A5040688854- Advanced Drug Delivery Systems
- Antimicrobial Peptides and Activities
- Nanoparticle-Based Drug Delivery
- Advancements in Transdermal Drug Delivery
- Lipid Membrane Structure and Behavior
- RNA Interference and Gene Delivery
- Antimicrobial agents and applications
- Drug Solubulity and Delivery Systems
- Dendrimers and Hyperbranched Polymers
- Nanoplatforms for cancer theranostics
- HIV/AIDS drug development and treatment
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Advanced Polymer Synthesis and Characterization
- Antibiotics Pharmacokinetics and Efficacy
- HIV Research and Treatment
- Essential Oils and Antimicrobial Activity
- Hydrogels: synthesis, properties, applications
- Inhalation and Respiratory Drug Delivery
- Oral microbiology and periodontitis research
- Bacteriophages and microbial interactions
- Diabetes and associated disorders
- Chemical Synthesis and Analysis
- Immune Response and Inflammation
- Analytical Methods in Pharmaceuticals
University of KwaZulu-Natal
2016-2025
Alliant International University
2020
United States International University Africa
2020
Royal Gwent Hospital
2020
University of Florida
2011
University of Nottingham
1999-2001
Abstract To tackle the problems caused by bacterial biofilms, herein, this study reports an antimicrobial hybrid amphiphile (aHA) via dynamic covalent bonds for eradicating staphylococcal biofilms. aHA is synthesized iminoboronate ester formation between DETA NONOate (nitric oxide donor), 3 4‐dihydroxybenaldehyde, and phenylboronic acid‐modified ciprofloxacin (Cip). can self‐assemble in aqueous solution with ultra‐small critical aggregation concentration of 3.80 × 10 –5 m high drug loading...
Abstract Surface functionalization of nanoparticles has shown potential in enhancing the efficacy antibiotic-loaded nanosystems against drug-resistant bacteria. The objective this study was to synthesize and characterize an acid-cleavable pH-responsive polymer from methoxy polyethylene glycol oleylamine (mPEG-OA) surface modify vancomycin (VCM)-loaded niosomes evaluate their antibacterial anti-biofilm effectiveness methicillin-resistant Staphylococcus aureus (MRSA). novel mPEG-OA-coated were...
Abstract Introduction The application of biomimetic and stimuli-responsive nanocarriers displays considerable promise in improving the management bacterial sepsis overcoming antimicrobial resistance. Therefore, study aimed to synthesize a novel hyaluronic acid-lysine conjugate (HA-Lys) utilize attributes synthesized HA-Lys with Tocopherol succinate (TS) Oleylamine (OLA) formulation multifunctional pH-responsive HNLCs loaded vancomycin (VCM-HNLCs), combat sepsis. Methods A was characterized...