Thomas Cherian

ORCID: 0000-0002-4910-6880
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Retinal and Optic Conditions
  • Memory and Neural Mechanisms
  • Primate Behavior and Ecology
  • Face Recognition and Perception
  • Zebrafish Biomedical Research Applications
  • Visual perception and processing mechanisms
  • Retinal and Macular Surgery
  • Glaucoma and retinal disorders
  • Digital Imaging for Blood Diseases
  • Advanced Graph Neural Networks
  • Plant biochemistry and biosynthesis
  • Imbalanced Data Classification Techniques
  • Gaze Tracking and Assistive Technology
  • Corneal surgery and disorders
  • Plant Reproductive Biology
  • Philosophy and History of Science
  • Neural and Behavioral Psychology Studies
  • Plant and animal studies
  • Topic Modeling
  • Ocular Oncology and Treatments
  • Tactile and Sensory Interactions
  • Aortic Thrombus and Embolism
  • Data Visualization and Analytics

Indian Institute of Science Bangalore
2020-2025

Little Flower Hospital & Research Centre
2014-2023

Lakeshore Hospital
2014

University of Kerala
1981

Diabetic retinopathy (DR) is one of the most common retinal diseases that cause preventable blindness in diabetic patients. The timely screening and grading images minimize possibility vision loss. However, manual images, for detecting micro lesions early stages DR, time-consuming. This paper proposes an ensemble deep convolutional neural network (CNN) models accurate detection DR using fundus images. Each input image divided into four patches at first stage passed on to pre-trained CNN...

10.1016/j.jksuci.2021.05.009 article EN cc-by-nc-nd Journal of King Saud University - Computer and Information Sciences 2021-05-25

Diabetic retinopathy (DR) at risk of vision loss (referable DR) needs to be identified by retinal screening and referred an ophthalmologist. Existing automated algorithms have mostly been developed from images acquired with high cost mydriatic cameras cannot applied in the settings used most low- middle-income countries. In this prospective multicentre study, we a deep learning system (DLS) that detects referable DR using handheld non-mydriatic fundus camera non-technical field workers 20...

10.1038/s41598-023-28347-z article EN cc-by Scientific Reports 2023-01-25

National estimates of the prevalence vision impairment and blindness in people with diabetes are required to inform resource allocation. People more susceptible conditions such as diabetic retinopathy that can impair vision; however, these often missed national studies. This study aims determine risk factors India. Data from SMART-India study, a cross-sectional survey coverage 42 147 Indian adults aged 40 years older, collected using complex sampling design, were used obtain nationally...

10.1016/s2214-109x(24)00035-4 article EN cc-by The Lancet Global Health 2024-02-28

ABSTRACT Monkeys are widely used as model organisms for human vision and cognition. While their anatomy physiology strongly correspond to humans, it is unclear what extent perception matches with ours. Previous studies have evaluated specific aspects of perception, after extensive training on customized tasks that could altered perception. To resolve these issues, we trained monkeys perform an oddball visual search task natural images, tested them carefully controlled images detect a variety...

10.1101/2025.01.30.635614 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-01-31

Screening effectively identifies patients at risk of sight-threatening diabetic retinopathy (STDR) when retinal images are captured through dilated pupils. Pharmacological mydriasis is not logistically feasible in non-clinical, community DR screening, where acquiring gradable using handheld devices exhibits high technical failure rates, reducing STDR detection. Deep learning (DL) based gradability predictions acquisition could prompt device operators to recapture insufficient quality images,...

10.1038/s41598-021-89027-4 article EN cc-by Scientific Reports 2021-05-04

Macaque monkeys are widely used to study vision. In the traditional approach, brought into a lab perform visual tasks while they restrained obtain stable eye tracking and neural recordings. Here, we describe novel environment cognition in more natural setting as well other social behaviors. We designed naturalistic with an integrated touchscreen workstation that enables high-quality unrestrained monkeys. this train on challenging same-different task. also show can reveal interesting As proof...

10.7554/elife.63816 article EN cc-by eLife 2021-11-25

Diabetic retinopathy is one of the most common retinal diseases in diabetic patients, resulting avoidable blindness. Therefore, early detection and grading images are crucial to reduce risk vision loss. Also, DR an automated manner critical for effective care. The objective this study classify evaluate fundus into two levels. In current scenario, compared feature-based image classification techniques, convolutional neural networks have a higher efficiency. This work presents comparative...

10.1109/iccisc52257.2021.9484967 article EN 2021 International Conference on Communication, Control and Information Sciences (ICCISc) 2021-06-16

Language models, being at the heart of many NLP problems, are always great interest to researchers. Neural language models come with advantage distributed representations and long range contexts. With its particular dynamics that allow cycling information within network, `Recurrent neural network' (RNN) becomes an ideal paradigm for modeling. Long Short-Term Memory (LSTM) architecture solves inadequacies standard RNN in modeling long-range In spite a plethora variants, possibility add...

