A5045215649- Protein Hydrolysis and Bioactive Peptides
- Proteins in Food Systems
- Bee Products Chemical Analysis
- Phytochemicals and Antioxidant Activities
- Blood properties and coagulation
- Tendon Structure and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Advanced Glycation End Products research
- Pesticide Exposure and Toxicity
- Stress Responses and Cortisol
- Animal Diversity and Health Studies
- Cardiac Fibrosis and Remodeling
- Atrial Fibrillation Management and Outcomes
- Health and Well-being Studies
- Phytase and its Applications
- Sleep and Work-Related Fatigue
- S100 Proteins and Annexins
- IL-33, ST2, and ILC Pathways
- Hormonal and reproductive studies
- Liver physiology and pathology
- Microbial metabolism and enzyme function
- Biochemical Acid Research Studies
- Pharmacological Effects of Natural Compounds
- Pharmacology and Obesity Treatment
Jordan University of Science and Technology
2020-2025
Montreal Heart Institute
2017-2025
Université de Montréal
2017-2019
Nigella sativa is one of the nutraceuticals that has gained popularity and studied extensively in recent decades as it considered a safe medicinal plant for use dietary supplement. N. contains wide variety bioactive substances, which include polyphenols, volatile oils (thymoquinone p-cymene), proteins, peptides. The biological attributes antioxidant, antimicrobial, antifungal, anti-inflammatory, anticancer, antidiabetic, antihypertensive, hypolipidemic, antioxidant activities, have potential...
Atrial fibrillation (AF) is the most common cardiac arrhythmia. AF can lead to severe complications, including stroke, myocardial infarction, and sudden death. risk factors include pathological aging conditions such as obesity, diabetes, hypertension. Clinical data revealed that cardiothoracic non-cardiothoracic surgeries are also important for AF. Post-operative (POAF) associated with public health costs caused by increased hospitalization, frequent emergency room visits, enhanced...
Abstract Aims Recent studies suggest that bioactive mediators called resolvins promote an active resolution of inflammation. Inflammatory signalling is involved in the development substrate for atrial fibrillation (AF). The aim this study to evaluate effects resolvin-D1 on arrhythmogenic remodelling resulting from left ventricular (LV) dysfunction induced by myocardial infarction (MI) rats. Methods and results MI was produced anterior descending coronary artery ligation. Intervention groups...
Sleep disorders are extremely prevalent in the general population. College students more susceptible to sleep problems. This is due increased competition getting a job position and current alterations labor market. Poor has deleterious effects on college students, but its frequency among not been documented Jordan. So, aims of this study assess prevalence daytime sleepiness medical Jordan look for any links between academic performance. A cross-sectional performed paramedical specialties...
Transglutaminase (TG) isoforms control diverse normal and pathophysiologic processes through their capacity to cross-link extracellular matrix (ECM) proteins. Their functional signalling roles in cardiac fibrosis remain poorly understood, despite some evidence of TG2 involvement abnormal ECM remodelling heart diseases. In this study, we investigated the role TG1 mediating fibrotic signalling, collagen cross-linking, cell proliferation healthy fibroblasts by siRNA-mediated knockdown. siRNA...
Abstract This study aimed to assess the biological properties of peptide fractions isolated from dried fermented dairy products (jameed) as influenced by processing. Peptide were separated reversed‐phase high‐performance liquid chromatography (RP‐HPLC) salted (Sa) and unsalted (Us) cow milk jameed after drying curd sun (Sd) or freeze‐drying (Fd) characterized for their antioxidant capacity inhibitory activity toward angiotensin I‐converting enzyme (ACE) α‐amylase. Sd samples showed more...
Androgenic–anabolic steroids (AASs) are synthetic derivative forms of the hormone testosterone. Sustanon® 250 solution for injection is one those AASs that used low levels and self-administered recreational purposes. This study was conducted to investigate effects sustanon on body weight male female rats. Animals were injected different doses (vehicle, 1, 3.2, 10, 32 100 mg/kg, I.M., once/week, 6 weeks), weights each animal obtained. The rats observed agitated/aggressive behaviours every...
This research aimed to determine the biofunctional properties of wheat flour (WF) protein fractions and modifications antioxidant, anti-α-amylase anti-angiotensin-I converting enzyme (ACE) activities induced by action digestive endopeptidases in vitro. A molecular characterization most abundant fractions, i.e., albumins, glutelins-1, glutelins-2 prolamins, showed that low- high-MW polypeptides rich cysteine, glutamic acid leucine were present albumins glutelins, whereas low-MW subunits with...
Psychosocial stress, a common feature in modern societies, impairs cognitive functions. It is suggested that stress hormones and elevated excitatory amino acids during are responsible for stress-induced deficits. Reduced brain-derived neurotrophic factor (BDNF) levels, increased oxidative alteration of synaptic plasticity biomarkers also possible contributors to the negative impact on learning memory. Sildenafil citrate selective phosphodiesterase type 5 (PDE5) inhibitor first oral therapy...
The aim of this study was to determine the phenolic and protein contents differently prepared co-precipitates (Co) from flaxseed soybean antioxidant activity inhibitory towards angiotensin-1-converting enzyme (ACE) their constituents. Protein were by alkaline extraction involving mixing (F) (S) powders (Mp) or extracts (Me), followed isoelectric (Ie) precipitation Ie heating (Ie-He). highest yields obtained with Co-Me/Ie (53.28% 25.58%, respectively) Co-Me/Ie-He (46.84% 19.87%), which also...
This study was carried out to investigate the biological properties of bioactive peptides derived from digestive enzymatic hydrolysis for nanoscaled protein particles camel whey proteins. The hydrolysates were tested aromatic content, antioxidant activity, α‐amylase inhibitory and angiotensin‐converting enzyme (ACE) activities. sonicated showed sizes less than 100 nm distributed in a 75% volume with relatively stable −23.1 mV zeta potential value. Sonication enhanced total ring content...
Royal jelly (RJ) is a multifunctional bee product with unique composition and wide-ranging biological properties, including antioxidant, anti-inflammatory antiproliferative activities. Still, little known about the possible myocardial protective properties of RJ. Considering that sonication could enhance RJ bioactivity, this study aimed to assess effects non-sonicated (NS) sonicated (S) on fibrotic signaling, cell proliferation, collagen production in cardiac fibroblasts. S-RJ was produced...