A5103161348- Sepsis Diagnosis and Treatment
- Immune Response and Inflammation
- Neurological diseases and metabolism
- Plant Pathogens and Fungal Diseases
- Plant Disease Resistance and Genetics
- Glycosylation and Glycoproteins Research
- Blood properties and coagulation
- Coenzyme Q10 studies and effects
- Photochromic and Fluorescence Chemistry
- Physiological and biochemical adaptations
- Long-Term Effects of COVID-19
- Inflammation biomarkers and pathways
- Fungal Infections and Studies
- Estrogen and related hormone effects
- Adipokines, Inflammation, and Metabolic Diseases
- Botanical Studies and Applications
- Diet, Metabolism, and Disease
- Zebrafish Biomedical Research Applications
- Turfgrass Adaptation and Management
- Hematological disorders and diagnostics
- Clusterin in disease pathology
- CRISPR and Genetic Engineering
- Flowering Plant Growth and Cultivation
- Phytochemistry and biological activity of medicinal plants
- Infectious Diseases and Mycology
Wenzhou Medical University
2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2025
Jiangsu University
2015-2024
Affiliated Hospital of Jiangsu University
2016-2024
Fujian Medical University
2021-2023
First Affiliated Hospital of Fujian Medical University
2021-2023
Soochow University
2021
First Affiliated Hospital of Soochow University
2021
Institute of Bast Fiber Crops
2019-2020
Beijing Institute of Technology
2020
Abstract Quantitative real-time PCR (qPCR) is commonly used for deciphering gene functions. For effective qPCR analyses, suitable reference genes are needed normalization. The objective of this study to identify the appropriate gene(s) analyses leaves and roots ramie ( Boehmeria nivea L.), an important natural fiber crop. To accomplish goal, we investigated expression patterns eight common plant in under five abiotic stresses, hormonal treatments, one biotic stress. relative stabilities were...
Abstract Lung cancer is recognized as the leading cause of cancer-related death worldwide, with non-small cell lung (NSCLC) being predominant subtype, accounting for approximately 85% cases. Although great efforts have been made to treat cancer, no proven method has found thus far. Considering β, β-dimethyl-acryl-alkannin (ALCAP2), a natural small-molecule compound isolated from root Lithospermum erythrorhizon. We that adenocarcinoma (LUAD) proliferation and metastasis can be significantly...
Herein, we report our work exploring the essential requirements for fluorophore selection during development of various fluorescence applications. We assembled a library chromone-derived fluorophores with diverse structure–fluorescence properties, which allowed us to choose pairs similar structures but differing properties and compared performance selected in three types commonly used found that standard suitable is variable depending on application. (1) In imaging, strong constant under...
Increased vascular permeability and inflammation are principal hallmark of sepsis. Moesin (MSN) is a membrane-associated cytoskeleton protein crucial for the endothelial function. This study aimed at evaluating role MSN in injury during process sepsis.Serum septic patients was measured by ELISA. BALB/c mice were injected with different doses lipopolysaccharide (LPS) or underwent cecal ligation single double puncture (CLP) to mimic sublethal lethal After treatment, their serum PCT levels, wet...
We aimed to compared the clinical features of acute respiratory distress syndrome (ARDS) induced by COVID-19 and H7N9 virus infections.Clinical data 100 patients with 46 were retrospectively analyzed.Elevated inflammatory indices coagulation disorders more common in COVID-19-ARDS group than H7N9-ARDS group. The median interval from illness onset ARDS development was shorter H7N9-ARDS. PaO2/FiO2 level lower H7N9-ARDS, whereas Sepsis-related Organ Failure Assessment score higher COVID-19-ARDS....
Abstract Primary familial brain calcification (PFBC) is a neurogenetic disorder characterized by bilateral calcified deposits in the brain. We previously identified that MYORG as first pathogenic gene for autosomal recessive PFBC, and established Myorg -KO mouse model. However, mice developed calcifications until nine months of age, which limits their utility facile PFBC model system. Hence, whether there another typical animal mimicking phenotypes an early stage still remained unknown. In...
Rhubarb has been used as an evacuant for thousands of years. However, recent research indicated that rhubarb inhibits inflammation and protects organ function. In the current study, use was investigated in patients with intra-abdominal hypertension (IAH). Specifically, its dual role attenuating lung bowel injury by catharsis inhibiting evaluated. Patients glycerin group (n=56) received 110 ml enema coloclysis once daily 7 to 9 days. were treated a mixture 0.3 g/kg body weight powder 100 warm...
We presented two cases of Cryptococcus albidus fungemia in men who were identified with millary nodules by chest computed tomography (CT). They present cough and fever, no other abnormal physical examination. The patients treated successfully a week-long course voriconazole tablets. Accurate microbiological diagnosis NGS effective therapy as antifungal treatment tablet are critical for C infection. Total 18 infection from2000 years to now, eight which invasive infection, ten noninvasive None...
Introduction Hereditary spastic paraplegias (HSPs) are uncommon but not rare neurodegenerative diseases. More than 100 pathogenic genes and loci related to paraplegia symptoms have been reported. HSPs the same core clinical features, including progressive spasticity in lower limbs, though heterogeneous (eg, signs, MRI gene mutation). The age of onset varies greatly, from infant adulthood. In addition, slow variable rates disease progression patients with HSP represent a substantial challenge...
The oomycete Phytopythium vexans is a causative agent of patch canker, damping-off, and crown, stem, root rot in many economically important plants. P. HF1 was isolated China, where it caused brown ramie, fiber crop broadly cultivated Asia. genome sequenced by combination technologies producing short (Illumina HiSeq X) long (PacBio RS) reads. 41.73 Mbp long, assembled into 44 contigs. It has GC content 58.17% contains 13,051 predicted coding genes, including 1,461 putative virulence genes...
Objective To investigate the changes of platelet function and prognosis at early phase sepsis. Methods A total 41 septic patients in ICU Affiliated Hospital Jiangsu University from January 2014 to April 2016 were divided into sepsis group (n = 18) severe 23) according severity their illness. Fifteen healthy volunteers served as control group. The general condition, hemogram, inflammatory markers, parameters all enrolled subjects, well acute disease physiology chronic health evaluation...