Hui‐Ling Lai

ORCID: 0000-0002-4853-981X
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About
Contact & Profiles
Research Areas
  • Music Therapy and Health
  • Sleep and related disorders
  • Neuroscience and Music Perception
  • Sleep and Wakefulness Research
  • Pediatric Pain Management Techniques
  • Family Support in Illness
  • Cancer survivorship and care
  • Sleep and Work-Related Fatigue
  • Intensive Care Unit Cognitive Disorders
  • Empathy and Medical Education
  • Nursing education and management
  • Complementary and Alternative Medicine Studies
  • Health and Well-being Studies
  • Health and Wellbeing Research
  • Workplace Health and Well-being
  • Childhood Cancer Survivors' Quality of Life
  • Psychosomatic Disorders and Their Treatments
  • Infant Development and Preterm Care
  • Healthcare professionals’ stress and burnout
  • Health, psychology, and well-being
  • Diabetes Management and Research
  • Obstructive Sleep Apnea Research
  • Simulation-Based Education in Healthcare
  • Ovarian cancer diagnosis and treatment
  • Chronic Disease Management Strategies

Sixth Affiliated Hospital of Sun Yat-sen University
2022-2025

Sun Yat-sen University
2020-2025

Jiangxi Provincial People's Hospital
2024

Tzu Chi University
2013-2023

The First Affiliated Hospital, Sun Yat-sen University
2020-2023

Guangzhou Vocational College of Science and Technology
2022

Huazhong University of Science and Technology
2015-2019

Tongji Hospital
2015-2019

Buddhist Tzu Chi General Hospital
2004-2017

Cancer Research Center
2015

Aim. The aim of this paper is to report an investigation the effects soft music on sleep quality in older community‐dwelling men and women Taiwan. Background. Sleep a complex rhythmic state that may be affected by ageing process. Few studies have focused music, non‐pharmacological method improving adults. Method. A randomized controlled trial was used with two‐group repeated measures design. Sixty people aged 60–83 years difficulty sleeping were recruited through community leaders screened...

10.1111/j.1365-2648.2004.03281.x article EN Journal of Advanced Nursing 2005-01-19

Currently, targeting the autophagic pathway is regarded as a promising new strategy for cancer drug discovery. Here, we screened North China Pharmaceutical Group Corporation's pure compound library of microbial origin using GFP-LC3B-SKOV3 cells and identified elaiophylin novel autophagy inhibitor. Elaiophylin promotes autophagosome accumulation but blocks flux by attenuating lysosomal cathepsin activity, resulting in SQSTM1/p62 various cell lines. Moreover, destabilizes lysosomes indicated...

10.1080/15548627.2015.1017185 article EN Autophagy 2015-05-28

Finely tuned mitogen-activated protein kinase (MAPK) signaling is important for cancer cell survival. Perturbations that push cells out of the MAPK fitness zone result in death. Previously, a screen North China Pharmaceutical Group Corporation's pure compound library microbial origin, we identified elaiophylin as an autophagy inhibitor. Here, demonstrated new role inducing excessive endoplasmic reticulum (ER) stress, ER-derived cytoplasmic vacuolization, and consequent paraptosis by...

10.1038/s41392-022-01131-7 article EN cc-by Signal Transduction and Targeted Therapy 2022-09-12

We investigated the effects of relaxation, music, and combination relaxation music on postoperative pain, across between two days activities (ambulation rest) ambulation each day. This secondary analysis a randomized controlled trial was conducted from 1995 to 1997.After surgery, patients do not always receive sufficient relief opioids may have undesired side-effects. More complete (10-30%) found recently with adjuvant interventions their combination. Comparison treatments been examined...

10.1046/j.1365-2648.2001.01655.x article EN Journal of Advanced Nursing 2001-01-26

Abstract Aim The purpose was to examine the effects of non‐commercial music on quality sleep and relaxation indices, including heart rate, mean arterial pressure, respiratory rate in patients intensive care units. Background There is currently insufficient scientific knowledge for critically ill patients. Design A randomized controlled trial. Methods Between January–December 2010, 28 aged 39–78 years were randomly assigned control groups. Participants groups listened 45 minutes at nocturnal...

10.1111/j.1365-2648.2012.06130.x article EN Journal of Advanced Nursing 2012-08-29

The research aimed to investigate the effectiveness of cupping therapy (CT) in changes on skin surface temperature (SST) for relieving chronic neck and shoulder pain (NSP) among community residents. A single-blind experimental design constituted sixty subjects with self-perceived NSP. were randomly allocated two groups. group received CT at SI 15, GB 21, LI 15 acupuncture points, control no intervention. Pain was assessed using SST, visual analog scale (VAS), blood pressure (BP). main...

10.1155/2016/7358918 article EN cc-by Evidence-based Complementary and Alternative Medicine 2016-01-01

lai h.-l. & li y.-m. (2011) The effect of music on biochemical markers and self-perceived stress among first-line nurses: a randomized controlled crossover trial. Journal Advanced Nursing67(11), 2414–2424. Abstract Aim. aim this study was to examine the effects indices association between preference stress. Background. Although clinical studies have demonstrated effectiveness stress, results been inconsistent. At time writing, no known publications had investigated preferred workers in...

