Materials and Processes
- Titanium Alloys Microstructure and Properties
- Hydrogen embrittlement and corrosion behaviors in metals
- 3D Printing in Biomedical Research
- Advanced materials and composites
- Bone Tissue Engineering Materials
- Cardiac Structural Anomalies and Repair
- Advanced ceramic materials synthesis
- Anodic Oxide Films and Nanostructures
- Conducting polymers and applications
- Anatomy and Medical Technology
- Orthopedic Infections and Treatments
- Biomedical Ethics and Regulation
- Total Knee Arthroplasty Outcomes
- Carbon Nanotubes in Composites
- Manufacturing Process and Optimization
- Advanced Sensor and Energy Harvesting Materials
- Neurological disorders and treatments
Center for Devices and Radiological Health
2015-2024
United States Food and Drug Administration
2015-2024
Office of Science
2016-2024
Texas A&M University
2017
Louisiana State University Health Sciences Center New Orleans
2017
John Wiley & Sons (United States)
2017
Smith College
2017
Syracuse University
2017
University of Memphis
2017
The University of Texas at Dallas
2013-2015
Additive manufacturing/3D printing of medical devices is becoming more commonplace, a 3D printed drug now commercially available, and bioprinting poised to transition from laboratory market. Despite the variety technologies enabling these products, US Food Drug Administration (FDA) charged with protecting promoting public health by ensuring products are safe effective. To that end, we presenting FDA's current perspective on additive ranging those regulated Center for Devices Radiological...
Shape memory polymer foams have significant potential in biomedical and aerospace applications, but their thermo-mechanical behavior under relevant deformation conditions is not well understood. In this paper we examine the of epoxy shape with an average relative density nearly 20%. These are deformed varying stress, strain, temperature. The glass transition temperature foam was measured to be approximately 90 °C compression tensile tests were performed at temperatures ranging from 25 125...
Single-walled carbon nanotube (SWNT) and other carbon-based coatings are being considered as replacements for indium tin oxide (ITO). The problems of transparent conductors (TCs) from SWNT similar materials include poor mechanical properties, high roughness, low temperature resilience, fast loss conductivity. simultaneous realization these desirable characteristics can be achieved using structural control layer-by-layer (LBL) deposition, which is demonstrated by the assembly hydroethyl...
Colloidal processing was used to make highly dispersed aqueous composite suspensions containing single‐wall carbon nanotubes (SWNTs) and Si 3 N 4 particles. The SWNTs particles were stabilized into using a cationic surfactant at low pH values. Bulk nanocomposites 1.0, 2.0, 6.0 vol% successfully fabricated rapid prototyping. survival of detected, Raman spectroscopy, after high‐temperature sintering, up 1800°C. have densities 97% the theoretical density. engineered nanostructures reveal an...
Shape memory polymer foams are thermally activated using remote induction of magnetic susceptor filler particles dispersed in the thermoset foam matrix. Material properties and performance characterized compared over a range fillers, parameters, packaging configurations. This investigation indicates an improvement heating for increased weight percentage without sacrifice thermo-mechanical up to 10 wt% filler. Detailed analysis results that primary factor improving is heat transfer between...
Spark plasma joining is used to join ZrB 2 –SiC composites with seamless microstructures at the joint that results in retention of high‐temperature mechanical and oxidation properties after joining. Our approach uses a spark sintering furnace Zr–B powder filler layers parts together. The processing parameters optimize microstructure were composition, target temperature, hold time, volume filler. A 1 mm 3 conditions 1800°C for 300 s resulted formation region was indistinguishable from bulk...
In an effort to better understand current test practices and improve nonclinical testing of cardiovascular metallic implants, the Food Drug Administration (FDA) held a public workshop on Cardiovascular Metallic Implants: corrosion, surface characterization, nickel leaching. The following topics were discussed: (1) methods used for corrosion assessments, characterization techniques, leach implant devices, (2) limitations each these in vitro tests predicting vivo performance, (3) need,...
Shape memory polymers (SMPs) are uniquely suited to a number of applications due their shape storage and recovery abilities the wide range available chemistries. However, many desired performance properties tied polymer chemistry which can make optimization difficult. The use foaming techniques is one way tune mechanical response an SMP without changing chemistry. In this work, novel thiol–epoxy was foamed using glass microspheres (40 50% by volume Q-Cel 6019), expandable (1% 930 DU 120),...
Nitinol exhibits unique (thermo)mechanical properties that make it central to the design of many medical devices. However, nitinol nominally contains 50 atomic percent nickel, which if released in sufficient quantities, can lead adverse health effects. While nickel release from devices is typically characterized using vitro immersion tests, these evaluations require lengthy time periods. We have explored elevated temperature as a potential method expedite this testing. Nickel was materials...
Metallic medical devices such as intravascular stents can undergo fretting damage in vivo that might increase their susceptibility to pitting corrosion. As a result, the US Food and Drug Administration has recommended be evaluated for corrosion resistance after have been fatigue tested situations where significant micromotion lead damage. Three common alloys cardiovascular implants are made from [MP35N cobalt chromium (MP35N), electropolished nitinol (EP NiTi), 316LVM stainless steel...
Abstract Corrosion and wear are commonly found at the taper‐trunnion connection of modular total hip arthroplasty (THA) explanted devices. While metal/metal (M/M) connections exhibit more wear/corrosion than ceramic/metal (C/M) connections, damage is present in both, regardless material. This study used a combination assessment techniques including clinical data, visual scoring assessment, optical imaging, profilometry, x‐ray photoelectron microscopy (XPS), to investigate mechanisms features...