A5061386610- Gut microbiota and health
- Infant Nutrition and Health
- Birth, Development, and Health
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Breastfeeding Practices and Influences
- Viral gastroenteritis research and epidemiology
- Food Allergy and Anaphylaxis Research
- Child Nutrition and Water Access
- Food Security and Health in Diverse Populations
- Gestational Diabetes Research and Management
- Maternal Mental Health During Pregnancy and Postpartum
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Colorectal Cancer Screening and Detection
- Neonatal Respiratory Health Research
- Digestive system and related health
- Genetic factors in colorectal cancer
- Fatty Acid Research and Health
- Diet and metabolism studies
- Urinary Tract Infections Management
- Pelvic floor disorders treatments
- Pediatric health and respiratory diseases
- Immune Cell Function and Interaction
- Adolescent and Pediatric Healthcare
Michigan State University
2016-2025
University of Michigan
2022
Michigan United
2014-2018
University of Illinois Urbana-Champaign
2010-2017
University of California, Davis
2003-2016
Urbana University
2010-2014
Goodwin College
2013
Florida State University
2008
University of Chicago
2004
Abstract Oral microbiome dysbiosis has been associated with various local and systemic human diseases such as dental caries, periodontal disease, obesity, cardiovascular disease. Bacterial composition may be affected by age, oral health, diet, geography, although information about the natural variation found in general public is still lacking. In this study, citizen-scientists used a crowdsourcing model to obtain bacterial data from guests at Denver Museum of Nature & Science determine...
Human milk (HM) is rich in oligosaccharides (HMO) that exert prebiotic and anti-infective activities. HM feeding reduces the incidence of rotavirus (RV) infection infants. Herein, anti-RV activity was tested an established vitro system for assessing cellular binding viral infectivity/replication, also a newly developed, acute RV infection, situ piglet model. For work, crude HMO isolated from pooled HM, neutral (lacto- N -neotetraose, LNnT; 2′-fucosyllactose) acidic (aHMO, 3′-sialyllactose,...
Background About 25% of women in the United States are obese prior to becoming pregnant. Although there is some knowledge about relationship between gastrointestinal microbiota and obesity, little known pre-pregnancy obesity pregnancy or its impact on infant gut microbiota. However, composition early life may influence childhood health. Thus, objective this research was identify associations maternal (n = 39) infancy microbiotas. Results Fecal bacterial communities from overweight had lower...
Importance Limited access to healthy foods, resulting from residence in neighborhoods with low food access, is a public health concern. The contribution of this exposure early life child obesity remains uncertain. Objective To examine associations neighborhood during pregnancy or childhood body mass index (BMI) and risk. Design, Setting, Participants Data cohorts participating the US nationwide Environmental Influences on Child Health Outcomes consortium between January 1, 1994, March 31,...
To cite this article: Maleki SJ, Teuber SS, Cheng H, Chen D, Comstock Ruan S, Schein CH. Computationally predicted IgE epitopes of walnut allergens contribute to cross-reactivity with peanuts. Allergy 2011; 66: 1522–1529. Background: Cross-reactivity between peanuts and tree nuts implies that similar immunoglobulin E (IgE) are present in their proteins. Objective: determine whether sequences known peanut IgE-binding sequences, according the property distance (PD) scale implemented Structural...
Background Obesity increases the risk of colon cancer. It is also known that most colorectal cancers develop from adenomatous polyps. However, effects obesity and adipokines on colonic polyp formation are unknown. Methods To determine if BMI, waist circumference or associated with polyps in males, 126 asymptomatic men (48–65 yr) were recruited at time colonoscopy, anthropometric measures as well blood collected. Odds ratios determined using polytomous logistic regression for number (0 ≥3)...
Allergy to walnut is the most frequently reported tree nut allergy in United States. Walnut 2S albumin, a vicilin-like protein, and lipid transfer protein allergen have previously been described. Our objective was clone express cDNA encoding legumin group assess IgE-binding with sera from allergic patients, investigate cross-reactivity selected nuts. Primers were used obtain by 5' 3' rapid amplification of ends mRNA. The subcloned into pMAL-c2X vector recombinant fusion named rJug r 4,...
Infant formulas lack the complex mixture of oligosaccharides found in human milk. These milk (HMO) may be pivotal to development neonatal immune system. Few comprehensive analyses effects HMO on cells from neonates have been undertaken. Herein, direct were analysed ex vivo . Peripheral blood mononuclear (PBMC) isolated 10-d-old sow-reared (SR) or colostrum-deprived formula-fed (FF) pigs stimulated for 72 h with single HMO, mixtures a (iHMO). T-cell phenotype, cytokine production and...
Because microbes use carotenoids as an antioxidant for protection, dietary could be associated with gut microbiota composition. We aimed to determine associations among reported carotenoid intake, plasma concentrations, and fecal bacterial communities in pregnant women. Pregnant women (n = 27) were enrolled a two-arm study designed assess feasibility of biospecimen collection delivery practical nutrition intervention. Plasma samples collected surveyed 24-hr checklist recalls. analyzed by...
OBJECTIVES Breastfeeding practices may protect against offspring obesity, but this relationship is understudied among women with obesity. We describe the associations between breastfeeding and child BMI for age z-score (BMIz), stratified by maternal BMI. METHODS analyzed 8134 dyads from 21 cohorts in Environmental Influences on Child Health Outcomes Program. Dyads data pre-pregnancy BMI, infant feeding practices, ≥1 assessment ages of 2 6 years were included. The continuous BMIz assessed...
Movement disorders may vary with the time of day and mental state. Despite hypothalamic control biological timing, we discuss how many cell populations throughout brain body, including dopaminergic nuclei, likely have time-keeping functions. We provide a “primer” movement significant variation in or presentation state altered consciousness. Parkinsonism illustrates our overall argument. Patients an idiopathic behavioral motoric disorder sleep develop parkinsonism eventually, at high...
Summary The role of the liver in initiation and maintenance tolerance is a critical immune function that involves multiple lineages cells. Included within these populations are dendritic cells (DCs). Although there has been significant work on phenotypic functional roles splenic bone marrow cells, as well their subsets, comparable studies have often difficult. To address this issue we isolated, from C57BL/6 mice, relatively pure DCs compared phenotype to data spleen using flow cytometry,...
Peanut allergy continues to be a problem in most developed countries of the world. We sought processing method that would alter allergenic peanut proteins, such allergen recognition by IgE from allergic individuals significantly reduced or eliminated. Such render accidental exposures trace amounts peanuts safer. A combination boiling and frying decreased recovery Ara h 1 2 at their expected MWs. In contrast, treatment with high pressures under varying temperatures had no effect on protein...
Abstract Background: Altered lipid metabolism and plasma fatty acid (FA) levels are associated with colorectal cancer. Obesity elevated waist circumference (WC) increase the likelihood of developing precancerous colon adenomas. Methods: Venous blood was collected from 126 males, ages 48 to 65 years, who received routine colonoscopies. Plasma phospholipid (PPL) FAs were isolated, derivatized, then analyzed using gas chromatography. ORs 95% confidence intervals determined polytomous logistic...