A5000099476- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Metal complexes synthesis and properties
- Crystal structures of chemical compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Magnetism in coordination complexes
- Molecular Sensors and Ion Detection
- Synthesis and biological activity
- Click Chemistry and Applications
- Chemical Synthesis and Analysis
- CO2 Reduction Techniques and Catalysts
- Organometallic Complex Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Computational Drug Discovery Methods
- Lanthanide and Transition Metal Complexes
- Polyoxometalates: Synthesis and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Vanadium and Halogenation Chemistry
- Organometallic Compounds Synthesis and Characterization
- Axial and Atropisomeric Chirality Synthesis
- Inorganic Chemistry and Materials
- Radiopharmaceutical Chemistry and Applications
- Oxidative Organic Chemistry Reactions
- Metal-Catalyzed Oxygenation Mechanisms
University of Fribourg
2016-2025
University of Belgrade
2020
School of Engineering and Architecture of Fribourg
2020
HES-SO University of Applied Sciences and Arts Western Switzerland
2020
Financial Research Institute of the Ministry of Finance of the Russian Federation
2017
Fribourg Development Agency
2015-2017
The interactions of four Cu-TSC complexes with DNA & their cytotoxicity studies against the HeLa cell have been reported.
Abstract Multiresponsive materials that display predefined photoluminescence color changes upon exposure to different stimuli are attractive candidates for advanced sensing schemes. Herein, we report a cyano‐substituted oligo( p ‐phenylene vinylene) (cyano‐OPV) derivative forms five solvent‐free solid‐state molecular assemblies, luminescence properties of which change thermal and mechanical stimulation. Single‐crystal X‐ray structural analysis suggested tolyl groups introduced at the termini...
The study of DNA/BSA interaction and the catalytic potential four mononuclear oxidoalkoxido vanadium(v) [VVO(L1-4)OEt] (1-4) one dinuclear mixed-ligand [{VO(L2)OEt}2(Q)]{Q = 4,4'-bipyridine}(5) complexes, with tridentate binegative aroylazine ligands are reported [where H2L1 anthranylhydrazone 2-hydroxy-1-napthaldehyde, H2L2 salicylhydrazone H2L3 benzoylhydrazone 2-hydroxy-1-acetonaphthone, H2L4 2-hydroxy-1-acetonaphthone]. All complexes characterized by elemental analysis as well various...
We have prepared a series of ten 3-arylcoumarin molecules, their respective fac-[Re(CO)3(bpy)L]+ and fac-[Re(CO)3(L⁀L)Br] complexes tested all compounds for antimicrobial efficacy. Whereas the ligands are virtually inactive against human-associated pathogens with minimum inhibitory concentrations (MICs) > 150 μM, when coordinated to fac-[Re(CO)3]+ core, most resulting showed remarkable antibacterial potency. Several rhenium exhibit activity in nanomolar Gram-positive such as Staphylococcus...
In the context of global health issue caused by growing occurrence antimicrobial resistance (AMR), need for novel agents is becoming alarming. Inorganic and organometallic complexes represent a relatively untapped source antibiotics. Here, we report computer-aided drug design (CADD) based on 'scaffold-hopping' approach synthesis antibacterial evaluation fac-Re(I) tricarbonyl bearing clotrimazole (ctz) as monodentate ligand. The prepared molecules were selected following pre-screening in...
Four novel dimeric bis-μ-imido bridged metal–metal bonded oxidomolybdenum(V) complexes [MoV2O2L′21–4] (1–4) (where L′1–4 are rearranged ligands formed in situ from H2L1–4) and a new mononuclear dioxidomolybdenum(VI) complex [MoVIO2L5] (5) synthesized salen type N2O2 reported. This rare series of imido-bridged have been furnished H3L′1–4 ligands, containing an aromatic diimine (o-phenylenediamine) "linker", where Mo assisted hydrolysis followed by −C═N bond cleavage one the arms ligand H2L1–4...
