A5019389868- Fatty Acid Research and Health
- Coconut Research and Applications
- Antioxidant Activity and Oxidative Stress
- Wound Healing and Treatments
- Burn Injury Management and Outcomes
- Retinoids in leukemia and cellular processes
- Lipid metabolism and biosynthesis
- Cholesterol and Lipid Metabolism
- Taxation and Compliance Studies
- Date Palm Research Studies
- Skin Protection and Aging
- Peroxisome Proliferator-Activated Receptors
- Pomegranate: compositions and health benefits
- Planarian Biology and Electrostimulation
- Polysaccharides Composition and Applications
- Phytochemicals and Antioxidant Activities
- Global Health and Epidemiology
- Allergic Rhinitis and Sensitization
- Pesticide Exposure and Toxicity
- Food Chemistry and Fat Analysis
- Adipose Tissue and Metabolism
- Osteoarthritis Treatment and Mechanisms
- Bee Products Chemical Analysis
- Inflammatory mediators and NSAID effects
- Medicinal Plant Research
Malaysian Palm Oil Board
1999-2024
Cardiff University
2009-2010
This study investigated the effects of vitamins D and E on an insulin-resistant model hypothesized that this treatment would reverse Alzheimer's disease (AD) improves insulin signalling. An was induced in SK-N-SH neuronal cells with a 250 nM re-challenged 100 at two different incubation time (16 h 24 h). The vitamin (10 20 ng/mL), form tocotrienol-rich fraction (TRF) (200 ng/mL) combination signalling markers (IR, PI3K, GLUT3, GLUT4, p-AKT), glucose uptake AD (GSK3β TAU) were determined...
Abstract Palm stearin (POs) and palm kernel olein (PKOo) blends were modified by enzymatic interesterification (IE) to achieve the physical properties of margarine fats. POs PKOo are both products oil industry that presently have limited use. Rhizomucor miehei lipase (Lipozyme IM 60) was used catalyze at 60°C. The progress monitored following changes in triacylglyceride composition. At 60°C can be completed 5 h. Degrees hydrolysis obtained through IE for all decreased from 2.9 2.0 use dry...
The tocotrienol-rich fraction (TRF) from palm oil contains vitamin E, which possesses potent antioxidant and anti-inflammatory activities. Rheumatoid arthritis (RA) is a chronic joint inflammatory disease characterised by severe pain, cartilage destruction, bone erosion owing to the effects of various pro-inflammatory mediators cytokines. Here, we investigated therapeutic TRF in rat model collagen-induced (CIA). Arthritis was induced single intradermal injection collagen type II Dark Agouti...
Synthetic therapeutic drugs for asthma, a chronic airway inflammation characterised by strong eosinophil, mast cell, and lymphocyte infiltration, mucus hyper-production, hyper-responsiveness, exhibit numerous side effects. Alternatively, the high antioxidant potential of palm oil phytonutrients, including vitamin E (tocotrienol-rich fractions; TRF) carotene, may be beneficial alleviating asthma. Here, we determined efficacy TRF, dexamethasone in ovalbumin-challenged allergic asthma Brown...
Palm puree is rich in antioxidants and produced via blending various proportions of mesocarp fibre crude palm oil. The aim this study was to assess the acute subchronic toxicity male female Sprague-Dawley rats. For study, animals administered single palm-puree doses (2000 mg kg-1) by gavage were observed daily for 14 d. rats 500, 1000, or 2000 kg-1 28 We evaluated body organ weights; performed haematological, biochemical, histopathological analyses blood samples during after treatment;...
Background: An experimental study was undertaken to determine the efficacy of epidermal growth factor (EGF) with tocotrienol-rich fraction (TRF) cream in wound-healing process on skin deep partial-thickness burn rats. Methods: A total 180 Sprague-Dawley rats were randomly divided into six groups each and were: untreated control, treated Silverdin® cream, base c% EGF, 3% TRF or EGF TRF, respectively. Creams applied once daily for 21 consecutive days. Six animals from group sacrificed using...
Natural α-tocopherol (α-TCP), but not tocotrienol, is preferentially retained in the human body. α-Tocopherol transfer protein (α-TTP) responsible for binding α-TCP cellular uptake and has high affinity specificity α-tocotrienol. The purpose of this study was to examine modification α-TTP together with other related vitamin E-binding genes (i.e., TTPA, SEC14L2, PI-TPNA) regulating E neuronal cells at rest under oxidative stress. Oxidative stress induced H2O2 an hour which followed by...
Abstract Palm oil is one of the most important edible oils in world. Its composition (rich palmitate and oleate) make it suitable for general food uses but its utility could be increased if fatty acid quality varied. In this study, we have modified a palm olein fraction by transesterification with n‐3 polyunsaturated acids, α‐linolenate or eicosapentaenoic (EPA). Evaluation potential nutritional efficacy was made using chondrocyte culture systems which can used to mimic many degenerative...
Abstract Background Burns are injuries that lie on the skin or other organic tissues caused by exposures to heat, electricity, chemicals ionizing radiation. The present study was carried out record temporal changes in cell population and wound healing-related gene expression rats with deep partial-thickness burn. Methods Burn induced dorsal part of Sprague-Dawley using temperature-regulated 20-mm wide aluminum head heating device. Animals were then sacrificed days three, seven, 11, 14 21...
Our previous study has demonstrated that epidermal growth factor (EGF) with tocotrienol-rich fraction (TRF) cream formulation accelerating postburn wound healing deep partial-thickness burn in rats. Current was conducted to determine the gene expression levels related process. A total of 180 Sprague-Dawley rats were randomly divided into 6 groups: untreated control, treated Silverdin cream, base 0.00075% EGF, 3% TRF or and TRF, respectively. Burn wounds created above-mentioned creams applied...
This study aims to investigate what influences local workers over the age of 40 work and stay employed in oil palm plantations. 414 individuals participated a face-to-face interview that provided study’s primary source data. Exploratory Factor Analysis was used analyse given The revealed factors influencing years leave or continue working plantations can be classified as income factors, internal external factors. factor most significant percentage variance explained by 26.792% Cronbach Alpha...
Oxidative stress is caused by an imbalance between accumulation of reactive oxygen species (ROS) and their elimination. Excessive ROS leads to inflammation that causes many chronic diseases accelerates the aging process. A well-established example age-related macular degeneration (AMD), irreversible eye condition commonly affecting aged population. Carotenoids are antioxidants have demonstrated protective effect in managing AMD. This study determined efficacy carotenes modulating molecular...
Event Abstract Back to ANTI-INFLAMMATORY EFFECT OF PALM TOCOTRIENOL FRACTIONS IN ARTHRITIS Zaida Zainal1*, Sitti Rahma Abdul Hafid1 and Zaizuhana Shahrin1 1 Malaysian Palm Oil Board, Product Development Advisory Services Division, Malaysia Arthritis is an inflammatory joint disease that results in destruction of the articular cartilage. In present study, palm tocotrienol fractions from oil have been shown possess anti-inflammatory effect provided a potential new nutrient for reducing...