A5052776207- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- Pediatric health and respiratory diseases
- Healthcare and Venom Research
- Insect and Pesticide Research
- Immunodeficiency and Autoimmune Disorders
- Neonatal Respiratory Health Research
- Respiratory and Cough-Related Research
- Streptococcal Infections and Treatments
- Nerve injury and regeneration
- Inhalation and Respiratory Drug Delivery
- Pneumonia and Respiratory Infections
- Signaling Pathways in Disease
- MicroRNA in disease regulation
- Mining and Industrial Processes
- Inflammasome and immune disorders
- T-cell and B-cell Immunology
- Viral-associated cancers and disorders
- Neuropeptides and Animal Physiology
- Nutrition and Health Studies
- Urticaria and Related Conditions
- Plant Disease Resistance and Genetics
- Agriculture, Plant Science, Crop Management
Poznan University of Medical Sciences
2011-2024
Centrum Onkologii
2001
MicroRNAs are small non-coding RNAs that regulate immune response and inflammation. We assumed miRNAs may be involved in the during cystic fibrosis pulmonary exacerbations (CFPE) altered expression profile airways blood underlie clinical outcomes CF pediatric patients. Methods: included 30 patients diagnosed with fibrosis. The biologic material (blood, sputum, exhaled breath condensate) was collected exacerbation stable condition. miRNA from sputum (n = 6) done using next-generation...
Venom allergy, though rare, may seriously influence health-related quality of life (HRQoL). There is a paucity research on HRQoL adolescents and young adults with Hymenoptera venom allergy. The aim was to assess the level evaluate its independent predictors in Polish treated immunotherapy.A multicenter cross-sectional study based Vespid Allergy Quality Life Questionnaire (VQLQ) adapted for used. sample included 87 patients (14-21 years) studied at different stages immunotherapy (VIT)....
Asthma is a heterogenous complex disorder caused by chronic inflammation of the airways. The key issue in genetic association studies disorders identification multiple low-risk genes that individually have little impact on phenotype, but combination account for clinical manifestation asthma. Since neurogenic emerging as candidate factor pathogenesis asthma, aim study was to investigate whether variants neurotrophin are associated with asthma disease severity or asthma-related phenotypes...
Interleukin-1 is a pro-inflammatory cytokine found in two forms (α and β). The α form mainly cell-bound, whereas IL-1β primarily secreted by macrophages response to immune system stimulation. We hypothesized that polymorphic variants of interleukin 1 genes may play role childhood asthma risk. aim this study was investigate if IL-1α β polymorphism associated with pediatric population the genotype affects its serum level.The studied included 310 children aged 6-18 years old (152 158 healthy...
Griscelli syndrome type 2 (GS2) is a rare autosomal-recessive disorder associated with RAB27A gene mutation, and clinically manifesting as hypopigmentation, disseminated chronic encephalitis, severe immunological disorders characterized by an accelerated hematological phase, also referred to hemophagocytic (HS), or lymphohistiocytosis (HLH). The authors report the diagnosis of GS2 in 11-year-old girl immunodeficiency, hepatosplenomegaly, neurological impairments, fatal multiorgan failure. In...
Hymenoptera venom allergy is one of the most frequent causes anaphylaxis. In its severe form, reaction to wasp and honey bee stings may be life-threatening. Therefore, immediate proper diagnosis implementation suitable therapy are extremely important. Broadening knowledge on mechanism allergic contribute improvement both diagnostic treatment methods. Thus, this study aimed discover changes in protein expression serum patients (wasp honeybee) point out proteins peptides involved inflammation....
1. Muller UR. Bee venom allergy in beekeepers and their family members. Curr Opin Allergy Clin Immunol. 2005; 5(4): 343–347. CrossRef Google Scholar
Hymenoptera venom allergy significantly affects the quality of life. Due to divergences in results available test and clinical symptoms patients, current widely applied diagnostic methods are often insufficient classify patients for immunotherapy (VIT). Therefore it is still needed search new, more precise, accurate methods. Hence, this research aimed discover new biomarkers a group inflammation factors using set multi-marker Bioplex panel. The adoption novel methodology based on...
The aim of the study was to assess immune response honeybee venom in relation degree exposure, time after a sting and clinical symptoms.Fifty-four volunteers were divided into 2 groups: beekeepers control group. serum levels total IgE (tIgE), bee venom-specific (venom sIgE), phospholipase A2-specific (phospholipase A2 tryptase IgG4 sIgG4) determined. In beekeepers, diagnostic tests performed within 3 hours following repeated minimum 6 weeks from last sting. individuals group, only once,...
W miarę rozwoju metod diagnostycznych pojawia się potrzeba tworzenia precyzyjnych zasad wykonywania badań [...]
Copeptin was found to be a stable biomarker of inflammation and stress response in cardiac, renal, metabolic, respiratory conditions such as pneumonia. The aim this study investigate the copeptin levels biological fluids (serum sputum supernatant) cystic fibrosis pediatric patients during pulmonary exacerbation remission possible influence on disease severity quality life. serum concentrations were measured 28 (CF) patients: 13 condition 15 exacerbation. In 10 CF patients, also sputum. all...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Oleś D, Szczepankiewicz A, Wołuń-Cholewa M, et al. Original paperDoes concentration influence viability of the bronchial epithelial cell line chronically exposed to antiasthmatic drugs?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2012;29(5):363-368. doi:10.5114/pdia.2012.31489. APA Oleś, D., Szczepankiewicz, A., Wołuń-Cholewa, M., Butowska, W., Sobkowiak, P., & Kycler, Z....
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Szczawińska-Popłonyk A, Jończyk-Potoczna K, Kycler Z, Bręborowicz A. Clinical immunologyBronchiectasis in children with primary immune deficiency diseases. Central European Journal of Immunology. 2012;37(4):371-377. doi:10.5114/ceji.2012.32728. APA Szczawińska-Popłonyk, A., Jończyk-Potoczna, K., Kycler, Z., & Bręborowicz, (2012). Immunology, 37(4), 371-377. https://doi.org/10.5114/ceji.2012.32728 Chicago...