Background: Many studies have shown the prognostic value of inflammation based factors in different cancers.This work aimed to explore pretreatment C-reactive protein/albumin (CRP/Alb) ratio patients with cervical cancer, and compared other inflammatory factors, such as neutrophil/lymphocyte ratio(NLR), Glasgow score (mGPS), index (PI), platelet/lymphocyte (PLR), nutritional (PNI), clinicopathological parameter squamous cell carcinoma antigen (SCC-Ag).Methods: This study was a retrospective...

The level of anine aminotransferase/aspartate aminotransferase (ALT/AST) ratio in the serum was often used to assess liver injury. Whether ALT/AST (LSR) associated with prognosis for gastric adenocarcinoma (GA) has not been reported literature. Our aim investigate prognostic value preoperative LSR patients GA. A retrospective study performed 231 GA undergoing curative resection. medical records collected include clinical information and laboratory results. We investigated correlations...

Purpose: This study aimed to develop an effective nomogram for predicting survival in surgically treated non-small cell lung cancer patients.Methods: We retrospectively evaluated 856 NSCLC this study.Cox regression analyses were performed identify significant prognostic factors developing a predict overall (OS).The discriminative ability was assessed with the concordance index (C-index).Results: On multivariate analysis of cohort, independent CRP, fibrinogen, tumor status, nodal distant...

The purpose of this work is to analyze preoperative serum aspartate aminotransferase (AST) levels and their effect on the prognosis patients with non-small cell lung cancer (NSCLC) after surgical operation. These analyses were performed retrospectively in NSCLC followed by surgery; participants recruited between January 2004 2008. All clinical information laboratory results collected from medical records. We explored association AST recurrence-free survival (RFS), overall (OS) patients....

This study aimed to establish an effective predictive nomogram for non-small cell lung cancer (NSCLC) patients with chronic hepatitis B viral (HBV) infection. The was based on a retrospective of 230 NSCLC HBV accuracy and discriminative ability the were determined by concordance index (C-index), calibration plot decision curve analysis compared current tumor, node, metastasis (TNM) staging system. Independent factors derived from Kaplan–Meier primary cohort predict overall survival (OS) all...

Recent studies have indicated that inflammation-based prognostic scores, such as the Glasgow Prognostic Score (GPS), modified GPS (mGPS) and C-reactive protein/Albumin (CRP/Alb) ratio, platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte (NLR), been reported to value in patients with many types of cancer, including nasopharyngeal carcinoma (NPC). In this study, we proposed a novel stage, named I for NPC. A retrospective study 409 newly-diagnosed cases NPC was conducted. The factors (GPS,...

Despite recent advances in the treatments of hepatocellular carcinoma (HCC), prognosis HCC patients remains controversial. The purpose this study was to investigate prognostic performance pretreatment albumin C-reactive protein ratio (ACR) with HCC.This included 409 initially diagnosed retrospectively. optimal cut-off points for distinguishing high and low ACR value determined by X-tile software. chi-squared test used comparing baseline clinicopathologic parameters different groups...

Human bocavirus (HBoV) is a novel parvovirus associated with respiratory tract diseases and gastrointestinal illness in adult pediatric patients throughout the world. To investigate epidemiological genetic variation of HBoV Guangzhou, South China, we screened 3460 throat swab samples from 1686 children 1774 adults acute infection symptoms for between March 2010 February 2011, analyzed complete genome sequence 2 strains. Specimens were by real-time PCR other 6 common viruses RT-PCR or PCR....

Objective: To explore the prognostic significance of inflammatory indicator, neutrophil to lymphocyte ratio (NLR) and platelet (PLR), for advanced-stage diffuse large B-cell lymphoma (DLBCL). Methods: The data advanced stage DLBCL cases was retrospectively collected, all patients were seen from January 2006 December 2012 in National Cancer Center/Cancer Hospital, Chinese Academy Medical Sciences. divided into low NLR group (≤5∶1) high (>5∶1); PLR (≤300∶1) (>300∶1). Kaplan-Meier method used...

Abstract Background This study aimed to establish and validate a novel clinical model differentiate between benign malignant solitary pulmonary nodules (SPNs). Methods Records from 295 patients with SPNs in Sun Yat-sen University Cancer Center were retrospectively reviewed. The prediction was established using LASSO logistic regression analysis by integrating features, radiologic characteristics laboratory test data, the calibration of analyzed Hosmer-Lemeshow (HL test). Subsequently,...

To establish and validate a multi-parametric prognostic model based on clinical features serological markers to estimate the overall survival (OS) in non-small cell lung cancer (NSCLC) patients with chronic hepatitis B viral (HBV) infection.The was established by using Lasso regression analysis training cohort. The incremental predictive value of compared traditional TNM staging treatment for individualized evaluated concordance index (C-index), time-dependent ROC (tdROC) curve, decision...

We aim to estimate the prevalence of baseline clinically significant distress in Chinese patients with head and neck squamous cell carcinoma (HNSCC) before receiving first radiotherapy assess factors predictive distress. One hundred sixty-eight were enrolled complete a set questionnaires including Distress Thermometer (DT) Hospital Anxiety Depression Scale (HADS). Of these, 131 available for final analysis. The accuracy DT was validated using HADS as gold standard, receiver operating...

Abstract features and serological markers to estimate overall survival (OS) in non-small cell lung cancer (NSCLC) patients with chronic hepatitis B viral (HBV) infection. Methods: The prognostic model was generated by using Lasso regression training cohort. incremental predictive value of the traditional TNM staging clinical treatment for individualized evaluated concordance index (C-index), time-dependent ROC (tdROC), decision curve analysis (DCA). A risk score nomogram OS built combining...

Objective: To analyze the clinical characteristics and prognosis of newly diagnosed localized head neck rhabdomyosarcoma. Methods: Cases rhabdomyosarcoma between January 2006 December 2016 were analyzed retrospectively. The features patients described. Kaplan-Meier method was used to survival rate under different combined modality therapy with or without chemotherapy. prognostic factors by Cox model. Results: A total 46 included in this study. Among them, median follow-up time 77 months...

Background: This study aimed to establish and validate a novel clinical model differentiate between benign malignant solitary pulmonary nodules (SPNs).Methods: Records from 406 patients with SPNs in Sun Yat-sen University Cancer Center were retrospectively reviewed. The data was randomly divided into training cohort internal validation cohort. Other 190 Henan Tumor Hospital used for external validation. prediction established using LASSO logistic regression analysis by integrating features,...

Abstract Background To develop and validate a multi-parametric prognostic model based on clinical features serological markers to estimate overall survival (OS) in non-small cell lung cancer (NSCLC) patients with chronic hepatitis B viral (HBV) infection. Methods The was generated by using Lasso regression training cohort. incremental predictive value of the traditional TNM staging treatment for individualized evaluated concordance index (C-index), time-dependent ROC (tdROC), decision curve...

Objective To investigate the efficacy of combined hyperfractionated radiation therapy (HFX RT) plus accelerated HFX RT and concomitant chemotherapy (CHT) in stage ⅢA or ⅢB non-small-cell lung cancer (NSCLC) compared with alone. Methods From August 1998 to December 2001, 56 patients NSCLC were randomized into following groups: alone group (group Ⅰ, n=28), 1.2 Gy twice daily a total dose 45.6 Gy, followed by 1.6 daily, planned was 68.0 tumour; RT/CHT Ⅱ, same CHT consisting 20 mg/m2 cisplatin...