A5047264604- Ocular Oncology and Treatments
- Brain Metastases and Treatment
- Retinopathy of Prematurity Studies
- Corneal Surgery and Treatments
- Nonmelanoma Skin Cancer Studies
- Retinal and Macular Surgery
- Cancer-related Molecular Pathways
- Retinal Diseases and Treatments
- Neonatal Health and Biochemistry
- Neonatal Respiratory Health Research
- Glioma Diagnosis and Treatment
- Virus-based gene therapy research
- Ear and Head Tumors
- Glaucoma and retinal disorders
- Cell Adhesion Molecules Research
- Cancer Research and Treatments
- Vascular Tumors and Angiosarcomas
- Prostate Cancer Treatment and Research
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Head and Neck Surgical Oncology
- Neuroblastoma Research and Treatments
- Retinal Development and Disorders
- Nasolacrimal Duct Obstruction Treatments
- Genomics and Rare Diseases
XinHua Hospital
2016-2025
Shanghai Jiao Tong University
2016-2025
Russian Medical Academy of Continuous Professional Education
2024
Shanghai Municipal Education Commission
2013
Shanghai First People's Hospital
2009
To analyze the incidence and severity of retinopathy prematurity (ROP) in China, to explore workload implications applying different criteria.A prospective, neonatal units-based study undertaken two tertiary level hospitals Shanghai, from January 1, 2010 December 31, 2012. All infants with birth weight (BW) 2000 g or less and/or gestational age (GA) 34 weeks were screened for ROP. Retinopathy was classified using international classification, treated accordance recommendations Early...
Purpose: To investigate timing and risk factors of recurrent retinopathy prematurity (ROP) after intravitreal ranibizumab (IVR) monotherapy. Methods: Fifty eyes (the more severe eye) 50 infants treated with IVR monotherapy for type 1 ROP were studied retrospectively. The mean follow-up time was 31 weeks IVR. Recurrent (recurrence extraretinal fibrovascular proliferation [EFP]) determined by RetCam wide-angle fundus imaging binocular indirect ophthalmoscopy. Risk recurrence estimated...
The risk of extraocular extension from injecting chemotherapy into eyes with retinoblastoma is minimally understood; however, understanding this important because the increasing use intravitreous chemotherapy.To evaluate in that have received injections.This retrospective cohort study was performed 655 patients at 10 centers North and South American, European, Israeli, Chinese centers. Physicians administered more than 120 injections February 1, 1999, through 28, 2017.Risk secondary...
Background/aims Ophthalmic artery chemosurgery (OAC) has changed the face of retinoblastoma treatment and led to a higher rate globe salvage. The introduction intravitreal chemotherapy (IVitC) further enhanced salvage with increased success in seeds. Our group seen at treating non-vitreous disease that is refractory OAC using IVitC. This study was undertaken quantify report on this success. Methods A retrospective review used identify patients treated IVitC for indications other than...
The aim of this study is to examine the burden family caregivers patients with retinoblastoma in China and relationships between depression, caregiver social support. A descriptive correlational survey was conducted 117 Chinese outpatient from Department Ophthalmology a tertiary hospital Shanghai, China. Family were asked respond four questionnaires including sociodemographic questionnaire, Becker Depression Inventory, Caregiver Burden Inventory Social Support Rating Scale. incidence...
High-risk histopathologic features of retinoblastoma are useful to assess the risk systemic metastasis. In this era globe salvage treatments for retinoblastoma, definition high-risk is evolving.To evaluate variations in metastasis different ocular oncology practices around world.An electronic web-based, nonvalidated 10-question survey was sent December 2020 52 oncologists and pathologists treating at referral centers.Anonymized about retinoblastoma.High-risk that determine further treatment...
Background: The relationship between lag time and outcomes in retinoblastoma (RB) is unclear. In this study, we aimed to study the effect of onset symptoms diagnosis countries based on their national-income analyse its outcomes. Methods: We performed a prospective 692 patients from 11 RB centres 10 1 January 2019 31 December 2019. Results: following factors were significantly different among level: age at (p = 0.001), distance home nearest primary healthcare centre 0.03) mean detection first...
