A5035613634- Multiple Sclerosis Research Studies
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Peripheral Neuropathies and Disorders
- Ocular Oncology and Treatments
- Glaucoma and retinal disorders
- Cerebral Venous Sinus Thrombosis
- Retinal and Macular Surgery
- Cancer-related Molecular Pathways
- Ophthalmology and Eye Disorders
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Long-Term Effects of COVID-19
- Lymphoma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Head and Neck Surgical Oncology
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Nonmelanoma Skin Cancer Studies
- Natural product bioactivities and synthesis
- Bone health and treatments
- Nephrotoxicity and Medicinal Plants
- Entomological Studies and Ecology
- Bone Metabolism and Diseases
The Affiliated Yongchuan Hospital of Chongqing Medical University
2025
Chongqing Medical University
2025
First Affiliated Hospital of GuangXi Medical University
2014-2024
Guangxi Medical University
2014-2024
Southwest University
2024
China Three Gorges University
2024
Mahidol University
2023
Ramathibodi Hospital
2023
Christie's
2019
Guangxi University
2019
Graves' ophthalmopathy is an inflammatory autoimmune disease of the orbit, characterized by inflammation and proliferation orbital tissue caused CD4+T cells fibroblasts. Despite recent substantial findings regarding its cellular molecular foundations, pathogenesis remains unclear. Accumulating data suggest that microRNAs play important roles in pathophysiology autoimmunity proliferation. Specifically, microRNA-155 (miR-155) can promote enhancing T cell development. In contrast to miR-155,...
BACKGROUND: Preeclampsia is a placenta-origin pregnancy complication. Although its development has long been divided into 2 stages: abnormal placentation (stage I) and the release of factors from hypoperfused placenta circulation, triggering preeclampsia due to endothelial dysfunction II), placenta-derived substances coupling stages remain unclear. METHODS: Extracellular vesicles (EVs) normal preeclampsia-complicated placentas were intravenously administered pregnant mice, blood pressure was...
Purpose: This study aimed to develop an effective nomogram for predicting survival in surgically treated non-small cell lung cancer patients.Methods: We retrospectively evaluated 856 NSCLC this study.Cox regression analyses were performed identify significant prognostic factors developing a predict overall (OS).The discriminative ability was assessed with the concordance index (C-index).Results: On multivariate analysis of cohort, independent CRP, fibrinogen, tumor status, nodal distant...
Abstract Single nucleotide polymorphisms (SNPs) of p53 rs1042522, MDM2 rs2279744 and p21 rs1801270, all in the pathway, which plays a crucial role DNA damage genomic instability, were reported to be associated with cancer risk pathologic characteristics. This case-control study was designed analyse association between these SNPs retinoblastoma (RB) Chinese Han population. These 168 RB patients 185 adult controls genotyped using from venous blood. No significant difference observed allele or...
AIM: To update and investigate the clinical outcomes complications between femtosecond laser-assisted cataract surgery (FLACS) conventional phacoemulsification (CPCS). METHODS: A Meta-analysis was performed using databases, including Pubmed, Embase, Cochrane library. At least one of and/or data in each included randomized controlled trials (RCT) reported. The quality RCT assessed with risk assessments tool. RESULTS: Overall, 25 RCTs 3781 eyes were included. No statistically significant...
To determine whether gypenosides have protective effects in experimental autoimmune optic neuritis (EAON).Mice were randomly divided into seven groups: control group, model three different density monotherapy, methylprednisolone combination of and group. The group was subcutaneously injected with oil emulsion adjuvant all other groups immunized an emulsified mixture myelin oligodendrocyte glycoprotein (MOG) 35-55 peptide to induce EAON. Mice the administered injections daily concentrations...
Background Approximately 30–50% of idiopathic optic neuritis (ION) patients experience one or multiple episodes recurrence. The aim this study was to search for risk factors ION Methods Clinical data on hospitalized diagnosed with between January 2003 and 2011 at the First Affiliated Hospital Guangxi Medical University were retrospectively collected. Univariate multivariate analyses performed that might cause In total, 115 cases (32 recurrent 83 non-recurrent cases) complete analyzed. length...