10.48550/arxiv.1811.06477 preprint EN other-oa arXiv (Cornell University) 2018-01-01

Diabetic retinopathy is an irreversible eye disease that a prominent cause of blindness globally. For proper diagnosis and vision protection, it essential to detect DR early accurately. In the current scenario challenging in automated manner using fundus images. This work investigates performance deep learning based CNN models effective classification. We explore three popular (Xception, InceptionV3, ResNet50) for categorization this retinal disease. A comparative study pre-trained are...

10.1109/iceeict53079.2022.9768480 article EN 2022 First International Conference on Electrical, Electronics, Information and Communication Technologies (ICEEICT) 2022-02-16

Abstract A case of malignant pleomorphic adenoma the left parotid gland which metastasized to kidney and multiple subcutaneous sites is presented. The patient presented as an acute emergency due spontaneous rupture containing metastasis. All distant metastatic lesions were confined right side body.

10.1017/s0022215100120444 article EN The Journal of Laryngology & Otology 1992-07-01

ABSTRACT Macaque monkeys are widely used to study the neural basis of cognition. In traditional approach, monkey is brought into a lab perform tasks while it restrained obtain stable gaze tracking and recordings. This unnatural setting prevents studying brain activity during natural, social complex behaviors. Here, we designed naturalistic environment with an integrated behavioral workstation that enables task training viable in freely moving monkeys. We this facility train on challenging...

10.1101/2020.09.25.311555 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-09-28

To report the case of a 52-year-old female with recent complaint decreased vision associated well-defined depigmented lesion in macula right eye. She had history surgery for pituitary microadenoma and breast lump excision. Based on spectral-domain optical coherence tomography, fundus fluorescein angiography, indocyanine green B-scan ultrasonography, diagnosis eye choroidal osteoma was made. Subretinal fluid (SRF) noted absence obvious classic neovascularization (CNV). The patient given...

10.4103/kjo.kjo_79_17 article EN cc-by-nc-sa Kerala Journal of Ophthalmology 2017-01-01

Cytological investigations on Camellia sinensis, C. assamica, and their hybrid (Jat) were undertaken in the present study.The somatic chromosome number (2n=30) observed species sinensis assamica is conformity with earlier reports. Also meiosis pollen mother cells was regular these species. However irregular China-Assam hybrid. Localized unpairing at pachytene, stickiness resulting apparent higher association, laggards, sticky bridges etc. variations of daughter nuclei telophase II...

10.1508/cytologia.46.767 article EN CYTOLOGIA 1981-01-01

Cholesterol embolism is a rare complication of percutaneous vascular procedures. It usually diagnosed from the typical cutaneous manifestations and delayed development renal failure. Here we report patient who developed incessant vomiting following procedure later cholesterol embolism. Even though gastrointestinal may be seen up to 20% patients, this first case in which symptoms are as initial presentation

10.1016/j.jicc.2014.09.002 article EN Journal of Indian College of Cardiology 2014-10-04

10.1093/ajcp/142.suppl1.211 article EN American Journal of Clinical Pathology 2014-10-01

10.4103/ijo.ijo_1196_21 article IT Indian Journal of Ophthalmology - Case Reports 2022-04-01

When a spiky object is occluded, we have no trouble believing that the hidden portions are also spiky. Whether this process occurs automatically in perception, or requires cognitive reasoning unclear. Here, devised novel “free-choice” paradigm to reveal what monkeys see behind an occluded display. On 80% of trials, denoted as unambiguous two items (sample and test) were shown with intervening delay, trained make “same” “different” response. These trials consisted unoccluded displays...

10.1167/jov.22.14.3451 article EN cc-by-nc-nd Journal of Vision 2022-12-05

When a spiky object is occluded, we have the compelling percept that its features continue behind occluder. Although many real-world objects contain complex features, it unclear how their are amodally completed and whether this process automatic. To end, asked participants to search for oddball targets among distractors similarity relations in visual between occluded displays match better with global or local completions of these displays. In Experiment 1, when curved/straight corners were...

10.31234/osf.io/m43vq preprint EN 2021-07-03

We can easily recognize objects even when they are occluded. Does our perception complete the occluded edges linearly or it also employ more sophisticated extrapolation? To investigate this, we created displays where each shape had two possible completions. These identical contours in unoccluded portion but differed portion, such that one appeared to be likely behind occluder, and other was unlikely. Across sets of displays, manipulated either curvature edge (‘curvature’ set) numerosity...

10.1167/jov.21.9.2291 article EN cc-by-nc-nd Journal of Vision 2021-09-01

10.4103/ijo.ijo_2861_20 article EN Indian Journal of Ophthalmology - Case Reports 2021-10-01
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