Koichi Yamada

ORCID: 0000-0002-4766-9380
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Antifungal resistance and susceptibility
  • Bacterial Identification and Susceptibility Testing
  • Antimicrobial Resistance in Staphylococcus
  • Antibiotics Pharmacokinetics and Efficacy
  • Fungal Infections and Studies
  • Pneumonia and Respiratory Infections
  • Thin-Film Transistor Technologies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Nosocomial Infections in ICU
  • Antibiotic Use and Resistance
  • Organic Electronics and Photovoltaics
  • COVID-19 Clinical Research Studies
  • Bacterial biofilms and quorum sensing
  • Cardiac Imaging and Diagnostics
  • Atomic and Subatomic Physics Research
  • Magnetism in coordination complexes
  • Geotechnical Engineering and Soil Stabilization
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Silicone and Siloxane Chemistry
  • Mycobacterium research and diagnosis
  • Long-Term Effects of COVID-19
  • Silicon and Solar Cell Technologies
  • Quantum optics and atomic interactions
  • Cold Atom Physics and Bose-Einstein Condensates

Bank of Japan
2024

Tokyo Metropolitan University
2003-2024

Osaka Metropolitan University
2022-2024

Osaka International University
2024

Kajima Corporation (Japan)
2018-2024

Kitami Institute of Technology
2024

Osaka City University Hospital
2015-2023

Osaka City University
1961-2022

Kumamoto University
2021

Kyoto University
1983-2020

Gate-voltage dependence of carrier mobility is measured in high-performance field-effect transistors rubrene single crystals by simultaneous detection the longitudinal conductivity ${\ensuremath{\sigma}}_{\ensuremath{\square}}$ and Hall coefficient ${R}_{H}$. The ${\ensuremath{\mu}}_{H}$ ($\ensuremath{\equiv}{\ensuremath{\sigma}}_{\ensuremath{\square}}{R}_{H}$) reaches nearly $10\text{ }\text{ }{\mathrm{cm}}^{2}/\mathrm{V}\text{ }\mathrm{s}$ when relatively low-density carriers...

10.1103/physrevlett.98.196804 article EN Physical Review Letters 2007-05-09

The proposed origin of the improved ORR activity is unlikely to be from residual metal impurities but creation topological defects caused by removal high temperature CO desorbing oxygen functional groups.

10.1039/c3ee43743d article EN Energy & Environmental Science 2014-01-01

A new measurement of the branching ratio R_{e/μ}=Γ(π^{+}→e^{+}ν+π^{+}→e^{+}νγ)/Γ(π^{+}→μ^{+}ν+π^{+}→μ^{+}νγ) resulted in R_{e/μ}^{exp}=[1.2344±0.0023(stat)±0.0019(syst)]×10^{-4}. This is agreement with standard model prediction and improves test electron-muon universality to level 0.1%.

10.1103/physrevlett.115.071801 article EN Physical Review Letters 2015-08-13

Nano-drilling of multiwalled carbon nanotubes (MWCNTs) has been conducted by taking advantage CoOx as the oxidation catalyst at a relatively low temperature 250 °C. An increase ID/IG ratio Raman spectroscopy, together with TEM visualization, justifies presence hole defects on sidewalls, in comparison to pristine and purified MWCNTs. Holes drilled basal plane MWCNTs could access into inner core observed N2 adsorption isotherm. Drilled (DMWCNTs) show largest quantity functional groups 5.4 ×...

10.1039/c2jm34684b article EN Journal of Materials Chemistry 2012-01-01

Favipiravir is an RNA polymerase inhibitor that showed strong antiviral efficacy in vitro and small-animal models of several viruses responsible for hemorrhagic fever (HF), including Ebola virus. The aim this work was to characterize the complex pharmacokinetics favipiravir nonhuman primates (NHPs) order guide future studies large-animal models. Four different were conducted 30 uninfected cynomolgus macaques Chinese (n = 17) or Mauritian 13) origin treated with intravenous 7 14 days...