Indium is a nonphysiological toxic metal widely used in industry. While misunderstood, its toxicity proposed to be linked perturbation of Fe3+ homeostasis through the binding In3+ ions essential iron metalloproteins such as transferrins. Therefore, monitoring and biological environments prime interest for both basic research diagnosis. Here we report design salen-type anthracene-based probe able selectively sense discriminate Fe2+/3+ by fluoro-colorimetry.
The recovery and separation of organic solvents is highly important for the chemical industry environmental protection. In this context, porous polymers (POPs) have significant potential owing to possibility integrating shape‐persistent macrocyclic units with high guest selectivity. Here, we report synthesis a polymer (np‐POP) corresponding model compound by reacting cyclotetrabenzil naphthalene octaketone macrocycle 1,2,4,5‐tetraaminobenzene 1,2‐diaminobenzene, respectively, under...
The recovery and separation of organic solvents is highly important for the chemical industry environmental protection. In this context, porous polymers (POPs) have significant potential owing to possibility integrating shape‐persistent macrocyclic units with high guest selectivity. Here, we report synthesis a polymer (np‐POP) corresponding model compound by reacting cyclotetrabenzil naphthalene octaketone macrocycle 1,2,4,5‐tetraaminobenzene 1,2‐diaminobenzene, respectively, under...
Aquaporins are natural proteins that rapidly transport water across cell membranes, maintaining homeostasis, whilst strictly excluding salt. This has inspired their use in purification and desalination, a critical emerging need. However, stability, scalability, cost have prevented widespread adoption membrane technologies. As such, attention turned to the of artificial channels, with pore functionalized polymers macrocycles providing powerful alternative. Whilst impressive rates been...
Ring-opening metathesis polymerization (ROMP) is a well-established method that uses strained cyclic olefins to produce polymers with controlled molecular weight and dispersity suitable for aggregation in solution, leading induced self-assembly (PISA). Herein, we report new norbornene-based monomers the living ROMP were synthesized on multigram scale (20 g) starting from cis-5-norbornene-exo-2,3-dicarboxylic anhydride hydrazine. Upon further reaction carboxylic acid chlorides,...
Indazoles are high value chemical building blocks used in medicinal chemistry and materials science for their distinct structural functional features. This study details a [3+2]‐cycloaddition reaction between various aryl‐ketodiazoesters ortho‐(trimethylsilyl)aryl triflates under mild conditions, leading predominantly to 1‐acyl‐1H‐indazoles. N‐aryl‐1H‐indazoles aryl benzoates were also observed as other products. The exhibits broad group tolerance scalability, making it valuable synthetic...
Aquaporins are natural proteins that rapidly transport water across cell membranes, maintaining homeostasis, whilst strictly excluding salt. This has inspired their use in purification and desalination, a critical emerging need. However, stability, scalability, cost have prevented widespread adoption membrane technologies. As such, attention turned to the of artificial channels, with pore functionalized polymers macrocycles providing powerful alternative. Whilst impressive rates been...
Aquaporins are natural proteins that rapidly transport water across cell membranes, maintaining homeostasis, whilst strictly excluding salt. This has inspired their use in purification and desalination, a critical emerging need. However, stability, scalability, cost have prevented widespread adoption membrane technologies. As such, attention turned to the of artificial channels, with pore functionalized polymers macrocycles providing powerful alternative. Whilst impressive rates been...
An efficient strategy for the synthesis of monoamine end-functionalized living polymers using ring-opening metathesis polymerization with ruthenium initiators is reported. A new end-capping agent this purpose was synthesized, and its efficiency end-functionalization evaluated two common ruthenium-based initiators. Finally, terminal cross-metathesis also explored as another alternative toward amine polymers, comparison between techniques presented.
Synthesis, characterization,<italic>in vitro</italic>cytotoxicity and catalytic potential of the dioxidovanadium(<sc>v</sc>) complexes azohydrazones.
Compartmentalization of metal ions is crucial in biology as well materials science. For the synthesis single source precursors, preorganization different particular interest for low-temperature generation mixed oxides. On basis a potentially Ω-shaped salen-type ligand providing an N2O2 O2O2 coordination site, compounds with Cu(II) or Ni(II) and alkali have been studied their structural optical properties. UV–vis 1H NMR titrations show that obtained adopt partially structures solution...