Quantitative measurement of the orbital soft tissue volume plays a very important role in study diseases. The purpose this is to establish computed tomography- (CT-) based three-dimensional (3D) reconstruction model and measure Chinese adults. We collected data from 103 adults (52 males 51 females) who underwent CT. CT images these were used reconstruct 3D bony cavity, fat, extraocular muscle, intraorbital optic nerve using Mimics software, their respective volumes measured. mean (±SD)...
Thyroid-associated ophthalmopathy is the commonest orbital disease in adults. However, shortcomings still exist treatments. The aim of this study was to identify efficacy and potential mechanism gypenosides treatment thyroid-associated ophthalmopathy. Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform screened for active compounds gypenosides, targets were predicted using Swiss Target Prediction. obtained from Online Mendelian Inheritance Man, Comparative...
Purpose: Dysthyroid optic neuropathy (DON) is the most severe condition in thyroid eye disease (TED); however, no study has been conducted to assess quality of life these patients date. The aim this was evaluate vision-related TED with DON using a Chinese version 25-item National Eye Institute Visual Function Questionnaire (CHI-VFQ-25).Methods: CHI-VFQ-25 scores were compared for 23 and 13 without DON. correlations between clinical characteristics subscale on floor ceiling effects also...
The aim of this cross-sectional study is to evaluate vision-related quality life (VRQoL) and depression in patients with rhegmatogenous retinal detachment (RRD).The VRQoL were evaluated 58 unilateral RRD healthy controls, using the Chinese version National Eye Institute Visual Function Questionnaire (CHI-VFQ-25) Beck Depression Inventory-II, respectively.Composite scores CHI-VFQ-25 significantly lower patients, compared controls (P < .001). Lower composite associated older age .01), severer...
PurposeTo describe the clinical presentation and treatment outcomes of children diagnosed with retinoblastoma (RB) in year 2017, throughout Asia.DesignMulti-national prospective study including treatment-naïve patients Asia during 2017 followed up thereafter.ParticipantsA total 2112 (2797 eyes) from 96 RB centers 33 Asian countries.InterventionChemotherapy, radiotherapy, enucleation, orbital exenterationMain Outcome MeasuresEnucleation deathResultsWithin cohort, 1021 (48%) were South (SA),...
The present study aimed to develop a prediction model for predicting developing debilities after optic neuritis.
Abstract In this study, we try to explore the effect of orbital decompression treatment on severe dysthyroid optic neuropathy. We retrospectively collected demographic and clinical characteristics thyroid eye disease patients who performed decompression. Then analyzed change best-corrected visual acuity exophthalmometry after surgery correlations among parameters. A total 22 cases (30 eyes) were included in study. After decompression, acuities improved 16 eyes, declined 8 had no 5 eyes....
Purpose. To observe the long-term effectiveness of scleral buckling and transscleral cryopexy conducted under a surgical microscope in treatment uncomplicated rhegmatogenous retinal detachment. Methods. This was retrospective analysis total 227 consecutive patients (244 eyes) with detachment (proliferative vitreoretinopathy ≤ C2). All underwent without using binocular indirect ophthalmoscope or contact lens. Results. After initial surgery, complete reattachment achieved 226 eyes (92.6%),...
Background/aim: The aim of this study was to investigate the potential correlation between clinical characteristics and prognosis patients with retinoblastoma (Rb). Materials methods: This retrospective included 314 Rb patients. Clinical data including laterality eyes, sex, age, presenting signs, lag time, survival were recorded analyzed. Results: Leukocoria is most common presentation Rb. Patients isolated leukocoria had shorter time exhibited a high rate (85%, 5 years). strabismus blurred...
This study aimed to report the visual acuity outcomes and complications of sutured scleral fixation posterior chamber intraocular lens (IOL) in children under 9 years old with congenital ectopia lentis.Twenty-six (47 eyes) lentis were included this study. The mean age at surgery was 61.6 ± 22.3 months (range, 32-94). Patients underwent extraction, anterior vitrectomy, IOL. implanted IOL rigid polymethyl methacrylate (PMMA) (CZ70BD, n = 36) foldable (SA60AT, 9, LI61SE, 2). outcome measures...