A5084700265- Regulation of Appetite and Obesity
- Diet and metabolism studies
- Pain Mechanisms and Treatments
- Adipose Tissue and Metabolism
- Biochemical Analysis and Sensing Techniques
- Temporomandibular Joint Disorders
- Sleep and Wakefulness Research
- Neuroendocrine regulation and behavior
- Neuropeptides and Animal Physiology
- Stress Responses and Cortisol
- Neurotransmitter Receptor Influence on Behavior
- Circadian rhythm and melatonin
- Botulinum Toxin and Related Neurological Disorders
- Hypothalamic control of reproductive hormones
- Osteoarthritis Treatment and Mechanisms
- Neuroscience of respiration and sleep
- Biochemical effects in animals
- Child Nutrition and Feeding Issues
- Neuroscience and Neuropharmacology Research
- Salivary Gland Disorders and Functions
- Olfactory and Sensory Function Studies
- Herpesvirus Infections and Treatments
- Nicotinic Acetylcholine Receptors Study
- Growth Hormone and Insulin-like Growth Factors
- Birth, Development, and Health
Texas A&M University
2003-2019
Gaston College
2006-2018
Baylor University
1981-2017
Texas A&M Health Science Center
2007-2014
Baylor College of Medicine
1979-2012
University of Texas Health Science Center at Dallas
2010
Texas A&M University System
1998-2007
Michigan State University
2000
Florida State University
1996
Syracuse University
1996
After rats had adapted to regular meal feeding in the morning they demonstrated an altered circadian rhythm of plasma corticosterone (B) even under normal light-dark cycle. The daily B consisted two peaks, with one peak at 08.00 h anticipation and a second corresponding prior lights-off seen ad libitum-fed animals. Neither meal-fed animals achieved magnitude single observed control In spite some quantitative differences during certain periods day, after there was no difference basic profile...
Weanling rats received bilateral electrolytic lesions in the dorsomedial (DMH) or ventromedial (VMH) hypothalamic areas destroying primarily (DMN) (VMN) nuclei. Sham-operated served as controls. Lesions VMN and DMN, both of which have previously been shown to disrupt normal diurnal feeding rhythms, were also observed plasma corticosterone rhythms present study. The a.m. values DMN-lesioned higher than sham-operated In p.m., VMN- lower those controls but unchanged comparison their own...
The effects of short term food deprivation on circadian plasma insulin, growth hormone, corticosterone and glucose patterns were studied in male rats. Insulin the fed controls increased significantly during latter part light phase as previously reported. fasted rats also but levels below animals. late afternoon increase insulin animals was not being driven by rhythms appeared responsive to changes. Growth hormone prolactin elevated fasting day compared Corticosterone similar
A greater incidence of temporomandibular joint (TMJ) pain is reported in females, suggesting that gonadal hormones may play a role this condition. However, the exact roles 17β-estradiol (E2) and progesterone (P4) TMJ are not completely known. Two experiments were performed to determine separate E2 P4 nociception at various stages estrous cycle. Ovariectomized (OVX) rats cycled with physiological concentrations or P4. The E2-cycled then received bilateral injections saline (SAL) complete...
Neuropathic pain represents a challenge to clinicians because it is resistant commonly prescribed analgesics due its largely unknown mechanisms. Here, we investigated descending dopaminergic pathway-mediated modulation of trigeminal neuropathic pain. We performed chronic constriction injury the infraorbital nerve from maxillary branch induce in mice. Our retrograde tracing showed that projection hypothalamic A11 nucleus spinal caudalis bilateral. Optogenetic/chemogenetic manipulation...
Hypophysectomy altered but did not abolish the rats' normal diurnal feeding rhythm. The ingestive rhythm of castrated male rats was comparable to shams. Adrenalectomy attenuate slightly depress water intake Thyroidectomy in a magnitude hypophysectomy modified animals' While thyroidectomy also it so lesser degree than hypophysectomy. These data suggest that thyroid secretions may be partially responsible for maintenance and extent rats.
The glucoprivation effects of 2-deoxy-D-glucose (2DG) on feeding behavior were studied in rats with bilateral lesions the dorsomedial hypothalamic nucleus (DMN) and sham-operated controls. lesioned injected intraperitoneally 2DG (5% wt/vol) at doses either 150 mg/kg, 300 or 500 saline ("control days"). At all significantly more ate showed an increased food consumption during first few hours after injection when compared to control days. However, their 24-h was normal less than normal,...
Females report temporomandibular joint (TMJ) pain more than men and studies suggest estrogen modulates this response. Our goal in study was to determine genes that are modulated by physiological levels of 17β-estradiol could have a role TMJ pain. To complete goal, saline or Freund's adjuvant injected the when plasma low it at high proestrus level. TMJ, trigeminal ganglion, subnucleus caudalis/upper cervical cord junction (Vc/C(1-2) ) tissues were isolated from treated rats expression 184...