A5090309672- Ocular Oncology and Treatments
- Retinopathy of Prematurity Studies
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Neonatal Health and Biochemistry
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Neonatal Respiratory Health Research
- Retinal and Optic Conditions
- Glioma Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Corneal Surgery and Treatments
- Retinal Development and Disorders
- Child Abuse and Related Trauma
- Brain Metastases and Treatment
- Ocular Disorders and Treatments
- Nonmelanoma Skin Cancer Studies
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Hemoglobinopathies and Related Disorders
- Neonatal and fetal brain pathology
- Head and Neck Surgical Oncology
- Corneal surgery and disorders
- Cerebral Venous Sinus Thrombosis
- Syphilis Diagnosis and Treatment
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2011-2025
University of Indonesia
2013-2025
Gates Foundation
2020
Fred Hollows Foundation
2020
Instituto da Visão
2020
Sightsavers
2020
Heidelberg University
2020
Lions Clubs International Foundation
2020
Anglia Ruskin University
2020
Vrije Universiteit Amsterdam
2009
Abstract Retinoblastoma remains incurable in many regions of the world. The major obstacles to cure are delayed diagnosis, poor treatment compliance, and lack evidence‐based recommendations for clinical management. Although enucleation is curative intraocular disease, developing countries retinoblastoma often diagnosed after disease has disseminated beyond eye. A SIOP‐PODC committee generated guidelines management developed a classification system based on resources available those settings....
BackgroundIn 2021, WHO Member States endorsed a global target of 40-percentage-point increase in effective refractive error coverage (eREC; with 6/12 visual acuity threshold) by 2030. This study models and regional estimates eREC as baseline for the initiative.MethodsThe Vision Loss Expert Group analysed data from 565 448 participants 169 population-based eye surveys conducted since 2000 to calculate (met need/[met need + undermet unmet need]). A binary logistic regression model was used...
Following from the publication of International Retinoblastoma Staging System, an open internet discussion group was created at www.cure4kids.org resource. The results a survey distributed among participants are discussed. Although most patients with retinoblastoma were treated under prospective protocols, there wide variation in definition risk criteria and for giving adjuvant chemotherapy following enucleation. Definition high-risk histological features use therapy will be standardized...
Background: Patients who refuse therapy against medical advice may be at risk of adverse health outcomes. We analyzed the impact refusal and its effect on survival retinoblastoma patients. Methods: 165 consecutive untreated patients admitted to CM-Hospital, between 1993–2000 were evaluated retrospectively. Survival outcomes association with delays tumor staging using Kaplan-Meier Cox-Regression. Results: Of cases, 78 cases (47,3%) assigned "No-Refusal-Group"; 52 (31,5%)...
rimary congenital glaucoma (PCG) is an autosomal recessive disease, caused by unknown developmental defect(s) of the trabecular meshwork and anterior chamber angle.It manifests itself clinically during neonatal or infantile period.The disease characterised high intraocular pressure (IOP), buphthalmos with corneal enlargement, breaks in Descemet's membrane. 1wo chromosomal locations for PCG on 2p21 (GLC3A, MIM 231300) 1p36 (GLC3B) have been reported previously. 2 Recently, a third locus...
To determine the anatomical site and patterns of cause blindness in one biggest schools for blind Indonesia with a view to determining potentially preventable treatable causes.165 students school Bandung, Indonesia, were examined clinically data reported using WHO/PBL childhood assessment form.Most (96.4%) (BL); 3% severely visually impaired (SVI). The major causes SVI/BL this study were: (1) corneal staphyloma, scar, phthisis bulbi (mainly attributed infection) 29.7%; (2) retinal...
PurposeTo describe the clinical presentation and treatment outcomes of children diagnosed with retinoblastoma (RB) in year 2017, throughout Asia.DesignMulti-national prospective study including treatment-naïve patients Asia during 2017 followed up thereafter.ParticipantsA total 2112 (2797 eyes) from 96 RB centers 33 Asian countries.InterventionChemotherapy, radiotherapy, enucleation, orbital exenterationMain Outcome MeasuresEnucleation deathResultsWithin cohort, 1021 (48%) were South (SA),...
