A5049563849- Particle physics theoretical and experimental studies
- Nuclear physics research studies
- Lymphoma Diagnosis and Treatment
- Nuclear Physics and Applications
- Quantum Chromodynamics and Particle Interactions
- Atomic and Subatomic Physics Research
- Particle Detector Development and Performance
- Dark Matter and Cosmic Phenomena
- High-Energy Particle Collisions Research
- Ubiquitin and proteasome pathways
- Advanced NMR Techniques and Applications
- Chronic Lymphocytic Leukemia Research
- Particle accelerators and beam dynamics
- X-ray Spectroscopy and Fluorescence Analysis
- Particle Accelerators and Free-Electron Lasers
- Quantum, superfluid, helium dynamics
- Catalysis and Hydrodesulfurization Studies
- Radiation Detection and Scintillator Technologies
- Electron and X-Ray Spectroscopy Techniques
- Multiple Myeloma Research and Treatments
- Radiation Therapy and Dosimetry
- Monoclonal and Polyclonal Antibodies Research
- Atomic and Molecular Physics
- CAR-T cell therapy research
- Muon and positron interactions and applications
Military University Hospital Prague
2024
University Hospital Kralovske Vinohrady
2021-2024
Charles University
2008-2024
University of Alberta
2002-2023
University of Cagliari
2023
Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Gran Sasso
2023
University of California, Riverside
2023
Princeton University
2023
University Hospital in Motol
2008-2019
University of Pardubice
2010-2011
DEAP-3600 is a single-phase liquid argon (LAr) direct-detection dark matter experiment, operating 2 km underground at SNOLAB (Sudbury, Canada). The detector consists of 3279 kg LAr contained in spherical acrylic vessel. This paper reports on the analysis $758\text{ }\text{ }\mathrm{tonne}\ifmmode\cdot\else\textperiodcentered\fi{}\mathrm{day}$ exposure taken over period 231 live-days during first year operation. No candidate signal events are observed WIMP-search region interest, which...
This Letter reports the first results of a direct dark matter search with DEAP-3600 single-phase liquid argon (LAr) detector. The experiment was performed 2 km underground at SNOLAB (Sudbury, Canada) utilizing large target mass, LAr contained in spherical acrylic vessel 3600 kg capacity. is viewed by an array PMTs, which would register scintillation light produced rare nuclear recoil signals induced particle scattering. An analysis 4.44 live days (fiducial exposure 9.87 ton day) data taken...
To investigate the roles of BCL2, MCL1, and BCL-XL in survival diffuse large B-cell lymphoma (DLBCL).Immunohistochemical analysis 105 primary DLBCL samples, Western blot 18 cell lines for expression BCL-XL. Pharmacologic targeting with ABT-199, homoharringtonine (HHT), ABT-737. Analysis clones manipulated expressions Immunoprecipitation MCL1 complexes selected lines. Experimental therapy aimed at inhibition BCL2 using ABT-199 HHT, single agent, or combination, vitro vivo on cell-based murine...
Abstract Purpose: Mantle cell lymphoma (MCL) is an aggressive subtype of B-cell non-Hodgkin lymphomas characterized by (over)expression BCL2. A BCL2-targeting drug, venetoclax, has promising anticancer activity in MCL. We analyzed molecular mechanisms venetoclax resistance MCL cells and tested strategies to overcome it. Experimental Design: confirmed key roles proapoptotic proteins BIM NOXA mediating venetoclax-induced death Both are, however, differentially expressed lines compared with...
The tensor polarization t20 of the recoil deuteron in elastic e-d scattering has been measured for three values four-momentum transfer, q=3.78, 4.22, and 4.62 fm−1. data have used to locate first node charge monopole form factor at q=4.39±0.16 results are reasonable agreement with expectations based on nucleon-meson description nuclear dynamics.Received 28 May 1991DOI:https://doi.org/10.1103/PhysRevLett.67.173©1991 American Physical Society
The first elastic-scattering analyzing-power (${A}_{y}$) data at 0.8 GeV are presented and discussed. Angular distributions of ${A}_{y}$ over the range 2\ifmmode^\circ\else\textdegree\fi{} to 20\ifmmode^\circ\else\textdegree\fi{} (30\ifmmode^\circ\else\textdegree\fi{} for $^{12}\mathrm{C}$) have been obtained $^{12}\mathrm{C}$, $^{58}\mathrm{Ni}$, $^{90}\mathrm{Zr}$, $^{208}\mathrm{Pb}$ using high-resolution spectrometer Clinton P. Anderson Meson Physics Facility. analyzing powers oscillate...
