A5084062088- Heart Failure Treatment and Management
- Cardiovascular and exercise physiology
- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Organ Transplantation Techniques and Outcomes
- Muscle activation and electromyography studies
- Viral Infections and Immunology Research
- Cardiac pacing and defibrillation studies
- Thyroid Disorders and Treatments
- Fuel Cells and Related Materials
- Renal Transplantation Outcomes and Treatments
- Healthcare Policy and Management
- Congenital Heart Disease Studies
- Chronic Disease Management Strategies
- Thyroid Cancer Diagnosis and Treatment
- Potassium and Related Disorders
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Frailty in Older Adults
Saint Thomas Health
2019-2021
St. Thomas Hospital
2019
St Thomas' Hospital
2019
Saint Thomas West Hospital
2015
Vanderbilt University Medical Center
1996-2005
Nashville VA Medical Center
2005
Vanderbilt University
1999-2004
Ochsner Medical Center
2000
University of Iowa Hospitals and Clinics
2000
University of Pennsylvania
1997
In two interim analyses of this trial, patients with advanced heart failure who were treated a fully magnetically levitated centrifugal-flow left ventricular assist device less likely to have pump thrombosis or nondisabling stroke than mechanical-bearing axial-flow device.We randomly assigned receive either the irrespective intended goal use (bridge transplantation destination therapy). The composite primary end point was survival at 2 years free disabling reoperation replace remove...
Background Most patients with heart failure are currently managed by physicians little specific expertise in failure. This management system has been associated evidence of suboptimal care, such as high rates hospital readmission and underuse ACE inhibitors. The current study was undertaken to determine whether hospitalization functional outcomes improved when special working a dedicated program. Methods Results All referred the Vanderbilt Heart Failure Transplantation Program between July...
Peak exercise oxygen consumption (Vo2), a noninvasive index of peak cardiac output (CO), is widely used to select candidates for heart transplantation. However, Vo2 can be influenced by noncardiac factors such as deconditioning, motivation, or body composition and may yield misleading prognostic information. Direct measurement the CO response avoid this problem more accurately predict prognosis.Hemodynamic ventilatory responses maximal treadmill were measured in 185 ambulatory patients with...
Background In patients with heart failure, excessive sympathetic activation during exercise could interfere performance by impairing arteriolar dilation in working muscle and adversely altering skeletal metabolic behavior. To test this hypothesis, we examined the effect of sympathoinhibition clonidine, a central sympatholytic agent, on blood flow metabolism failure. Methods Results Swan-Ganz femoral venous catheters were inserted 20 chronic failure intolerance (peak V̇ o 2 =9.3±1.4 [SEM]...
Lang, Chim C., Don B. Chomsky, Glenn Rayos, T. K. Yeoh, and John R. Wilson. Skeletal muscle mass exercise performance in stable ambulatory patients with heart failure. J. Appl. Physiol. 82(1): 257–261, 1997.—The purpose of this study was to determine whether skeletal atrophy limits the maximal capacity Body composition were measured 100 assessed by using dual-energy X-ray absorption. Peak oxygen consumption (V˙o 2 peak ) anaerobic threshold a Naughton treadmill protocol Medical Graphics...
Heart failure disproportionately affects Black patients. Whether differences among race influence outcomes in advanced heart with use of a fully magnetically levitated continuous-flow left ventricular assist device remains uncertain. We included 515 IDE (Investigational Device Exemption) clinical trial patients and 500 Continued Access Protocol implanted the HeartMate 3 MOMENTUM study (Multicenter Study MagLev Technology Patients Undergoing Mechanical Circulatory Support Therapy With 3)....
Lang, Chim C., Don B. Chomsky, Javed Butler, Shiv Kapoor, and John R. Wilson. Prostaglandin production contributes to exercise-induced vasodilation in heart failure. J. Appl. Physiol. 83(6): 1933–1940, 1997.—Endothelial release of prostaglandins may contribute skeletal muscle arteriolar patients with To test this hypothesis, we examined the effect indomethacin on leg circulation metabolism eight chronic failure patients, aged 55 ± 4 yr. Central hemodynamics blood flow, determined by...
Electronic home monitoring for chronic heart failure is emerging as an available option to add our armamentarium a vital part of the multidisciplinary care process. This investigation describes early clinical results multicenter study that suggests important trends in medical resource utilization may be attained by use this modality. (c)2000 CHF, Inc.