Hailan Wang

ORCID: 0000-0002-4740-4606
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About
Contact & Profiles
Research Areas
  • Luminescence and Fluorescent Materials
  • RNA modifications and cancer
  • Autophagy in Disease and Therapy
  • Molecular Sensors and Ion Detection
  • Nanoplatforms for cancer theranostics
  • Network Security and Intrusion Detection
  • Carcinogens and Genotoxicity Assessment
  • Advanced Text Analysis Techniques
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • MicroRNA in disease regulation
  • Tree-ring climate responses
  • Organic Light-Emitting Diodes Research
  • Membrane Separation Technologies
  • Inflammasome and immune disorders
  • Advanced Algorithms and Applications
  • Photochromic and Fluorescence Chemistry
  • Plant Water Relations and Carbon Dynamics
  • Face and Expression Recognition
  • Cancer-related molecular mechanisms research
  • Web Data Mining and Analysis
  • Adipose Tissue and Metabolism
  • Software System Performance and Reliability
  • Polydiacetylene-based materials and applications
  • Solar-Powered Water Purification Methods

Southern Medical University
2022-2025

Nanjing Medical University
2023-2025

Guilin University of Technology
2022-2024

Northwestern Polytechnical University
2021-2024

Henan Provincial People's Hospital
2024

Henan University
2024

Shandong University
2019-2024

Xihua University
2023-2024

Zhengzhou University
2024

Affiliated Hospital of Southwest Medical University
2021-2024

Abstract Photochromic materials have drawn enormous attention for their potential applications in optical memory storage and photoswitchable molecular devices. Although great achievements photochromic been fulfilled, it is still a big challenge to realize gated photochromism ready tunable properties. In previous studies, rare examples of are reported. Herein, three triarylethylene derivatives FTrPE‐ o I, ClTrPE‐ I BrTrPE‐ with reversible thermally activated characteristics designed...

10.1002/adfm.202312930 article EN Advanced Functional Materials 2024-02-21

Abstract Self-monitoring materials have promising applications in structural health monitoring. However, developing organic afterglow for self-monitoring is a highly intriguing yet challenging task. Herein, we design two molecules with twisted donor-acceptor-acceptor’ configuration and achieve dual-emissive tunable lifetimes (86.1–287.7 ms) by doping into various matrices. Based on photosensitive resin, series of complex structures are prepared using 3D printing technology. They exhibit...

10.1038/s41467-024-45497-4 article EN cc-by Nature Communications 2024-02-21

A forest fire is a natural disaster that destroys resources, thus having severe impact on humans and the animals plants depend environment. This paper presents model for predicting scale of wildfires Alberta, Canada. fire's determined by combination duration size area it burns. Our prediction enables rescuers to take appropriate measures minimize damage caused wildfire based its predicted in early stages. The modeling data were collected from Canada National Fire Database (CNFDB) published...

10.1109/access.2019.2957837 article EN cc-by IEEE Access 2019-01-01

Abstract With the increasing demands of X‐ray detection and medical diagnosis, organic scintillators with intense tunable excited emission have been becoming important. To guarantee absorption, heavy atoms were widely added in reported scintillators, which led to quenching. In this work, we propose a new strategy realize through host‐guest doping strategy. Then absorption centers (host) (guest) are separated. Under excitation, these materials displayed readily emissions ranging from green...

10.1002/anie.202316190 article EN Angewandte Chemie International Edition 2023-11-28

Photochromic polymer is defined as a series of materials based on photochromic units in chains, which produces reversible color changes under irradiation with particular wavelength. Currently, the research progresses, it shows increasing potential applications various fields, such anti-counterfeiting, information storage, super-resolution imaging, and logic gates. However, there paucity published reviews topic polymers. Herein, this review discusses summarizes progress prospects materials,...

10.34133/research.0392 article EN cc-by Research 2024-01-01

1-Bromopropane has been newly introduced as an alternative to ozone-depleting solvents. We aimed clarify its dose-dependent reproductive toxicity in male rats. Thirty-six Wistar rats were randomly divided into 4 groups of 9. The exposed 200, 400, or 800 ppm 1-bromopropane only fresh air, 8 h per day for 12 weeks. Epididymal sperm indices evaluated after a 12-week exposure. testes, epididymides, seminal vesicle, prostate, and other organs weighed examined histopathologically. Spermatogenic...

10.1093/toxsci/54.2.416 article EN Toxicological Sciences 2000-04-01

N-methyl-D-aspartate receptor antagonists and nonsteroidal anti-inflammatory drugs are believed to prevent opioid-induced hyperalgesia and/or acute opioid tolerance, which could cause an increase in postoperative requirement. In this randomized, double-blind, placebo-controlled study, we investigated whether co-administration of ketamine or lornoxicam fentanyl the morphine requirement induced by alone.Ninety females undergoing total abdominal hysterectomy with spinal anesthesia were randomly...

10.1213/ane.0b013e3181888061 article EN Anesthesia & Analgesia 2008-11-13

Cigarettes contain various chemicals that cause damage to nerve cells. Exposure cigarette smoke (CS) causes insulin resistance (IR) in However, the mechanisms for a disorder cigarette-induced signaling pathway and neurotoxicity remain unclear. Therefore, we evaluated, by series of pathology analyses behavioral tests, neurotoxic effects chronic exposure CS on C57BL/6 mice. Mice exposed with more than 200 mg/m3 total particulate matter (TPM) exhibited memory deficits cognitive impairment....

10.3390/toxics11120969 article EN cc-by Toxics 2023-11-30

The increased drug resistance and metastasis of melanoma resulted in poor prognosis patients. Here, we designed synthesized a novel hemicyanine-based fluorescent probe ZWZ-3, investigated its application for imaging treatment both vitro vivo. ZWZ-3 preferentially accumulated cells via process that depended on the organic anion-transporting polypeptide (OATP), which targeted mitochondria hemicyanine cationic nitrogen. In addition, effect molecular mechanism melanoma. studies showed promoted...

10.3389/fphar.2022.829684 article EN cc-by Frontiers in Pharmacology 2022-02-23

Quinoxaline 1, 4-dioxides (QdNOs) has been used in animals as antimicrobial agents and growth promoters for decades. However, the resistance to QdNOs pathogenic bacteria raises worldwide concern but it is barely known. To explore molecular mechanism involved development of Escherichia coli, 6 strains selected by vitro 21 isolated from QdNOs-used swine farm were subjected MIC determination PCR amplification oqxA gene. A conjugative transfer was carried out evaluate risk resistant determinant....

10.1371/journal.pone.0043322 article EN cc-by PLoS ONE 2012-08-28

Popular topic detection is a identification by the information of documents posted users in social networking platforms. In large body research literature, most popular methods identify distribution unknown topics integrating from based on However, among these methods, them have low accuracy due to short text content and abundance useless punctuation marks emoticons. Image texts has also been overlooked, while this may contain real matter user's content. order solve above problems improve...

10.1016/j.websem.2024.100820 article EN cc-by Journal of Web Semantics 2024-05-08

An intricate network of cis - and trans -elements acts on RNA N 6 -methyladenosine (m A), which in turn may affect gene expression and, ultimately, human health. A complete understanding this requires new approaches to accurately measure the subtle m differences arising from genetic variants, many have been associated with common diseases. To address gap, we developed a method sensitively detect transcriptome-wide allele-specific (ASm A) MeRIP-seq data applied it uncover 12,056...

10.1101/gr.277704.123 article EN Genome Research 2023-08-01
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