A5048205568- Vaccine Coverage and Hesitancy
- Viral gastroenteritis research and epidemiology
- Healthcare Policy and Management
- Hepatitis Viruses Studies and Epidemiology
- Primary Care and Health Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Emergency and Acute Care Studies
- Pneumonia and Respiratory Infections
- Clinical practice guidelines implementation
- Global Maternal and Child Health
- Urinary Bladder and Prostate Research
- Patient Satisfaction in Healthcare
- Delphi Technique in Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Congenital Anomalies and Fetal Surgery
- Pelvic floor disorders treatments
- Sepsis Diagnosis and Treatment
- Global Health Care Issues
- Bacterial Infections and Vaccines
- Cardiac, Anesthesia and Surgical Outcomes
- Influenza Virus Research Studies
- COVID-19 epidemiological studies
- Prostate Cancer Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Meta-analysis and systematic reviews
London School of Hygiene & Tropical Medicine
2012-2023
Faculty of Public Health
2013-2023
The University of Texas Southwestern Medical Center
2021
University of London
1999-2018
Forum international des transports
2014
Northern General Hospital
2009
Universidad de Londres
2002
United Nations Industrial Development Organization
2002
MRC Biostatistics Unit
1998
The University of Western Australia
1998
T he overall aim of the NHS R&D Health Technology Assessment (HTA) programme is to ensure that high-quality research information on costs, effectiveness and broader impact health technologies produced in most efficient way for those who use, manage
<h3>Abstract</h3> <b>Objective:</b> To determine to what extent institutions carrying out in vitro fertilisation can reasonably be ranked according their live birth rates. <b>Design:</b> Retrospective analysis of prospectively collected data on rate after fertilisation. <b>Setting:</b> 52 clinics the United Kingdom over period April 1994 March 1995. <b>Main outcome measure:</b> Estimated adjusted for each clinic; rank and its associated uncertainty. <b>Results:</b> There were substantial...
To investigate whether the size of workforce (nurses, doctors and support staff) has an impact on survival chances critically ill patients both in intensive care unit (ICU) hospital. Investigations outcomes suggest that some variation patient rates might be related to staffing levels workload, but evidence is still equivocal. Information about patients, including outcome (whether lived or died) came from Intensive Care National Audit & Research Centre (ICNARC) Case Mix Programme. An...
Background Rotavirus is a leading cause of diarrhoeal mortality in children but there considerable disagreement about how many deaths occur each year. Methods and findings We compared CHERG, GBD WHO/CDC estimates age under 5 years (U5) rotavirus at the global, regional national level using standard year (2013) list 186 countries. The global were 157,398 (CHERG), 122,322 (GBD) 215,757 (WHO/CDC). three groups used different methods: (i) to select data points for rotavirus-positive proportions;...
Vaccination is one of the most effective public health interventions. We investigate impact vaccination activities for
The aim of the study was to assess reproducibility clinical coding in two National Health Service hospitals within North West Thames region. A retrospective audit carried out, hospital episode statistics, involving comparison codes assigned by local staff with those members an external team unaware locally codes. Where and coders disagreed, records were reviewed for a third time further independent coder. subjects random sample 1607 non-maternity, non-psychiatric admissions occurring between...
<h3>Abstract</h3> <b>Objective</b> To investigate the relation between older patients9 assessments of quality their primary care and measures good clinical practice on basis data from administrative records. <b>Design</b> Cross sectional population based study using general assessment survey. <b>Setting</b> 18 practices in Basildon trust area, south east England. <b>Participants</b> 3487 people aged 65 or more. <b>Main outcome measures</b> Correlations mean scores survey three evidence case...
<b>Objective</b> To determine whether clinicians9 prognoses in patients with severe acute exacerbations of obstructive lung disease admitted to intensive care match observed outcomes terms survival. <b>Design</b> Prospective cohort study. <b>Setting</b> 92 units and three respiratory high dependency the United Kingdom. <b>Participants</b> 832 aged 45 years older breathlessness, failure, or change mental status because an exacerbation COPD, asthma, a combination two. <b>Main outcome...
To compare two consensus development methods commonly used for developing clinical guidelines in terms of the judgments produced, closeness consensus, amount change between rounds, concordance with research evidence and reliability.In all, 213 general practitioners mental health professionals from England participated four Delphi nominal groups. They rated appropriateness treatments (cognitive behavioural therapy [CBT], [BT], brief psychodynamic interpersonal [BPIT] antidepressants) three...
To estimate the effect of prompt admission to critical care on mortality for deteriorating ward patients.We performed a prospective cohort study consecutive patients assessed care. Prompt admissions (within 4 h assessment) were compared 'watchful waiting' cohort. We used strain (bed occupancy) as natural randomisation event that would predict transfer Strain was classified low, medium or high (2+, 1 0 empty beds). This instrumental variable (IV) analysis repeated subgroup referrals with...
Infant rotavirus vaccines have led to substantial reductions in hospital admissions and deaths due gastroenteritis, but some studies reported an elevated risk of intussusception, a rare bowel disorder. This analysis aimed provide evidence on the potential mortality reduction benefits intussusception risks current vaccination schedules, explore whether alternative schedules could advantages.All 135 low-income middle-income countries, defined by gross national income per capita less than US$12...
Previous studies have found rotavirus vaccination to be highly cost-effective in low-income countries. However, updated evidence is now available for several inputs (ie, disease mortality rates, age distributions, vaccine timeliness, and efficacy by duration of follow-up), new vaccines entered the market, prices decreased, cost-effectiveness thresholds been re-examined. We aimed provide estimates inform national decisions about introduction current use Gavi