Christiano Spindler

ORCID: 0000-0002-4901-656X
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About
Contact & Profiles
Research Areas
  • Birth, Development, and Health
  • Epigenetics and DNA Methylation
  • Stress Responses and Cortisol
  • Neonatal and fetal brain pathology
  • Histone Deacetylase Inhibitors Research
  • Infant Development and Preterm Care
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neuroendocrine regulation and behavior
  • Neurogenesis and neuroplasticity mechanisms
  • Anesthesia and Neurotoxicity Research
  • Adipose Tissue and Metabolism
  • Genetics and Neurodevelopmental Disorders
  • Carcinogens and Genotoxicity Assessment
  • Antioxidant Activity and Oxidative Stress
  • Circadian rhythm and melatonin
  • Identity, Memory, and Therapy
  • Vitamin C and Antioxidants Research
  • Cholinesterase and Neurodegenerative Diseases
  • Air Quality and Health Impacts
  • S100 Proteins and Annexins
  • High Altitude and Hypoxia
  • Spaceflight effects on biology
  • Child Welfare and Adoption
  • Metabolism and Genetic Disorders
  • Tryptophan and brain disorders

Universidade Federal do Rio Grande do Sul
2011-2021

Universidade Federal do Rio Grande
2021

Centro de Excelência em Bioinformática
2013

Hospital de Clínicas de Porto Alegre
2011-2012

Neonatal hypoxic-ischemic encephalopathy (HI) is a major cause of nervous system damage and neurological morbidity. Perinatal malnutrition affects morphological, biochemical behavioral aspects neural development, including pathophysiological cascades cell death triggered by ischemic events, so modifying resulting brain damage. Female Wistar rats were subjected to protein restriction during pregnancy lactation (control group: 25% soybean protein; malnourished 7%). Seven days after delivery...

10.1016/j.brainres.2011.12.024 article EN publisher-specific-oa Brain Research 2011-12-20

It is widely known that maternal physical exercise able to induce beneficial improvements in offspring cognition; however, the effects of paternal have not been explored detail. The present study was designed evaluate impact on memory and learning, neuroplasticity DNA methylation levels hippocampus male offspring. Adult Wistar rats were divided into two groups: sedentary or exercised fathers. preconception protocol consisted treadmill running, 20 minutes daily, 5 consecutive days per week...

10.4103/1673-5374.245473 article EN cc-by-nc-sa Neural Regeneration Research 2018-12-11
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