A5019789364- Breast Cancer Treatment Studies
- Liver Disease Diagnosis and Treatment
- Drug Solubulity and Delivery Systems
- Cancer Treatment and Pharmacology
- Cancer Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Nanoparticle-Based Drug Delivery
- MicroRNA in disease regulation
- Hepatocellular Carcinoma Treatment and Prognosis
- Nonmelanoma Skin Cancer Studies
- Advanced Drug Delivery Systems
- Advanced Breast Cancer Therapies
- Lipid metabolism and disorders
- Phytochemicals and Medicinal Plants
- Pharmacological Effects and Toxicity Studies
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Pancreatic function and diabetes
- Proteoglycans and glycosaminoglycans research
- Ear and Head Tumors
- Pharmacogenetics and Drug Metabolism
- Glioma Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Galectins and Cancer Biology
- Liver physiology and pathology
Sohag University
2013-2023
Alexandria University
1995-1996
University of Georgia
1988-1993
Lung Cancer (LC) is a major cancer killer worldwide, and 5-yr survival extremely poor (≤15%), accentuating the need for more effective diagnostic therapeutic strategies. Studies have shown cell-free microRNAs (miRNAs) circulating in serum plasma with specific expression cancer, indicating potential of using miRNAs as biomarkers diagnosis therapy. This study aimed to identify differentially-expressed two Non-Small Cell (NSCLC) patients that might be clinically useful tool lung early...
A magnetic cationic microsphere delivery system, prepared from the polysaccharide chitosan and containing oxantrazole (OX), was examined for its ability to enhance brain of OX compared administration in solution (OX-S). Magnetic microspheres (MCM-OX) OX-S were administered intraarterially male Fischer 344 rats at doses 0.1 mg/kg 0.5 with a field 6000 G applied 30 min. Animals sacrificed min 120 after MCM-OX treatments, multiple tissues collected analyzed by HPLC. statistical analysis effects...
Background: Lung cancer is one of the main human health threats. Survival lung patients depends on timely detection and diagnosis. Among genetic irregularities that control development progression, there are microRNAs (miRNAs). This study aimed to assess plasma level circulating miRNA-17 miRNA-222 as non-invasive markers in non-small-cell (NSCLC) patients. Patients methods: A total 40 with NSCLC 20 healthy controls who were matched terms age sex patient group included this case-control...
This study was designed to investigate the potential of Physalis peruviana root as a functional food with hepato-renal protective effects against fibrosis. The chemical composition plant suggested presence alkaloids, withanolides and flavonoids. Five compounds were isolated their structures elucidated by different spectral analysis techniques. One compound from roots: cuscohygrine. biological evaluation conducted on animal groups; control rats, treated ethanolic extract, CCl4 group,...
Abstract The clinical outcome of lymphocytic leukemia (CLL) is quite heterogeneous. purpose this observational study was to investigate the merit measuring plasma galectin-9 and CXCL-13 concentrations as predictors CLL activity, prognosis, early indicators therapeutic response. These biomarkers were compared with other prognostic indicators, progression-free survival (PFS), time first treatment (TTT), overall (OS) over a follow-up period (4 years). First, analyzed in patients at diagnosis...
a total of (100) alkalineurine were obtained from patient suffering urinary tract infection both sexes attended to Al- Hilla surgery Teaching Hospital during period September 2016 December in Al-Hilla province. It was found that (23) P. mirabilis isolates recovered where 14(60%) isolated with complicated and 9 (39%) patients simple sexes. Biofilm formation also investigated using tissue culture plate, it the production biofilm show different potential capacity form biofilm, UTI, is about...
Background: Hepatocellular carcinoma is the third leading cause of tumor related mortality and develops mostly in patients with chronic liver disease cirrhosis. Human hepatocyte growth factor (HGF) produced various organs body characterized as a multifunctional biologic activities. Aim: Our aim was to investigate predictive factors recurrence specially role HGF HCC treated TACE. Patients Methods: one hundred by TACE who achieved complete response were included divided into two groups...
Breast cancer (BC), which is predicted to impact 1.67 million individuals a year, the disease with second highest mortality rate worldwide, most common in women, and ranks fifth among causes of cancer-related death.BC prevalent form Egyptian women.Objective: This review article aimed investigate for updates management triple negative BC (TNBC).Methods: We searched PubMed, Google Scholar, Science Direct relevant articles on: Trible breast cancer, management.Only recent or thorough studies...
Objective: To share our experience in bladder preservation Upper Egypt, Assiut and Sohag Universities, using different treatment protocols.In study patients with operable muscle invasive cancer were included underwent transurethral resection followed by radiochemotherapy (5-fluorouracil Cisplatin) for preservation.In after maximum safe of tumor, received combined chemo-radiotherapy, 60 Gy fractionated radiotherapy over 6 weeks, Cisplatin Gemcitabine.Results: In the age ranged from 35-72ys...
Basal cell carcinoma (BCC) is the most prevalent malignant periocular tumor throughout world, with a higher incidence in age group above 60.Excessive exposure to Ultraviolet radiation one of well-known risk factors.Periocular BCCs more frequently occur on lower lid and medial canthus.If periorbital invasion occurs, orbital exenteration essential.In this report, we present case 72-year-old man recurrent neglected BCC canthus right eye infiltration rectus muscle orbit ethmoid air sinus,...
e12593 Background: For patients with breast cancer, axillary dissection was a standard treatment, especially patient positive metastases in the sentinel nodes. some might be over-treatment, including those who have had mastectomy. Especially new trend of many radiation-therapy centers, provide for any number lymph The aim our work is to evaluate impact dissected nodes (LN), on overall survival (OS) and progression free (PFS) cancer patients. Methods: This retrospective study done Sohag...
Aim of the work:investigate pattern breast cancer recurrence and affecting factors on early late identify site specific recurrence.Patients methods:A retrospective study 141 patients presented to clinical oncology department ,sohag university hospital between January 2000 December 2014 diagnosed with invasive cancer.All them underwent surgery either modified radical mastectomy,simple mastectomy or conservative then received adjuvant systemic therapyeitherchemotherapy,endocrine therapy...