10.1111/j.1365-2648.2011.05670.x article EN Journal of Advanced Nursing 2011-06-07

Resilience has been associated with psychological adaptation to many threatening life events, but previous studies have rarely analysed the integrated relationships among demographic and disease characteristics various health outcomes in Taiwan. This study examined associations factors, characteristics, resilience, coping styles adverse outcomes, including anxiety depressive symptoms sleep disorders.A descriptive, cross-sectional design was used. Data from a convenience sample of 175...

10.1111/ecc.13161 article EN European Journal of Cancer Care 2019-09-01

10.1016/j.apnu.2004.07.007 article EN Archives of Psychiatric Nursing 2004-10-01

Objectives. The purpose of this randomised investigator‐blind controlled trial is to examine the effects music on state anxiety and physiological indices among patients undergoing root canal treatment. Design. Randomised trial. Methods. Purposive sampling was used recruit 44 adult subjects. subjects were randomly assigned treatment control group. There 22 in each Subjects group listened selected sedative using headphones throughout procedure. worn but without music. Using a repeated measures...

10.1111/j.1365-2702.2008.02350.x article EN Journal of Clinical Nursing 2008-09-17

The aim of this study was to understand the factors related intention leave their job among intensive care unit (ICU) nurses in eastern Taiwan and make between-group comparisons between an stay as well predict influencing that affect ICU staff nurses' leave.Nurses' may have important impact on actual turnover nurses. issue has always been concern nursing executives. Only limited empirical studies area investigated Asian culture context particularly region.A cross-sectional predictive...

10.1111/j.1365-2702.2007.02180.x article EN Journal of Clinical Nursing 2008-04-22

This study determined the prevalence of and factors associated with insomnia in rotating-shift nurses. A two-stage, cross-sectional, hospital-based was conducted eastern Taiwan. Participants were randomly-sampled, nurses (n = 661), ranging age from 21 to 62 years, a mean 31.86 (standard deviation 8.09). Insomnia disorder identified using Pittsburgh Sleep Quality Index. Nurses completed self-reported Index, together other questionnaires designed by researchers for purpose study. The 59% 390)....

10.1111/j.1442-2018.2011.00641.x article EN Nursing and Health Sciences 2011-10-20

In Brief Background and Objectives: Cardiovascular diseases are the number 1 cause of death globally. Cardiac catheterization is a key step in diagnosis management cardiovascular diseases. Decreasing stress cardiac factor improving patients' well-being. The aim study was to explore effect music on psychophysiological indices patients awaiting examination. Methods: Using 2-group repeated-measures design, 54 subjects aged 47 70 years scheduled for examination were recruited. randomly assigned...

10.1097/jcn.0b013e3181fb711b article EN The Journal of Cardiovascular Nursing 2011-09-01

Although ovarian cancer, a gynecological malignancy, has the highest fatality rate, it still lacks highly specific biomarkers, and differential diagnosis of masses remains difficult to determine for gynecologists. Our study aimed obtain cancer-specific protein candidates from circulating small extracellular vesicles (sEVs) develop panel cancer screening masses. In our study, sEVs derived serum healthy controls patients with cystadenoma were investigated proteomic profile. discovery cohort,...

10.3390/cancers14153719 article EN Cancers 2022-07-30

10.1016/j.gerinurse.2004.08.009 article EN Geriatric Nursing 2004-09-01

Aim. The aim of this paper is to report an investigation the effects soft music on sleep quality in older community‐dwelling men and women Taiwan. Background. Sleep a complex rhythmic state that may be affected by ageing process. Few studies have focused music, non‐pharmacological method improving adults. Method. A randomized controlled trial was used with two‐group repeated measures design. Sixty people aged 60–83 years difficulty sleeping were recruited through community leaders screened...

10.1111/j.1365-2648.2006.03693.x article EN Journal of Advanced Nursing 2006-01-01

Abstract Aim The present authors examined the effects of listening to music on psychophysiological parameters (blood pressure, heart rate, and respiratory rate) during preoperative postoperative days determined whether could lower pain intensity opioid dosage in patients who underwent total knee replacements. Methods This was a two group repeated measures design for 30 subjects aged 53–85 years were scheduled replacement. Subjects randomly assigned either or control group....

10.1111/jjns.12070 article EN Japan Journal of Nursing Science 2015-03-09

Most psychosocial interventions among individuals with Type 2 diabetes mellitus (T2DM) target depressive symptoms (DSs) rather than causal antecedents that lead to DSs or affect health-related quality of life (HrQoL). This research investigated a conceptual model the effects risk factors and coping styles on HrQoL in patients T2DM.A descriptive, correlational design was used convenience sample 241 adults T2DM aged ≥ 20 years recruited from hospital metabolic outpatient department. Data were...

10.1177/1099800415569845 article EN Biological Research For Nursing 2015-02-10
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