A5086385336- Phytochemicals and Antioxidant Activities
- Pomegranate: compositions and health benefits
- Essential Oils and Antimicrobial Activity
- Spectroscopy and Chemometric Analyses
- Fermentation and Sensory Analysis
- Meat and Animal Product Quality
- Protein Hydrolysis and Bioactive Peptides
- Antioxidant Activity and Oxidative Stress
- Tea Polyphenols and Effects
- Consumer Attitudes and Food Labeling
- Collagen: Extraction and Characterization
- Horticultural and Viticultural Research
- Bioactive Compounds in Plants
- Plant Pathogens and Fungal Diseases
- Dendrimers and Hyperbranched Polymers
- Tannin, Tannase and Anticancer Activities
- Heavy Metals in Plants
- Toxic Organic Pollutants Impact
- Cholinesterase and Neurodegenerative Diseases
- Seed and Plant Biochemistry
- RNA Interference and Gene Delivery
- Postharvest Quality and Shelf Life Management
- African Botany and Ecology Studies
- Plant tissue culture and regeneration
- Advanced Chemical Sensor Technologies
University of Genoa
2016-2025
Istituto Nazionale di Fisica Nucleare, Sezione di Genova
2019
Human neuroblastoma (NB), a pediatric tumor inclined to relapse, after an initial response therapy, usually develops resistance. Since several chemotherapeutics exert anticancer effect by increasing reactive oxygen species (ROS), NB cells overproduce antioxidant compounds becoming drugs-resistant. A strategy sensitize chemotherapy involves reducing their defenses and inducing ROS overproduction. Concerning this, although affected issues that limit clinical application,...
The aim of this study was to investigate the potential retrieving polyphenolic antioxidants directly from wet pomegranate marcs: fresh by-products obtained after juice processing. These mainly consist internal membranes (endocarp) and aril residues. Even if they are still edible, usually discharged during production and, thus, represent a great challenge in an eco-sustainable industrial context. Green technologies, such as ultrasound assisted extraction (UAE) microwave (MAE), have been...
Ellagic acid, a polyphenolic compound present in fruit and berries, has recently been the object of extensive research for its antioxidant activity, which might be useful prevention treatment cancer, cardiovascular pathologies, neurodegenerative disorders. Its protective role justifies numerous attempts to include it functional food preparations dietary supplements, not only limit unpleasant collateral effects chemotherapy. However, ellagic acid use as chemopreventive agent debated because...
Innovative antioxidant ellagic acid (EA) formulations suitable for oral and parenteral EA administration were achieved avoiding the use of harmful additives.
The aim of the study is to evaluate anti-tyrosinase activity different aqueous extracts obtained from pomegranate juice processing by-products. External peels two certified cultivars (Akko and Wonderful), were extracted using only water as extraction solvent. A traditional decoction a pulsed ultrasound-assisted (PUAE), both 10 min long, performed compared. All proved be rich in bioactive compounds. In particular, total phenolic content (TPC) ranged 148 237 mg gallic acid equivalent (GAE)/g...
FINNOVER is an EU Interreg-Alcotra project that aims to bring new perspectives floriculture enterprises by recovering useful bioproducts from the waste produced during processing of several aromatic species. In this study, a operation strategy recover lavender (Lavandula angustifolia Mill.) solid by-products remaining after extraction essential oil was developed. Pulsed ultrasound-assisted employed as sustainable and eco-compatible technology extract, in very short time (10 min),...
Children affected by chronic liver disease exhibit impaired neurocognitive development and growth due to the low absorption digestion of nutrients. Furthermore, malnutrition is an adverse prognostic factor in transplantation as it associated with increase morbidity mortality. D-α-tocopheryl-polyethylene-glycol-succinate (TPGS) currently administered per os a vitamin E source improve children’s survival well-being; however, TPGS alone does not reverse spinocerebellar degeneration lipid...
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Oryza sativa L. 'Violet Nori' is an Italian cultivar of spontaneous growing aromatic purple rice which particularly rich in polyphenolic compounds, especially anthocyanins, conferring it excellent antioxidant capacity. The present study aimed at increasing the extraction yields its compounds with green strategies and divided into two steps. first step concerned a solubility targeted polyphenols different ethanol:water mixtures by means theoretical prediction method, using simulation program...
The use of herbal food supplements, as a concentrate form vegetable extracts, increased so much over the past years to count them among relevant sources dietetic polyphenols. Bud-derivatives are category botanicals perceived "new entry" in this sector since they still poorly studied. Due lack manufacturing process specification, very different products can be found on market terms their polyphenolic profile depending experimental conditions manufacturing. In research two processes, using...
In this research, for the first time, an alternative method to produce Ribes nigrum bud derivatives is presented. Pulsed ultrasound-assisted extraction (PUAE), using a food-grade solvent according green chemistry principles, has been employed and compared conventional method. Traditionally, derivatives, category of botanicals marketed as plant food supplements in European Community, are produced by macerating meristematic tissues trees plants mainly spontaneously collected. Buds challenging...
Natural polyphenols such as Gallic Acid (GA) form an important class of bioactive chemical entities that, having innumerable biological properties, could represent a safer alternative to common drugs against several disorders, including platelet aggregation, radical oxygen species (ROS) hyperproduction, oxidative stress (OS) and bacterial infections. Unfortunately, their clinical uses are limited by pharmacokinetics drawbacks high sensitivity environmental factors. In order overcome these...
'Violet Nori' is a new spontaneous growing violet rice variety showing peculiar color in its fresh leaves as well. In this paper, the antioxidant properties and content of total phenols, radical scavengers, anthocyanins caryopses, flour, are explored compared. Ultrasonic-Assisted Extraction (UAE) employed for extraction phenolic compounds, improving conditions by Design Experiments (DoE). The obtained results show that Radical Scavenging Activities (RSAs), Total Phenolic Contents (TPCs),...
Ellagic acid, a polyphenolic compound present in fruits and berries, has recently been object of extensive research for its antioxidant activity, which might be useful the prevention treatment cancer, cardiovascular pathologies, neurodegenerative disorders. Its protective role justifies numerous attempts to include it functional food preparations dietary supplements not only limit unpleasant collateral effects chemotherapy. However, ellagic acid use as chemopreventive agent debated because...
Chestnut processing has increasingly grown in recent years. All the processes involved chestnut supply chain are characterized by production of high levels by-products that cause several environmental and disposal issues. The Castanea spp. fruit is related to a number episperm. This underutilized agricultural by-product may be evaluated as good resource for extraction health-promoting natural molecules, such phenolics. preliminary study aimed develop optimize, using multivariate statistical...