The purpose of this study was to investigate the clinicopathological features and expression proteins involved in cell proliferation different pathways apoptosis retinoblastoma. Nineteen retinoblastoma patients were included, mitotic index (MI) apoptotic (AI) assessed. MIB‐1, p53, caspase‐3, Bcl‐2, Fas protein assessed by immunohistochemistry. Mann–Whitney U test Fisher's exact used for statistical comparison. High MI (mean 16.84, range 0–66) high MIB‐1 57.89, 0–90) found. significantly...
This article is aimed to review and summarize the indications, outcomes safety profiles regarding use of intravitreal bevacizumab in patients with retinopathy prematurity (ROP) as reported previous studies no intention compare efficacy between laser photocoagulation.Literature search was conducted databases such PubMed, Cochrane, Ovid, Ophthalmology Advance using terms "ROP," "antiangiogenic," "antivascular endothelial growth factor," "intravitreal bevacizumab," "Avastin."Eight prospective...
This study aimed to evaluate bacterial pattern and reduction of colonies in neonatal conjunctivae after prophylaxis 1% chloramphenicol eye ointment 2.5% povidone-iodine ophthalmic solution.
Background Risk factors other than supplemental oxygen might play a role in the development of retinopathy prematurity (ROP). In Indonesia ROP occurs infants up to 34 weeks and 2000 g. for Indonesian NICUs have not been evaluated. Our aim was identify risk use progression preterm Indonesia. Methodology Data on 98 with 77 controls were collected from four two eye centers Jakarta, Indonesia, between 2009 2014. We used multivariate logistic regression analysis determine relationship...
This study aimed to investigate the spectrum of ocular characteristics and viral presence in conjunctival swab patients with COVID-19.In this cross-sectional study, fifty-three were recruited from two COVID-19 referral hospitals Jakarta (Cipto Mangunkusumo Hospital Persahabatan Hospital) July 2020 March 2021. The inclusion criteria who suspected or confirmed cases without symptoms. Demographic data, history exposure, underlying medical condition, systemic symptoms, supporting laboratory...
Abstract Aim To screen for ocular abnormalities in healthy full-term newborn infants using wide-field digital imaging and to analyze factors associated with the findings. Methods A total of 1208 at a tertiary eye hospital (Cipto Mangunkusumo National Referral Hospital) district Jakarta (Koja were enrolled study. All eligible newborns underwent fundus examination within 48 h after birth RetCam shuttle (Natus Medical Incorporated, USA). Retinal findings documented analyzed according obstetric...
Ocular trauma occurring in children often leads to visual impairment or blindness when it is not properly managed. This occurs underdeveloped regions with difficult access professional care at local health facilities. We report a case of post-trauma corneal staphyloma an region eastern Indonesia illustrate the importance proper management ocular areas lacking such expertise and where patients have difficulty accessing even basic care. During community outreach Southwest Sumba, May 2017,...
Aim As data of CT findings for retinoblatoma in Indonesia is not yet available, this study aimed to determine patient distribution and describe RB patients at Cipto Mangunkusumo Hospital. Methods From April 2004 August 2007, scans were performed on 64 new with clinical findings: leukocoria (19 patients), proptosis (41 buphthalmus (2 patients) red eyes patients). The can was using single slice scan multislice axial coronal section. cases categorized into 3 groups: grade I: tumor confined the...
<ns4:p>In this open letter, members of the Global Forum for Research Ethics and Integrity [GFREI] – an open, independent collaborative involving 80+ individuals in 30+ countries report on extend arguments made during a workshop conducted at Oxford Health Bioethics International Conference (June 26–27, 2023). Ten GFREI presenters from nine used case study approach to present discuss emerging model integrate diverse global voices engaging public consultation opportunities sometimes termed...
Background Posterior subcapsular cataracts (PSC) and raised intraocular pressure (IOP) are the most common ocular complications of oral steroid administration, particularly following long-term use or treatment with high doses.
 Objective To evaluate association between cumulative dose duration occurrence PSC IOP, as well its associated factors in children idiopatic nephrotic syndrome (INS).
 Methods This cross-sectional study included aged 4–18 years INS who received therapy for at...
Introduction: Optimal therapeutic approach for extraocular retinoblastoma has not been determined. The prognosis of compared with intraocular remains relatively poor. aim our study is to describe the factors that influence survival rate retinoblastoma. Methods: A retrospective study. Patients diagnosed in Cipto Mangunkusumo Hospital, within 1 January 31 December 2018 were reviewed patient and tumor characteristic, ocular management, survival. Result: During period, a total 80 patients...