Todd L. Demmy

ORCID: 0000-0002-4800-2297
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Pleural and Pulmonary Diseases
  • Lung Cancer Treatments and Mutations
  • Tracheal and airway disorders
  • Gastric Cancer Management and Outcomes
  • Mechanical Circulatory Support Devices
  • Lung Cancer Research Studies
  • Esophageal Cancer Research and Treatment
  • Esophageal and GI Pathology
  • Medical Imaging and Pathology Studies
  • Head and Neck Cancer Studies
  • Cancer Diagnosis and Treatment
  • Trauma Management and Diagnosis
  • Radiomics and Machine Learning in Medical Imaging
  • Airway Management and Intubation Techniques
  • Cardiac Structural Anomalies and Repair
  • Transplantation: Methods and Outcomes
  • Cardiac, Anesthesia and Surgical Outcomes
  • Congenital Diaphragmatic Hernia Studies
  • Occupational and environmental lung diseases
  • Myasthenia Gravis and Thymoma
  • Surgical site infection prevention
  • Cardiac and Coronary Surgery Techniques
  • Global Cancer Incidence and Screening
  • Pneumothorax, Barotrauma, Emphysema

Roswell Park Comprehensive Cancer Center
2015-2024

Memorial Sloan Kettering Cancer Center
2024

University at Buffalo, State University of New York
2012-2023

Buffalo State University
2005-2023

The University of Texas Southwestern Medical Center
2020

Southwestern Medical Center
2020

Peking Union Medical College Hospital
2018-2019

Zhongnan Hospital of Wuhan University
2019

Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2019

Massachusetts General Hospital
2019

We undertook to determine whether adjuvant vinorelbine plus cisplatin prolongs overall survival among patients with completely resected early-stage non-small-cell lung cancer.We randomly assigned stage IB or II cancer observation. The primary end point was survival; principal secondary points were recurrence-free and the toxicity safety of regimen.A total 482 underwent randomization (242 patients) observation (240); 45 percent had pathological disease 55 II, all an Eastern Cooperative...

10.1056/nejmoa043623 article EN New England Journal of Medicine 2005-06-22

To evaluate the technical feasibility and safety of video-assisted thoracic surgery (VATS) lobectomy for small lung cancers.The Cancer Leukemia Group B 39802 trial was a prospective, multi-institutional study designed to elucidate VATS in early non-small-cell cancer (NSCLC) using standard definition (one 4- 8-cm access two 0.5-cm port incisions) that mandated videoscopic guidance traditional hilar dissection without rib spreading. Between 1998 2001, 128 patients with peripheral nodules < or...

10.1200/jco.2007.12.6649 article EN Journal of Clinical Oncology 2007-10-30

These NCCN Guidelines Insights focus on recent updates to the 2015 for Non-Small Cell Lung Cancer (NSCLC). Appropriate targeted therapy is very effective in patients with advanced NSCLC who have specific genetic alterations. Therefore, it important test tumor tissue from determine whether they alterations that make them candidates therapies. describe different testing methods currently available determining 2 most commonly actionable alterations, notably anaplastic lymphoma kinase (ALK) gene...

10.6004/jnccn.2015.0071 article EN Journal of the National Comprehensive Cancer Network 2015-05-01

Most patients with non–small cell lung cancer (NSCLC) are diagnosed advanced cancer. These guidelines only include information about stage IV NSCLC. Patients widespread metastatic disease (stage IV) candidates for systemic therapy, clinical trials, and/or palliative treatment. The goal is to identify before initiating aggressive treatment, thus sparing these from unnecessary futile If discovered during surgery, then extensive surgery often aborted. Decisions treatment should be based on...

10.6004/jnccn.2012.0130 article EN Journal of the National Comprehensive Cancer Network 2012-10-01

Video-assisted thoracoscopic surgery (VATS) lobectomy has been gradually accepted as an alternative surgical approach to open thoracotomy for selected patients with non-small-cell lung cancer (NSCLC) over the past 20 years. The aim of this project was standardize perioperative management VATS through expert consensus and provide insightful guidance clinical practice.A panel 55 experts on identified by Scientific Secretariat International Committee '20th Anniversary Lobectomy Conference-The...

10.1093/ejcts/ezt463 article EN European Journal of Cardio-Thoracic Surgery 2013-10-14

This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Non-Small Cell Lung Cancer (NSCLC) focuses on principles of radiation therapy (RT), which include following: (1) general early-stage, locally advanced, and advanced/metastatic NSCLC; (2) target volumes, prescription doses, normal tissue dose constraints advanced/palliative RT; (3) RT simulation, planning, delivery. Treatment recommendations should be made by a multidisciplinary team, including...

10.6004/jnccn.2014.0176 article EN Journal of the National Comprehensive Cancer Network 2014-12-01

Masses in the anterior mediastinum can be neoplasms (eg, thymomas, thymic carcinomas, or lung metastases) non-neoplastic conditions intrathoracic goiter). Thymomas are most common primary tumor mediastinum, although they rare. Thymic carcinomas very and originate thymus. Although thymomas spread locally, much less invasive than carcinomas. Patients with have 5-year survival rates of approximately 78%. However, for only 40%. These guidelines outline evaluation, treatment, management these...

10.6004/jnccn.2013.0072 article EN Journal of the National Comprehensive Cancer Network 2013-05-01

Lung cancer is still the leading cause of death worldwide, and non-small cell lung accounts for 80% to 85% all cases. Surgery, radiation therapy, chemotherapy are 3 modalities commonly used treat patients with NSCLC can be either alone or in combination depending on disease status. The 2006 NCCN Non-Small Cell Cancer Guidelines provide latest updates management this disease, including stage regrouping changes screening recommendations high-risk treatment several stages. In addition,...

10.6004/jnccn.2006.0046 article EN Journal of the National Comprehensive Cancer Network 2006-07-01

The optimal strategy to achieve palliation of malignant pleural effusions (MPEs) is unknown. This multi-institutional, prospective, randomized trial compares 2 established methods for controlling symptomatic unilateral MPEs. Patients with MPEs were either daily tunneled catheter drainage (TCD) or bedside talc pleurodesis (TP). patterned after a previous that showed TP was equivalent thoracoscopic (CALGB 9334). primary end point the current study combined success: consistent/reliable...

10.6004/jnccn.2012.0102 article EN Journal of the National Comprehensive Cancer Network 2012-08-01

Despite experimental advantages for certain heart preservation solutions (HPS), their clinical popularity and related survival are uncertain. We surveyed all active UNOS transplant centers to determine HPS. HPS benefits were tested using the registry. Centers used from 1 3 types of 167 solutions. Of these formulations, 55.1% commonly cited The other (custom) mixtures differed those usually reported. All classified as intracellular (I, [Na++] < 70 mEq/L) or extracellular (E, ≥ mEq/L)....

10.1097/00007890-199701270-00015 article EN Transplantation 1997-01-01
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