Abstract The knowledge of scintillation quenching $$\alpha $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mi>α</mml:mi> </mml:math> -particles plays a paramount role in understanding -induced backgrounds and improving the sensitivity liquid argon-based direct detection dark matter experiments. We performed relative measurement MeV energy region using radioactive isotopes ( $$^{222}$$ <mml:mmultiscripts> <mml:mrow/> <mml:mn>222</mml:mn> </mml:mmultiscripts> Rn, $$^{218}$$...
An experiment resulting in the first measurement of isospin-mixing, charge-symmetry-violating component $n\ensuremath{-}p$ interaction has been performed. The determined difference angles zero crossing neutron and proton analyzing powers ${A}_{n}$ ${A}_{p}$ at 477 MeV. In terms laboratory scattering angle neutron, measured is ${\ensuremath{\theta}}_{0n}({A}_{n})\ensuremath{-}{\ensuremath{\theta}}_{0n}({A}_{p})=+0.13\ifmmode^\circ\else\textdegree\fi{}...
The authors propose three phenomenological models for wideband electromagnetic induction (EMI) response of buried conductors, such as unexploded ordnance (UXO) or metal parts in landmines. are based on analytic solutions spheres, cylinders, and wire loops, produce physically reasonable predictions a variety targets at all frequencies interest including matches to theory the low- high-frequency limits. All excellent fits test data run quickly enough be practical use inversion schemes. present...
The tensor polarization of the recoil deuteron in elastic electron-deuteron scattering has been measured at Bates Linear Accelerator Center three values four-momentum transfer Q=3.78, 4.22, and 4.62 fm−1, corresponding to incident electron energies 653, 755, 853 MeV. scattered electrons deuterons were detected coincidence. transported a liquid hydrogen target undergo second scattering. angular distribution d→-p was using polarimeter. polarimeter calibrated an auxiliary experiment polarized...
A proton-proton bremsstrahlung experiment has been carried out at TRIUMF using a 280-MeV polarized proton beam impinging on liquid-hydrogen target. All three outgoing particles were detected: the higher-energy in magnetic spectrometer, lower-energy with plastic scintillators, and photon lead-glass Cherenkov detectors. The shows first unambiguous evidence for off-shell effects free nucleon-nucleon interaction, that analyzing powers disagree strongly predictions of soft-photon approximation...
The effect of isospin-violating, charge-symmetry-breaking (CSB) terms in the np interaction has been observed at TRIUMF by measuring difference zero-crossing angles neutron and proton analyzing powers, ${A}_{n}$ ${A}_{p}$, a energy 477 MeV. scattering asymmetries were measured with beam incident on polarizable target. To reduce systematic errors, interleaved measurements ${A}_{p}$ made using same target (apart from their respective polarization states). Neutrons protons detected coincidence...
The parity-violating longitudinal analyzing power, Az, has been measured in pp elastic scattering at an incident proton energy of 221 MeV. result obtained is Az =(0.84 +/- 0.29 (stat.) 0.17 (syst.)) x 10^{-7}. This experiment unique that it selects a single parity violating transition amplitude, 3P2-1D2, and consequently directly constrains the weak meson-nucleon coupling constant h^pp_rho When this taken together with existing violation data, constants h^pp_omega can, for first time, both...
TRIUMF experiment 497 has measured the parity-violating longitudinal analyzing power Az in p→p elastic scattering at 221.3 MeV incident proton energy. This comprehensive paper includes details of corrections, some magnitude comparable to itself, required arrive final result. The largest correction was for effects first moments transverse polarization. addition result, Az=[0.84±0.29(stat.)±0.17(syst.)]×10−7, parity-violation experimental data base greatly improves constraints on weak...