Han Yan

ORCID: 0000-0002-4754-3390
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About
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Research Areas
  • COVID-19 epidemiological studies
  • COVID-19 Pandemic Impacts
  • Advanced Neuroimaging Techniques and Applications
  • Influenza Virus Research Studies
  • Traditional Chinese Medicine Studies
  • Circular RNAs in diseases
  • Cancer Mechanisms and Therapy
  • Computational Drug Discovery Methods
  • Corporate Finance and Governance
  • Colorectal Cancer Treatments and Studies
  • Hematopoietic Stem Cell Transplantation
  • Global Public Health Policies and Epidemiology
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • MicroRNA in disease regulation
  • Cholinesterase and Neurodegenerative Diseases
  • Agricultural risk and resilience
  • Radiomics and Machine Learning in Medical Imaging
  • International Business and FDI
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Income, Poverty, and Inequality
  • Poisoning and overdose treatments
  • Risk Management in Financial Firms
  • Acute Myeloid Leukemia Research
  • Functional Brain Connectivity Studies
  • Bone health and osteoporosis research

Yueyang Hospital
2023

Shanghai University of Traditional Chinese Medicine
2023

Union Hospital
2020-2023

Huazhong University of Science and Technology
2017-2023

Sir Run Run Shaw Hospital
2022

Zhejiang University
2022

Southern Medical University
2021

Peking University
2020-2021

Fudan University
2021

Sichuan University
2020

Abstract By proposing a varying coefficient Susceptible-Infected-Removal model (vSIR), we track the epidemic of COVID-19 in 30 provinces China and 15 cities Hubei province, epicenter outbreak. It is found that spread has been significantly slowing down within two weeks from January 27 to February 10th with 87.0% 84.3% reductions reproduction number R 0 among cities, respectively. This suggests extreme control measures implemented since 23, which include cutting off Wuhan many other towns,...

10.1101/2020.02.17.20024257 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-02-20

Abstract This study aimed to explore the changes in functional connections between cerebral hemispheres and local brain regions activities patients with acute ischemic stroke (AIS) treated International Standard Scalp Acupuncture (ISSA). Thirty middle artery AIS dominant hemisphere were selected randomly divided into two groups such as control group scalp acupuncture group, 15 each group. Patients conventional Western medicine, while received ISSA (acupuncture at parietal midline [MS5], left...

10.1002/ar.24746 article EN cc-by-nc The Anatomical Record 2021-08-25

Objective: To estimate the health impact and economic burden of seasonal influenza in mainland China. Methods: From systematic literature reviews, we collected influenza-associated excess influenza-like-illness (ILI) outpatient consultation rates, hospitalization rates severe acute respiratory infections (SARI) mortality, 2006-2017. Using these data, as well demographic data (2019), number ILI consultations, SARI hospitalizations deaths were estimated. Then using per capita consultations...

10.3760/cma.j.cn112137-20201210-03323 article EN Zhonghua yixue zazhi 2021-03-01

Abstract MALAT1 is one of the most hopeful members implicated in angiogenesis a variety non-malignant diseases. In multiple myeloma (MM), recognized as highly expressed long non-coding RNA. However, functional roles and responsible mechanisms have not yet been explored. Herein, we discovered novel regulatory network dependent on relation to MM tumorigenesis angiogenesis. We observed that was upregulated significantly associated with poor overall survival. knockdown suppressed cell...

10.1093/carcin/bgad053 article EN Carcinogenesis 2023-08-07

We study epidemiological characteristics of 25 early COVID-19 outbreak countries, which emphasizes on the reproduction infection and effects government control measures. The is based a vSIADR model allows asymptomatic pre-diagnosis infections to reflect clinical realities, linear mixed-effect analyse association between each country's measures effective number Rt . It finds significant higher stringency in lowering reproduction, shortening effect time epidemic turning point by applying...

10.1098/rspa.2020.0440 article EN cc-by Proceedings of the Royal Society A Mathematical Physical and Engineering Sciences 2021-04-01

Gait disturbance is a manifestation of cerebral small vessel disease (CSVD). The posterolateral thalamus (PL), whose blood mainly supplied by the P2 segment posterior artery (P2-PCA), plays pivotal roles in gait regulation. We investigated influence distance between P2-PCA and PL on with varying CSVD burden. 71 participants were divided into low high burden groups. from to was measured using 7 T TOF-MRA categorized an immediate or distant PCA-to-thalamus pattern. Functional connectivity (FC)...

10.1016/j.nbd.2023.106372 article EN cc-by-nc-nd Neurobiology of Disease 2023-12-05

We evaluate the effectiveness of COVID-19 control strategies 25 countries which have endured more than four weeks community infections. With an extended SEIR model that allows infections in both exposed and infected states, key epidemic parameters are estimated from each country’s data, facilitate evaluation cross-country comparison. It is found quicker measures significantly reduce average reproduction numbers shorten time length to infection peaks. If swift Korea China were implemented,...

10.1101/2020.04.27.20081232 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-05-03

Objective: To compare the clinical efficacy of different doses rabbit antithymocyte globulin (rATG) in haplo-HSCT treatment hematologic malignancies. Methods: Malignant hematological patients treated at our hospital from March 2013 to December 2018 were retrospectively analyzed. These divided into three groups as per ATG (6 mg/kg, 7.5 and 9 mg/kg) conditioning regimens. The transplant outcomes compared terms occurrence acute graft versus host disease (GVHD) , infection, survival. Results:...

10.3760/cma.j.issn.0253-2727.2020.07.005 article EN PubMed 2020-07-14

<h3>Objective</h3> To evaluate the efficacy and safety for treatment of coronary heart disease with cobalt-base alloy bio absorbable polymer sirolimus-eluting stent. <h3>Methods</h3> A total 228 patients up to two de novo native artery lesions (reference vessel diameter, 2.5 4.0 mm; target lesion stenosis ≥70%; length ≤40 mm) were randomised 1:1 stent (CAS) group (n=105) versus PARTNER (n=123). Antiplatelet therapy consisted aspirin (100 mg/d) clopidogrel (75 ≥12 months. Clinical follow-up...

10.1136/heartjnl-2011-300867.435 article EN Heart 2011-10-01

There remains a persistent unmet need to detect the disease nonresponse (nonDR) subgroup before adjuvant therapy in synchronous liver metastasis patients with colorectal cancer. Ma's radiomics-clinical nomogram shows potential for early detection of nonDR subgroups, but it is not good enough owing at least three limitaions, which we address this letter editor. First, study did explore RAS/BRAF mutations, HER2 amplifications, etc. complement current nomogram. Second, was validated left- and...

10.3748/wjg.v28.i9.973 article EN cc-by-nc World Journal of Gastroenterology 2022-03-03

Objective: To investigate the prevalence and related factors of osteoporosis among retired population in Dongfeng-Tongji cohort. Methods: 27 009 participants were recruited from Dongfeng Motor Corporation Hubei Province 2008 followed up April to October 2013. newly also recruited. Data collected by using questionnaire, physical examination, serum hepatase detection bone densitometry. Totally, 30 916 included for data analysis after excluding with severe metabolic diseases, taking hormone...

10.3760/cma.j.issn.0253-9624.2017.10.011 article EN PubMed 2017-10-06
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