Quantum dot (QD) nanocrystals which have important optical properties, in particular, the wavelength of their fluorescence, depend strongly on size. Colloidal QDs once dispersed a solvent are quite interesting fluorescence probes for all types labelling studies because reduced tendency to photo bleach. In this review, we will give an overview how been used so far cell biology. discuss biologically relevant properties and focus four topics: labeling cellular structures receptors with QDs,...

The occurrence of large landslides in sensitive clays, such as spreads, can be modelled by progressive development inelastic shear deformation zones (shear bands). main objective the present study is to perform finite-element modelling clay slopes simulate failure and dislocation failed soil mass using coupled Eulerian Lagrangian (CEL) approach available Abaqus software. degradation undrained strength with plastic strain (strain-softening) implemented CEL, which then used initiation...

Biofilm-mediated wound infections pose a significant challenge due to the limitations of conventional antibiotics, which often exhibit narrow-spectrum activity, fail eliminate recurrent bacterial contamination, and are unable penetrate biofilm matrix. While search for alternatives has explored use metal nanoparticles synthetic biocides, these solutions suffer from unintended toxicity surrounding tissues lack controlled administration release. In this study, we engineered pH-responsive...

A large-deformation finite-element (FE) modelling technique is presented to model submarine landslides. strain softening for undrained shear strength of marine clay incorporated in the FE modelling. The development large plastic concentrated zones (shear bands) and their propagation with displacement soil mass are simulated. simulations show that existence a weak layer might result initiation bands leading large-scale progressive Such failure planes cannot be simulated using limit...

Post-slide investigations suggest that many large-scale submarine landslides occur through marine sensitive clay layers. A nonlinear mathematical model for post-peak degradation of undrained shear strength is proposed based on experimental results. method estimation parameters presented. Incorporating the model, an analytical solution developed to examine possible mechanisms landslides. Analyses are performed mild infinite slopes where failure initiates from a “fully weakened zone” soil...

Uncontrollable haemorrhage and associated microbial contamination in the battlefield civilian injuries pose a tremendous threat to healthcare professionals. Such traumatic wounds often necessitate an effective point-of-care solution prevent consequent morbidity owing blood loss or haemorrhage. However, developing superior hemostatic materials with anti-infective properties remains challenge. To address this, injectable, cationic dextran-mesoporous silica nanoparticle-based bactericidal...

With the increasing focus on healthcare research in current times, therapeutic and biomaterial interventions for healing of wounds mitigation wound-associated infections have seen expedited progress. Conventional approaches consist release-active gels, which demonstrate leaching antimicrobials, such as antibiotics, metal ions, etc. However, these systems suffer from disadvantages burst release, reservoir exhaustion, associated toxicity. In this report, intrinsically antimicrobial hydrogel...

Gram-negative bacterial infections pose a significant challenge due to two major resistance elements, including the impermeability of outer membrane and overexpression efflux pumps, which contribute antibiotic resistance. Additionally, coexistence multispecies superbugs in mixed species biofilms further complicates treatment, as these are refractory most antibiotics. To address this issue, combining obsolete antibiotics with non-antibiotic adjuvants that target membranes has shown promise...

The rapid growth of antibiotic resistance in Staphylococcus aureus coupled with their biofilm forming ability has made the infections difficult to treat conventional antibiotics. This created a massive threat towards public health and is huge concern worldwide. Aiming address this challenging issue, herein we report new class small antibacterial molecules (SAMs) high activity against multidrug-resistant S. aureus. design principle was based on variation hydrophobic/hydrophilic balance...

Silicon nitride (Si3 N4) nanowires have been prepared by carbothermal reduction followed the nitridation (CTRN) of silica gel containing ultrafine excess carbon obtained decomposition dextrose over temperature range 1200-1350 °C. This innovative process involves repeated evacuation purging nitrogen gas so that interconnected nanopores are filled with prior to heat treatment. During treatment at higher temperatures, presence in starts CTRN reaction simultaneously throughout bulk gel, leading...