Salmonellaenterica serovar Enteritidis and Campylobacter jejuni are 2 major foodborne pathogens transmitted through poultry products. These colonize the chicken cecum, leading to contamination of carcasses during slaughter subsequent processing operations. We investigated antimicrobial efficacy 4 GRAS (generally recognized as safe) status plant-derived molecules, namely, trans-cinnamaldehyde, eugenol, carvacrol, thymol, against Salmonella C. in cecal contents vitro. The plant molecules were...

ABSTRACT The efficacies of trans -cinnamaldehyde (TC) and eugenol (EG) for reducing Salmonella enterica serovar Enteritidis colonization in broiler chickens were investigated. In three experiments each compound, 1-day-old chicks ( n = 75/experiment) randomly assigned to five treatment groups 15/treatment group): negative control (-ve S . Enteritidis, -ve TC, or EG), compound +ve 0.75% [vol/wt] TC 1% positive (+ve low-dose 0.5% high-dose EG). On day 0, birds tested the presence any inherent...

Acinetobacter baumannii is a multidrug resistant pathogen capable of causing wide spectrum clinical conditions in humans. spp. ubiquitously found different water sources. Chlorine being the most commonly used disinfectant water, study investigated effect chlorine on survival A. and transcription genes conferring antibiotic resistance. Eight isolates baumannii, including fatal meningitis isolate (ATCC 17978) (~108 CFU/mL) were separately exposed to free concentrations (0.2, 1, 2, 3 4 ppm)...

Clostridium difficile is a nosocomial pathogen that causes serious toxin-mediated enteric disease in humans. Reducing C. toxin production could significantly minimize its pathogenicity and improve outcomes This study investigated the efficacy of two, food-grade, plant-derived compounds, namely trans-cinnamaldehyde (TC) carvacrol (CR) reducing cytotoxicity vitro. Three hypervirulent isolates were grown with or without sub-inhibitory concentrations TC CR, culture supernatant bacterial pellet...

This study investigated the efficacy of plant-derived antimicrobials, namely, trans-cinnamaldehyde, β-resorcylic acid, carvacrol, thymol, and eugenol or their combination, in increasing sensitivity Salmonella Typhimurium DT104 to five antibiotics. The subinhibitory concentrations each antimicrobial combination containing lower than individual were added tryptic soy broth supplemented with antibiotics at respective break points for resistance. was inoculated into ∼6 log CFU/mL, growth...

Abstract C ampylobacter is a leading worldwide cause of foodborne illness associated with consumption poultry products. Unfortunately, most preharvest treatments fail to reduce this enteric pathogen in poultry. The efficacy natural plant extracts, such as thymol and carvacrol, has against other pathogens but not been evaluated . To accomplish this, day old broiler chicks ( n = 10 chicks/dose) were fed 0% (controls) or carvacrol combinations these compounds feed four different trials. Birds...

Salmonella Enteritidis (SE) is a major foodborne pathogen in the United States and one of most frequently reported serotypes globally. Eggs are common food product associated with SE infections humans. The colonizes intestinal tract layers, migrates to reproductive organs systemically. Since adhesion invasion chicken oviduct epithelial cells (COEC) critical for colonization tract, reducing these virulence factors could potentially decrease egg yolk contamination. This study investigated...

To date, the selection of candidate strains for probiotic development in production animals has been largely based upon screens desired phenotypic traits. However, increasing evidence indicates that use host-specific may be important, because coevolution with animal host better prepares a bacterial strain to colonize and succeed its respective species. This concept was applied Lactobacillus johnsonii commercial poultry previous correlation enhanced bird performance. Using 204 naturally...

Salmonella enterica serovar Enteritidis is a major foodborne pathogen in the United States, causing gastroenteritis humans, primarily through consumption of contaminated eggs. Chickens are reservoir host S. Enteritidis. In layer hens, colonizes intestine and migrates to various organs, including oviduct, leading egg contamination. This study investigated efficacy in-feed supplementation with trans-cinnamaldehyde (TC), generally recognized as safe (GRAS) plant compound obtained from cinnamon,...

Salmonella Enteritidis is a common foodborne pathogen transmitted to humans largely by consumption of contaminated eggs. The external surface eggs becomes with from various sources on farms, the main being hens' droppings and litter. Therefore, effective egg disinfection critical reduce pathogens potentially control egg-borne disease outbreaks. This study investigated efficacy GRAS (generally recognized as safe) status, plant-derived antimicrobials (PDA), namely trans-cinnamaldehyde (TC),...

Aflatoxins (AF) are toxic metabolites primarily produced by molds, Aspergillus flavus and parasiticus. Contamination of poultry feed with AF is a major concern to the industry due severe economic losses stemming from poor performance, reduced egg production, diminished hatchability. This study investigated inhibitory effect 2 generally regarded as safe (GRAS), natural plant compounds, namely carvacrol (CR) trans-cinnamaldehyde (TC), on A. parasiticus growth production in potato dextrose...

Multi-drug resistant (MDR) Acinetobacter baumannii is a major nosocomial pathogen causing wide range of clinical conditions with significant mortality rates. A. strains are equipped multitude antibiotic resistance mechanisms, rendering them to most the currently available antibiotics. Thus, there critical need explore novel strategies for controlling in baumannii. This study investigated efficacy two food-grade, plant-derived antimicrobials (PDAs), namely trans-cinnamaldehyde (TC) and...

We investigated the efficacy of feed supplemented with caprylic acid (CA), a natural, 8-carbon fatty for reducing Salmonellaenterica serovar Enteritidis colonization in commercial broiler chickens. In separate 3- and 6-wk trials, 1-d-old straight-run chicks (n = 70 birds/trial) were assigned to control group (challenged Salmonella Enteritidis, no CA) 2 replicates 0.7 1% CA 14 birds/group). Water provided ad libitum. On d 1, birds tested any inherent For 3-wk trial, on 5, challenged 8 log10...

Salmonella Heidelberg (S. Heidelberg) is a major pathogen implicated in foodborne outbreaks for which poultry products can serve as an epidemiological source. This study determined the efficacy of GRAS-status lemongrass essential oil (LGEO) against S. vitro and on pathogen's attachment to skin meat. At first, employing assays, effect LGEO multidrug-resistant multiplication motility was examined. Biofilm inhibition inactivation assays were also performed. The quorum-sensing modulating...

Salmonella Enteritidis and Campylobacter jejuni are 2 major foodborne pathogens in the United States, estimated to cause more than 3 million cases of human illness annually. Chickens natural hosts these bacteria, their drinking water can be a source S. C. jejuni, contributing colonization birds. In this study, trans-cinnamaldehyde (TC), natural, generally recognized as safe ingredient cinnamon oil was evaluated for its efficacy inactivate chickens. Well containing 0, 0.016, 0.03, 0.06% TC...

In this study, we investigated the therapeutic efficacy of plant compounds trans-cinnamaldehyde (TC) and eugenol (EG) on reducing Salmonella enterica serovar Enteritidis (SE) in commercial, market-age broiler chickens. Straight run, day-old commercial chicks (N = 84) were randomly grouped into 6 groups 14 birds each (n 14/group): a negative control (no SE, no TC or EG), EG 1% 0.75% TC), positive (SE, an challenge group TC). Before start experiment, flock was screened for any inherent 12...