- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Healthcare Policy and Management
- Global Health Care Issues
- Economic and Financial Impacts of Cancer
- Healthcare cost, quality, practices
- Biosimilars and Bioanalytical Methods
- Primary Care and Health Outcomes
- Employment and Welfare Studies
- Monoclonal and Polyclonal Antibodies Research
- Pharmaceutical industry and healthcare
- Cardiac Arrhythmias and Treatments
- Health disparities and outcomes
- Blood Pressure and Hypertension Studies
- CAR-T cell therapy research
- Healthcare Systems and Reforms
- Renal cell carcinoma treatment
- Renal and related cancers
- Cardiac Valve Diseases and Treatments
- Pneumonia and Respiratory Infections
- Injury Epidemiology and Prevention
- Patient Satisfaction in Healthcare
- Emergency and Acute Care Studies
- Pineapple and bromelain studies
- HER2/EGFR in Cancer Research
University of Nicosia
2017-2024
Nicosia General Hospital
2015-2024
National Health Insurance Service
2023
American Pharmacists Association
2022
University Medical Center Groningen
2022
University of Groningen
2022
European University Cyprus
2015-2019
Pharmac
2017
Open University of Cyprus
2013-2016
Larnaca College
2014-2016
The efficacy of intraaortic counterpulsation (IABP) in severe cardiogenic shock after acute myocardial infarction is questioned because the lack a large controlled series. Out 52 patients treated for severe, prolonged 3 improved with 'conventional' treatment. Forty-nine did not improve and were 'intractable' an average 10.74 +/- 7.14 h (means SD). Of these, 34 IABP. Ten survived longer than month. remaining 15 similar age, severity duration shock, whom balloon could be made to operate, none...
The objective of the study was to describe incidence pneumococcal nasopharyngeal carriage, serotype distribution and antibiotic resistance profile isolates in healthy children aged 6 36 months following implementation conjugate vaccines. A swab collected from 1105 a stratified random sampling between September 2013 April 2014. Demographics, vaccination status data on possible risk factors were recorded. Isolates serotyped tested for susceptibility. carriage rate 25.3%. Among enrolled, 393...
The pharmaceutical market in Cyprus has been characterised by high volume and a steep increase per-capita expenditure over the past decade. Most importantly, is fragmented due to absence of universal health insurance, uninsured have rely exclusively on private market. objective this study examine weaknesses Cypriot before financial crisis; discuss measures recently introduced after recommendations Troika; propose interventions that can improve access pharmaceuticals efficiency without...
SummaryAs Cyprus signed a financial agreement with team of international lenders, several reform measures were outlined as pre-requisites for disbursement instalments. The health sector was massively reformed in order to enhance efficiency and reduce waste. magnitude reforms included introduction guidelines clinical algorithms, co-payments, revision criteria public beneficiary status. In safeguard equity access, solidarity coverage sustainability its healthcare sector, must continue unabated...
The objective of this study is to assess the cost effectiveness sorafenib as a second line treatment advanced renal cell carcinoma compared standard best supportive care (BSC) in Cyprus. A probabilistic Decision analytic Markov Model was created simulate disease progression and data from landmark trials were used. Actual local costs set according current guidelines incremental per quality adjusted life year versus BSC €102,059. probability be effective at threshold €60,000 0%. Total...
In 2019, Cyprus launched its new National Healthcare System (NHS) as one of the major structural reforms required by bail-out agreement with International Monetary Fund, European Commission and Central Bank (known Troika) which averted bankruptcy in 2011. This paper presents key features NHS: A Health Insurance Fund operated Organisation pays for services provided a mix public private providers. prerequisite establishment this quasi-market was transfer hospitals from Ministry to State...
The continuing increase of pharmaceutical expenditure calls for new approaches to pricing and reimbursement pharmaceuticals. Value based pharmaceuticals is emerging as a useful tool possess theoretical attributes help health system cope with rising expenditure. To assess the feasibility introducing value-based scheme in Cyprus explore integrative framework. A probabilistic Markov chain Monte Carlo model was created simulate progression advanced renal cell cancer comparison sorafenib standard...
As part of a bailout agreement with the International Monetary Fund, European Commission and Central Bank (known as Troika), Cyprus had to achieve fiscal surplus through budget constraints efficiency enhancement. result, number policy changes were implemented, including reform healthcare sector, major reforms are planned for upcoming years, mainly via introduction National Health System. This paper presents provides an overview recent reforms, assesses recently implemented policies proposes...
Within the framework of burden disease (BoD) approach, and injury estimates attributable to risk factors are a useful guide for policy formulation priority setting in prevention. Considering important differences methods, their impact on estimates, we conducted scoping literature review to: (1) map BoD assessments including performed across Europe; (2) identify methodological choices comparative assessment (CRA) methods.We searched multiple databases, grey websites targeted public health...
This study aims to estimate the budget impact of luspatercept reimbursement as an adjuvant standard management β-thalassaemia major in Cyprus, from a societal perspective, and assess financial feasibility its inclusion armamentarium. A 5-year horizon model was developed determine reimbursing for Cyprus. Two treatment discontinuation scenarios were elaborated. In first scenario, is reimbursed complementary best supportive care, dropout rate 40% assumed based on published real-world data,...
The Oncology field is characterised by a steady increase in demand and consistent launching of innovative expensive products. Therefore, cost-effectiveness analysis can contribute as significant decision-making tool elucidating the most economically efficient ways to satisfy compelling health needs.The scope this study estimate axitinib versus sorafenib, for second-line treatment renal cell carcinoma. A literature review evidence synthesis was performed probabilistic Markov Model employed...
The pharmaceutical sector has been established as the primary cost driver in health. scope of this paper is to explore drivers expenditure Cyprus by decomposing sales and assessing impact prices, volumes substitution effect. We used a statistical approach decompose growth public during 2005–2011 into three elements: 1) effect; 2) price 3) increase consumption. further decomposed consumption into: prescription/visits; visits/beneficiaries; beneficiaries. Pharmaceutical grew 31.4 % volume...