A5024743230- Advanced biosensing and bioanalysis techniques
- Multi-Criteria Decision Making
- Biosensors and Analytical Detection
- Rough Sets and Fuzzy Logic
- Transportation Planning and Optimization
- Human Mobility and Location-Based Analysis
- Photonic and Optical Devices
- Conducting polymers and applications
- Electrochemical sensors and biosensors
- ZnO doping and properties
- Magnetic properties of thin films
- Advanced Fiber Optic Sensors
- Educational Reforms and Innovations
- DNA and Nucleic Acid Chemistry
- Fuzzy Systems and Optimization
- RNA Interference and Gene Delivery
- Epigenetics and DNA Methylation
- Evacuation and Crowd Dynamics
- Advanced Biosensing Techniques and Applications
- Molecular Junctions and Nanostructures
- CRISPR and Genetic Engineering
- Urban Transport and Accessibility
- Gold and Silver Nanoparticles Synthesis and Applications
- Anodic Oxide Films and Nanostructures
- Analytical Chemistry and Sensors
Fudan University
2025
Chongqing University
2008-2022
Southwest University
2011-2021
Singapore Science Park
2007-2008
Institute of Microelectronics
2007-2008
Agency for Science, Technology and Research
2008
Arrays of highly ordered n-type silicon nanowires (SiNW) are fabricated using complementary metal-oxide semiconductor (CMOS) compatible technology, and their applications in biosensors investigated. Peptide nucleic acid (PNA) capture probe-functionalized SiNW arrays show a concentration-dependent resistance change upon hybridization to target DNA that is linear over large dynamic range with detection limit 10 fM. As other biosensing devices, the sensing mechanism can be understood terms...
The development of a sensing platform with high sensitivity and specificity, especially programmability universal applicability, for the detection clinically relevant molecules is highly valuable disease monitoring confirmation but remains challenge. Here, first time, we introduce clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system into an immobilization-free electrochemical biosensing sensitively specifically detecting disease-related nucleic acids small molecules....
A nanogapped microelectrode-based biosensor array is fabricated for ultrasensitive electrical detection of microRNAs (miRNAs). After peptide nucleic acid (PNA) capture probes were immobilized in nanogaps a pair interdigitated microelectrodes and hybridization was performed with their complementary target miRNA, the deposition conducting polymer nanowires, polyaniline (PAn) carried out by an enzymatically catalyzed method, where electrostatic interaction between anionic phosphate groups miRNA...
Robustness is one of the most important performance criteria for any rail transit network (RTN), because it helps us enhance efficiency RTN. Several studies have addressed issue RTN robustness primarily from perspectives given structures or static distributions passenger flow. An open problem that remains in fully understanding how to take spatio-temporal characteristics travel into consideration, since dynamic flow an can readily trigger unexpected cascading failures. This paper addresses...
Exploring novel systems with perpendicular magnetic anisotropy (PMA) is vital for advancing memory devices. In this study, we report an intriguing PMA system involving ultrathin Fe layer on antiferromagnetic (AFM) CoO(001) surface. The measured field inversely proportional to the thickness, indicating interfacial origin of PMA. Temperature-dependent measurements reveal that antiferromagnetism CoO has a negligible effect By leveraging magneto-optic Kerr and birefringence effect, achieve...
Sequence-specific DNA detection is a routine job in medical diagnostics and genetic screening. Alternative to fluorescence readout scheme or electrophoresis approach, various kinds of rapid, low-cost, facile, label-free methods have also been developed last decades. Among these, direct electrical received increasing attention but more research desirable. Particularly, enhancement with high discrimination must be employed selectively amplify the responding signal. A chip-based biosensor was...
The robustness is a crucial and essential problem of subway network (SN), which can help us improve the efficiency transportation system. Several existing researches have analyzed SN based on rail structure or static distribution passenger flow. However, spatiotemporal characteristic flow also plays an important role in robustness, since it trigger some unexpected cascading failures SN. Therefore, how to characterize effect this failure still remains open problem. In paper, we address above...
Exploring novel systems with perpendicular magnetic anisotropy (PMA) is vital for advancing memory devices. In this study, we report an intriguing PMA system involving ultrathin Fe layer on antiferromagnetic (AFM) CoO(001) surface. The measured field inversely proportional to the thickness, indicating interfacial origin of PMA. Temperature-dependent measurements reveal that antiferromagnetism CoO has a negligible effect By leveraging magneto-optical Kerr and birefringence effect, achieved...
Abstract We propose and investigate a phase‐shifted long‐period fiber grating (LPFG) written by CO 2 laser in twisted single‐mode fibers (SMFs).For the beating effect, two peaks of LPFG derived from phase‐shift further split into peaks, respectively. The evolution characterization transmission spectra were investigated. channel spacing LPFGs Er‐doped could be much narrower than that which normal SMF. Polarization dependent loss beat‐gratings is less 0.6 dB. This type gratings provides...
We report here a biosensor for the direct electrical detection of nucleic acids by forming conductive paths with zirconium-activated indium tin oxide (ITO) nanoparticle tags in gaps pair interdigitated electrodes. The formation ITO networks bridges electrode pair, allowing at subpicomolar levels high specificity. acid described is rapid, ultrasensitive, and able to directly detect without involving biological ligation, second probe, or amplification. It particular importance development gene...
Spatial-frequency division multiplexing (SFDM)/coarse-wavelength (CWDM) of in-line fiber-optic etalon (ILFE) strain sensors, formed by a section hollow-core photonic crystal fiber (HCPCF), is reported in this paper, for the first time to best our knowledge. Due low thermal expansion coefficient HCPCF, such sensor much less sensitive temperature change compared with conventional ILFE sensors. In meanwhile, as transmission loss HCPCF very low, cavity length can be longer than existing ILFEs,...
A nanogapped microelectrode-based biosensor array is fabricated for ultrasensitive electrical detection of nucleic acids. After immobilizing peptide acid (PNA) capture probes in nanogaps a pair interdigitated microelectrodes and performing hybridization with their complementary target acids, the deposition conducting polymer, polyaniline (PAn) nanowires, carried out by an enzymatically catalyzed method, where electrostatic interaction between anionic phosphate groups acids cationic aniline...