10.1128/aac.01305-16 article EN Antimicrobial Agents and Chemotherapy 2016-10-11

Abstract Long-term sequelae of the coronavirus disease (COVID-19) constitute Long COVID. Although COVID has been reported globally, its risk factors and effects on quality life (QOL) remain unclear. We conducted a cross-sectional study using questionnaires electronic medical records COVID-19 patients who were diagnosed or hospitalized at five facilities in Japan. Responses obtained from 285 out 1,150 patients. More than half participants symptoms varying severity 1 year after COVID-19....

10.1038/s41598-022-25398-6 article EN cc-by Scientific Reports 2022-12-27

Abstract Although IL-10 has been implicated in the pathogenesis of several autoimmune diseases, mechanisms by which this cytokine mediates inflammatory lesions remain to be elucidated. Exocrine gland destruction is an important early step development Sjögren’s syndrome. To better understand role syndrome, we made transgenic mice mouse gene was regulated human salivary amylase promoter. Transgenic expression induced apoptosis glandular tissue and lymphocyte infiltration consisting primarily...

10.4049/jimmunol.162.5.2488 article EN The Journal of Immunology 1999-03-01

High-density carrier accumulation in organic semiconductors is demonstrated Au∕polymer gel electrolyte/rubrene crystal∕SiO2∕doped Si dual-gate transistors, forming electric double layers the polymer gel. Application of only 1.2V across electrolyte drastically enhances conductance rubrene single crystal with field-induced density up to ∼5×1013cm−2. Directly comparing transfer characteristics same device channel transistors revealed that achieved doping level beyond maximum SiO2-based...

10.1063/1.2186513 article EN Applied Physics Letters 2006-03-10

Abstract Novel metal‐complex assemblies constructed from the flexible hinge‐like ligand H 2 bhnq (H bhnq=2,2′‐bi(3‐hydroxy‐1,4‐naphthoquinone)) have been synthesized. The X‐ray crystal structures of these compounds reveal that four types architectures are accessible by variation metal ions. In copper( II ) 1 – 3 , chelating 2− ions bridge centers to form one‐dimensional zigzag chains. chains arranged hydrogen‐bonding interactions and stacking produce porous structures. Cobalt( zinc( 4 5...

10.1002/chem.200305640 article EN Chemistry - A European Journal 2004-04-23

Recently synthesized benzoannulated fused oligothiophenes and oligoselenophenes are introduced as air-stable organic semiconductors for high-performance field-effect transistors. To evaluate electronic mobility intrinsic to the materials, technique of single-crystal transistors is employed two representative compounds pentathienoacene f-B5TB its selenium analog f-BT3STB. High approximately 1.1cm2∕Vs achieved compound due considerable Se---Se orbital interactions. The materials simultaneously...

10.1063/1.2535617 article EN Applied Physics Letters 2007-02-12

We study theoretically and experimentally the effect of noise on Rydberg atoms passing through a strong coherent microwave field. derive master equation containing field exactly. Its solution reveals presence four universal dynamical regimes: (i) an initial classical regime, (ii) subsequent localized (iii) transition, induced by noise, in which coherence localization are destroyed, (iv) final where equidistribution over quasienergy states is reached.

10.1103/physrevlett.62.341 article EN Physical Review Letters 1989-01-23

Vascular calcification is an independent determinant of cardiovascular events in maintenance haemodialysis (HD) patients. It not known whether acute changes the serum calcium concentration before and after HD (DeltaCa) are associated with development aortic calcification.We enrolled 71 patients dialysed a dialysate 3.0 mEq/l determined their index (ACI) by abdominal computed tomography twice at interval 3 years. To identify factors contributing to rate progression calcification, we analysed...

10.1093/ndt/gfm031 article EN Nephrology Dialysis Transplantation 2007-03-29

Evidence of massive neutrinos in the ${\ensuremath{\pi}}^{+}\ensuremath{\rightarrow}{e}^{+}\ensuremath{\nu}$ decay spectrum was sought with background ${\ensuremath{\pi}}^{+}\ensuremath{\rightarrow}{\ensuremath{\mu}}^{+}\ensuremath{\rightarrow}{e}^{+}$ chain highly suppressed. Upper limits (90% C.L.) on neutrino mixing matrix element $|{U}_{ei}{|}^{2}$ mass region $60--129\text{ }\text{ }\mathrm{MeV}/{c}^{2}$ were set at level ${10}^{\ensuremath{-}8}$.

