A5084045344- COVID-19 Clinical Research Studies
- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Galectins and Cancer Biology
- COVID-19 Impact on Reproduction
- Antibiotic Resistance in Bacteria
- COVID-19 diagnosis using AI
- Sperm and Testicular Function
- Atherosclerosis and Cardiovascular Diseases
- Biosensors and Analytical Detection
- MicroRNA in disease regulation
- Whipple's Disease and Interleukins
- Ovarian function and disorders
- Vitamin C and Antioxidants Research
- Diagnosis and treatment of tuberculosis
- Immune responses and vaccinations
- Streptococcal Infections and Treatments
- Gut microbiota and health
- Psoriasis: Treatment and Pathogenesis
- Intramuscular injections and effects
- COVID-19 and healthcare impacts
- Gastrointestinal disorders and treatments
- Appendicitis Diagnosis and Management
- Enterobacteriaceae and Cronobacter Research
- Dermatological and COVID-19 studies
Assiut University
2014-2024
Background: The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in a worldwide devastating effect with diagnostic challenge. Identifying risk factors of severity aids assessment for the need early hospitalization. We aimed to demonstrate, first time, clinical, laboratory and radiological characteristics disease 2019 (COVID-19) patients, identify predictors describe antimicrobial resistance profile patients from Upper Egypt. Materials Methods: Demographic...
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Acinetobacter baumannii is a Gram-negative coccobacillus responsible for severe hospital-acquired infections, particularly in intensive care units (ICUs). The current study was designed to characterize the virulence traits of biofilm-forming carbapenem-resistant A. causing pneumonia ICU patients using Galleria mellonella model. Two hundred and thirty with or ventilator-associated were included our study. Among total isolates, most frequently isolated etiological agent (54/165, 32.7%). All...
Lung Cancer (LC) is a major cancer killer worldwide, and 5-yr survival extremely poor (≤15%), accentuating the need for more effective diagnostic therapeutic strategies. Studies have shown cell-free microRNAs (miRNAs) circulating in serum plasma with specific expression cancer, indicating potential of using miRNAs as biomarkers diagnosis therapy. This study aimed to identify differentially-expressed two Non-Small Cell (NSCLC) patients that might be clinically useful tool lung early...
Oxidized low-density lipoprotein (ox-LDL) has an important role in the genesis of coronary atherosclerosis. Lectin-like ox-LDL receptor 1 (OLR1) contributes to uptake and internalization ox-LDL. Genetic polymorphisms have been associated with artery disease (CAD). Here we explore association plasma levels 3' UTR OLR1 (rs1050286) SNP CAD risk in-hospital adverse outcomes.A case-control study enrolled 192 patients ST-segment elevation myocardial infarction (STEMI), 100 unstable angina, healthy...
This study aimed to assess glutathione-S-transferase (GST) enzyme- oxidative stress (OS) relationship in the internal spermatic vein (ISV) of infertile men associated with varicocele (Vx). Ninety five oligoasthenoteratozoospemic (OAT) Vx were subjected history taking, clinical examination and semen analysis. During inguinal varicocelectomy, GST, malondialdehyde (MDA) glutathione peroxidase (GPx) estimated blood samples drawn from ISV median cubital veins. The mean levels GPx significantly...
This work aimed to assess the impact of different etiologies acute pancreatitis (AP) and vitamin D receptor (VDR) TaqI rs731236 gene polymorphism on severity AP.This case-control study included 70 patients with AP 40 healthy controls. Etiologies were identified by imaging, ANA, cytomegalovirus (CMV) IgM, coxsackie B virus IgG4. Genotyping VDR polymorphism, Laboratory tests scores using Ranson, BISAP, Atlanta APACHE II determined.The age in was 36.03 ± 10.76, females 85.7%. The as follows:...
Lower respiratory tract infections can result from a variety of pathogens. The expeditious and precise identification these microorganisms is crucial for determining the most suitable antimicrobial regimen. This study tried to identify microbiological causes hospital-acquired ventilator-associated pneumonia by syndromic multiplex PCR "BioFire FilmArray Pneumonia plus Panel (FA-PP)" correlate results with findings obtained routine culture methods. was conducted on 72 bronchoalveolar lavage...
Covid-19 (COVID-19) is a pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which began in Wuhan, China, and spread globally last few months. COVID-19 affects anticoagulation, most patients who need regular anticoagulant care, not just those infected with (SARS-CoV-2). In COVID-19, coagulopathy causes morbidity mortality. Yet mechanisms are uncertain there biomarkers. Venous thromboembolism, possible reason for unexplained mortality, has often been...
Abstract Background The ability to forecast the progression and severity of coronavirus disease 2019 (COVID-19) is critical for effective management. Objective To determine whether hematological parameters can predict severe COVID-19 at time hospital admission. Patients methods study was conducted on 298 admitted patients. They were categorized into or nonsevere groups. Blood picture done with analysis red-cell distribution width (RDW), neutrophil–lymphocyte ratio (NLR), RDW-to-platelet...
Background: Neonatal sepsis is one of the important causes morbidity and mortality in a neonate.Pantoea species (Pantoea spp) has attracted considerable attention as an emerging neonatal pathogen been associated with life-threatening septic arthritis, occupational respiratory infections, bloodstream infections neonates infants globally.Methods: We aimed to determine prevalence Pantoea spp from cases, sources its infection.Pantoea isolates were isolated identificatied by conventional methods...
Abstract Background: Alterations of intestinal microbiota may play a role in the pathogenesis psoriasis. Dysbiosis cause disruption barrier, which contributes to immune activation by translocation microbial antigens and metabolites. Intestinal fatty acid-binding protein (I-FABP) serves as biomarker enterocyte damage. Purpose: The aim this study was investigate serum concentration I-FABP patients with Methods: A cross-sectional hospital-based on fifty psoriatic thirty-five age sex-matched...
Background: A number of factors have been proposed to be predictive benefit for males with a good probability retrieve sperms; as testicular volume, serum FSH, total testosterone and Inhibin B levels.However, little information has present regarding the use seminal Clusterin (CLU) that purpose.Aim: We designed study in order estimate CLU level non-obstructive azoospermia (NOA) undergoing Testicular sperm extraction (TESE), also detect possibility its predictor spermatogenesis those...
Background Tuberculosis (TB) management and prevention of further spread is crucially based on early prompt diagnosis. Even though conventional methods are the gold standard for detection Mycobacterium tuberculosis (MTB), they time consuming do not detect nontuberculous mycobacteria in most cases. The present study evaluated Anyplex MTB/NTM real-time (RT)-PCR assay (Seegene) TB diagnosis pulmonary extrapulmonary cases comparison with culture Lowenstein–Jensen as a MTB. Patients included 100...