A5052373467- Global Cancer Incidence and Screening
- Cancer Risks and Factors
- COVID-19 Clinical Research Studies
- Cervical Cancer and HPV Research
- Breast Lesions and Carcinomas
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Wound Healing and Treatments
- Cancer Cells and Metastasis
- Anesthesia and Neurotoxicity Research
- CNS Lymphoma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Cancer and Skin Lesions
- Neurological Complications and Syndromes
- Advanced Breast Cancer Therapies
- Immune Cell Function and Interaction
- Nonmelanoma Skin Cancer Studies
- Biomedical and Chemical Research
- Healthcare Systems and Public Health
- Lymphoma Diagnosis and Treatment
- Ethics in Clinical Research
- Bladder and Urothelial Cancer Treatments
- Environmental Monitoring and Data Management
- Immunotherapy and Immune Responses
- Vascular Tumors and Angiosarcomas
Gomel State Medical University
2020-2025
State Healthcare Institution "Regional Clinical Oncological Dispensary"
2021-2023
Relevance . The development and production of own vaccine contributes to the growth professional competencies scientific community, improvement modernization country's industrial production. Aims To evaluate immunogenicity parameters whole-virion against SARS-CoV-2 in a phase I, II clinical trial (up day 180). Materials & Methods study included I/II trial. In Phase sequential allocation subjects (1:1) by open-label method into two groups with single administration at dose 1 2 was...
This article presents a clinical case of primary cerebral lymphoma diagnosed in an HIV-infected patient. Clinical manifestations the presented pathology, and methods for its diagnostic were described. is scientific interest to doctors various specialities, as brain lesions immunocompromised patients may manifest with wide range diseases different etiologies, variety pathomorphological features, moreover most pathological conditions do not have pathognomonic symptoms variable symptoms.
New treatment options for metastasised high-grade serous carcinoma (HGSC) are urgently needed. HGSC frequently metastasises to the omentum, inducing angiogenesis in local omental microvasculature facilitate tumour growth. We previously showed that HGSC-secreted cathepsin L (CathL) induces pro-angiogenic changes disease relevant human microvascular endothelial cells (HOMECs), suggesting a role angiogenesis. Here we investigate whether CathL acts by production of carbohydrate-binding protein...
Relevance. According to the World Health Organization (WHO), it is not yet possible effectively stop spread of new strains coronavirus [1]. At same time, most experts and analysts in field medicine publicly admit that at moment vaccination powerful weapon fight against COVID-19 [2–6]. While vaccination, like entire health care system, has now become an element politics economics, creation proprietary vaccine each country national security [7]. Aims. To evaluate safety inactivated booster...
Objective. To analyze locoregional relapses (LRR) after reconstructive plastic and organ-preserving operations in breast cancer (BC)Materials methods. A retrospective analysis of the results treatment 303 patients with BC who underwent period from 2014 to 2019 Oncological Department General Oncology Rehabilitation Gomel Regional Clinical Dispensary was carried out. The median age 44 years (25-70 years). Statistical data processing out using application software package “Statistica”, 10.0....
Objective. To analyze the time series of morbidity and mortality from breast cancer, prostate colorectal cancer cervical in Gomel region for period 1982 to 2022 using ARIMA method make a prediction up 2030. Materials methods. We analyzed data these cancers statistical methods, including modeling. Data on age at diagnosis, stage disease, percentages detected different stages, its dynamics after diagnosis were used. Results. On basis analysis model, model predicting incidence near future was...
Objective . To make a comprehensive evaluation of the epidemiological situation on incidence rate breast cancer (BC) in Gomel region, to analyze dynamics morbidity and mortality, as well study degree disability result this disease. Materials methods The data morbidity, mortality primary from BC region for 2013-2023 were analyzed. Results stands out among other cancers terms – 111.8 per 100,000 population, which is significantly higher than 2023. Thus, more twice high uterine body (43.6) even...
The article analyzes the use of polymer materials for solving problems theoretical and practical medicine. effectiveness polymers in reconstructive cardiac surgery, radiation therapy, etc. has been shown. basic requirements set composites medical devices have identified. most important criterion selection is safety their clinical practice ability to biodegrade when they enter a living organism along usual metabolic pathways absence inflammatory allergic reactions surrounding tissues during...
Objective. Conduct a comprehensive assessment of the indicators screening programs for early detection breast and cervical cancer in Gomel region. Materials methods. A total 7,611 first-time detected cases 1,370 region were analyzed period 2012-2022 (according to Belarusian Cancer Registry). The results examination 105130 participants program 70258 analyzed. Results. During 2017-2022, due screening, 12% from number newly diagnosed malignant pathologies. From 2018 2022, proportion within...
Breast cancer is the most common malignancy in female population. Early detection of breast crucial for reducing mortality from disease. Late may have an unfavorable prognosis. Study Objective – To evaluate awareness population Gomel region concerning prevention and early diagnostics cancer. The participants were 317 women, all them full age, gave their consent to participate present study, filled a specially designed questionnaire. Absolute majority respondents know that effectiveness...
Цель. Провести сравнительный анализ затрат финансовых средств, требуемых для реализации использованных в работе методов жидкостной и традиционной цитологии клеточного осадка мочи, обоснования экономической эффективности целесообразности внедрения метода работу цитологических лабораторий. Материалы методы. Цитологические препараты мочи были приготовлены с использованием (ТЦ) (ЖЦ). Было проанализировано 826 карт амбулаторного наблюдения пациентов установленным диагнозом уротелиальной карциномы...
Цель. Провести сравнительный анализ способов стандартизации преаналитического лабораторного этапа цитологического исследования клеточного осадка мочи с расчетом экономической эффективности применяемых методов. Материалы и методы. Цитологические препараты были приготовлены использованием методов жидкостной цитологии (ЖЦ), цитоцентрифугирования (ЦЦ) простого центрифугирования (традиционного (ТЦ)). Было проанализировано 1930 образцов пациентов установленным диагнозом уротелиальной карциномы...
Background . In 1–2 % of cases, burn scars can cause more aggressive skin cancer that has a worse prognosis than conventional cancer. Most scar carcinomas are the squamous cell type (88 %) with frequency metastasis 27 %. Due to rarity this malignancy and absence guidance, treatment carcinoma continues be controversial. Surgical excision remains standard mode for skin. Surgery is associated problems define required limit achieve clear margins; subsequent grafting postoperative defect limited...
Objective. To study the effectiveness of liquid cytological diagnosis bladder cancer and its local relapses using Cellprep Plus technology as an example. Materials methods. We analyzed outpatient records patients with urothelial pathology (n = 806) who underwent a urine cytology exam by methods 383) conventional 423) cytology. Results. The diagnostic sensitivity specificity examination method for diagnosing carcinoma have been found to be 93.4 % 95.4 respectively, which significantly exceeds...