10.1103/physrevd.84.052002 article EN publisher-specific-oa Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D, Particles, fields, gravitation, and cosmology 2011-09-06

The Mycoses Forum in Japan has developed management bundles for candidaemia to incorporate into bedside practice. aim of this study was investigate nationwide compliance with the and their impact on clinical outcomes. Non-neutropenic patients treated antifungals were surveyed. Bundles consist nine items complete. Data sent central office between July 2011 April 2012. Six hundred eight analysed. rate achieving all elements 6.9%, it increased 21.4% when analysed by bundle except oral switch....

10.1093/jac/dku414 article EN cc-by-nc Journal of Antimicrobial Chemotherapy 2014-10-17

BackgroundThe pharmacokinetics and appropriate dose regimens of favipiravir are unknown in hospitalized influenza patients; such data also needed to determine dosage selection for trials COVID-19.MethodsIn this dose-escalating study, tolerability were assessed critically ill patients. Participants received one two dosing regimens; Japan licensed (1600 mg BID on day 1 600 the following days) higher (1800 mg/800 BID) trialed uncomplicated influenza. The primary pharmacokinetic endpoint was...

10.1016/j.ebiom.2020.103125 article EN cc-by-nc-nd EBioMedicine 2020-11-22

Pseudomonas aeruginosa bacteremia occurs mainly in immunocompromised patients. However, P. immunocompetent patients has also been reported. The aim of this study was to evaluate the clinical characteristics relation immune status medical records 126 adult with Nagasaki University Hospital were retrospectively reviewed between January 2003 and December 2012. Of bacteremia, 60 (47.6%) classified as immunocompetent. Mortality tended be lower than (7-day mortality, 8% vs. 30%, P < 0.01; 30-day...

10.7883/yoken.jjid.2014.573 article EN Japanese Journal of Infectious Diseases 2015-06-11

A few Japanese cases of hypermucoviscous Klebsiella pneumoniae (K. pneumoniae) invasive syndrome have recently been reported. Although extrahepatic complications from bacteremic dissemination observed, infected aneurysms are rare. Furthermore, the primary source infection is generally a liver abscess, and rarely prostate. Therefore, we report two atypical K. syndrome. The first case was an 81-year-old man with no significant medical history, who referred to our hospital for vision loss in...

10.1186/s12879-016-2011-3 article EN cc-by BMC Infectious Diseases 2016-11-16

Background The incidence of ocular candidiasis (OC) in patients with candidemia varies across different reports, and the issue whether routine ophthalmoscopy improves outcomes has been raised. This study investigated OC evaluate extent impacts clinical outcomes. Methods retrospective included non-neutropenic who underwent treatment at one 15 medical centers between 2010 2016. Chorioretinitis without other possible causes for lesions endophthalmitis was classified as a probable OC. If signs...

10.1371/journal.pone.0216956 article EN cc-by PLoS ONE 2019-05-23

The ethanol patch test, which is considered to be a cutaneous model of flushing, was performed on 311 healthy Japanese (237 adults and 74 children). By comparing the results with aldehyde dehydrogenase (ALDH) phenotype determined by isoelectric focusing from hair root samples, it demonstrated that test good indicator ALDH phenotype. usefulness this in future studies discussed.

10.1111/j.1530-0277.1989.tb00317.x article EN Alcoholism Clinical and Experimental Research 1989-04-01

A series of pyrene derivatives containing thienyl groups, 1−3, has been prepared using the Suzuki coupling reaction. Recrystallization from solution and physical vapor transport (PVT) method afforded different types crystals 1. From mixture isomers 2, 1,8-isomer preferably crystallized solution, whereas 1,6-isomer crystal was obtained by PVT method. Fabricating single-crystal-based field-effect transistors above compounds we directly compared performance between devices two isoforms 1 those...

10.1021/cm703499q article EN Chemistry of Materials 2008-06-28
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