Purpose To present the clinical characteristics and management outcomes of Coats disease with retinoschisis (retinal cyst). Methods This was a retrospective review 13 eyes from consecutive patients retinal cyst. Clinical findings multimodal ophthalmic imaging were recorded to characterize cyst in disease. All initially treated endolaser photocoagulation combined external drainage cystic fluid intravitreal ranibizumab injection. Patients subsequently followed up analyze anatomic visual...
To evaluate the effect of lag time between diagnosis retinoblastoma (RB) and treatment in patients from 10 countries. Prospective study 692 treatment-naïve RB countries followed up for 3 years recruitment. The mean onset first symptom to visit center was 150 days. follow-up duration 26 months (median, 32 months; range, <1-51 months). A higher socioeconomic status country associated with a lower risk enucleation: Lower-middle-income vs. low-income (p<.001), Upper-middle-income (p = .009),...
Abstract Purpose Early detection of ocular abnormalities in newborns is essential for timely diagnosis and treatment. This study aimed to assess the 1‐year result a multicentre prospective neonatal eye examination programme with wide‐field digital imaging system China. Methods A collaborative group screening was established nine hospitals, including eight Maternal Children's Hospitals, one general hospital across China from July 2016 June 2017. Ocular examinations were performed on within 28...
To investigate in a large global sample of patients with retinoblastoma whether sex predilection exists for this childhood eye cancer.A cross-sectional analysis including 4351 treatment-naive from 153 countries who presented to 278 treatment centers across the world 2017. The ratio (male/female) was compared at birth by means two-sided proportions test level, country economic grouping, continent, and selected countries.For entire sample, mean ratio, 1.20, higher than weighted birth, 1.07 (p...
Purpose . To evaluate the efficacy of intravitreal melphalan for vitreous seeds from retinoblastoma in Chinese patients. Methods This is a retrospective review 17 consecutive patients (19 eyes) with viable retinoblastoma. The received multiple injections 20 ug melphalan. Results International Classification Retinoblastoma groups were B 1 eye, C 5 eyes, D 11 and E 2 eyes. On average, 6 (range: 1–15) given to each eye at interval 2–4 weeks. Successful control was achieved 16 19 eyes (84.21%)....
Purpose.: To establish human retinoblastoma (RB) animal models that allow sensitive, noninvasive and continuous monitoring of tumor growth metastasis in vivo. Methods.: The RB cell lines HXO-Rb44 Y79 were engineered to express a fusion reporter gene allowing for bioluminescence fluorescence imaging. Intraocular metastatic tumors induced immunodeficient nude mice by injection bioluminescent cells into eye compartments the left ventricle or tail vein. kinetics intraocular was quantitatively...
The aim of the study was to analyze clinical characteristics pediatric patients with ocular toxocariasis.Ocular toxocariasis diagnosed and treated in 46 children from Shanghai surrounding provinces. diagnosis confirmed immunologically by performing an enzyme-linked immunosorbent assay on serum and/or intraocular fluid. All their guardians completed a questionnaire concerning cases living habits.The mean age onset 6 ± 3 years. Most (85%) resided rural areas, 91% had contact adult dogs or...
Type 1 retinopathy of prematurity (ROP) is occasionally observed in preterm infants after the postmenstrual age (PMA) 40 weeks; however, evidence-based treatment guidelines are largely lacking. In this study, we report clinical characteristics with type ROP at PMA > weeks and compare outcomes intravitreal ranibizumab (IVR) laser therapy.Twenty-seven eyes 14 infants, primarily treated for by IVR (17 9 infants) or photocoagulation (10 5 were included retrospective analysis. The preoperative...
// Shuxian Chen 1, * , Xunda Ji 2, Ming Liu 1 Zhengrong Xia Hui Zheng Qiufeng Yin He Wang 3 Yuhua Li Department of Radiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School Medicine, 200092, China 2 Ophthalmology, Institute Science and Technology for Brain-Inspired Intelligence, Fudan University, 200433, These authors have contributed equally this work Correspondence to: Li, email: liyuhua10@sina.com Wang, hewang@fudan.edu.cn Keywords: retinoblastoma, intra-arterial...