A5022850345- Child Nutrition and Water Access
- Food Security and Health in Diverse Populations
- Viral Infections and Vectors
- Viral gastroenteritis research and epidemiology
- Iron Metabolism and Disorders
- Mycobacterium research and diagnosis
- Advanced biosensing and bioanalysis techniques
- Plant-Microbe Interactions and Immunity
- Cocoa and Sweet Potato Agronomy
- Indigenous Health and Education
- Pneumocystis jirovecii pneumonia detection and treatment
- Gut microbiota and health
- Bacteriophages and microbial interactions
- Tuberculosis Research and Epidemiology
- Mosquito-borne diseases and control
- RNA and protein synthesis mechanisms
- Leptospirosis research and findings
- COVID-19 epidemiological studies
- Reproductive tract infections research
- Biochemical and biochemical processes
University of Michigan
2015-2024
Escuela Superior Politecnica del Litoral
2021
Michigan State University
2020
Universidad San Francisco de Quito
1969-2015
Northern Arizona University
2015
Instituto Nacional de Investigación en Salud Pública
2015
Royal Tropical Institute
2015
Leptospira spp., which comprise 3 clusters (pathogenic, saprophytic, and intermediate) that vary in pathogenicity, infect >1 million persons worldwide each year. The disease burden of the intermediate leptospires is unclear. To increase knowledge this cluster, we used new molecular approaches to characterize spp. 464 samples from febrile patients rural, semiurban, urban communities Ecuador; 20 nonfebrile rural community; 206 animals semiurban community. We observed a higher percentage...
Perinatal factors can shape fecal microbiome patterns among pregnant women and their infants. However, there is scarce information about the effect of maternal demographics perinatal exposures on antibiotic resistance genes (ARG) mobile genetic element (MGE) in We examined samples from during third trimester pregnancy (n = 51) 6-month-old infants 40). Of 91 participants, 72 represented 36 maternal-infant dyads, 15 were additional women, 4 assessed effects demographics, pre-pregnancy BMI,...
Ecuador is responsible for up to 70 % of the world's production fine flavor cocoa. Although fungal diseases have reduced cocoa production, eco–friendly alternatives been implemented control spread phytopathogens. This study aimed explore potential endophytic strains isolated from Nacional trees synthetize compounds with antimicrobial and surface active properties. It was determined that under in vitro conditions, seven (DS03, DS07, DS18, DS23, DS31, DS34 DS50) exhibited antifungal activity...
Enteropathogens are major contributors to mortality and morbidity, particularly in settings with limited access water, sanitation, hygiene infrastructure. To assess transmission pathways associated enteropathogen infection, we measured household environmental conditions assayed 22 enteropathogens using TaqMan Array Cards stool samples from 276 six-month-old children living communities along a rural-urban gradient Northern Ecuador. We utilized multivariable models, risk factor importance,...
Background Anemia is a condition characterized by decline in the number of functional red blood cells or hemoglobin. Women reproductive age from low- and middle-income countries are at higher risk anemia, which could lead to prenatal, obstetric perinatal complications. The aim our study was explore associations between anemia status set demographic, socio-economic factors, among Ecuadorian women (WRA). Methods We used data non-pregnant, WRA (≥12 ≤49 years) enrolled nationally representative...
ABSTRACT. The relative importance of environmental pathways that results in enteropathogen transmission may vary by context. However, measurement contact events between individuals and the environment remains a challenge, especially for infants young children who use their mouth hands to explore environment. Using mixed-method approach, we combined 1) semistructured observations characterize key behaviors associated with enteric pathogen exposure 2) structured using Livetrak, customized...
Abstract The Zika virus (ZIKV) epidemic in Latin America (2015–2016) has primarily been studied urban centers, with less understanding of its impact on smaller rural communities. To address this gap, we analyzed ZIKV seroepidemiology 6 Ecuadorian communities (2018–2019) varying access to a commercial hub. Seroprevalence ranged from 19% 54%, measured by nonstructural protein 1 blockade binding enzyme-linked immunosorbent assay. We observed decline seroprevalence between 2018 and 2019 that was...
Abstract Background US hematopoietic cell transplantation (HCT) recipients have a low prevalence of latent tuberculosis infection (LTBI), but if latently infected they are at risk for progression to active tuberculosis. At our center, all HCT underwent LTBI testing pretransplant by tuberculin skin (TST) until 2013 when we implemented targeted screening program. Our objective was assess the utility program that incorporated questionnaire target TST and QuantiFERON TB Gold (QFT) testing....
La fabricación de nanoestructuras a partir biomoléculas como fibras ADN es una frontera en continua exploración gracias multitud aplicaciones potenciales sistemas biológicos complejos. Las secuencias analizadas se encuentran orígenes replicación virus y bacterias. En este artículo reporta la caracterización detallada nivel atómico rico Guaninas que forman estructuras cremallera. Para esto utilizaron métodos modelación con mecánica molecular. Se construyeron modelos para las minimizaron, lo...