A5103268043- Eicosanoids and Hypertension Pharmacology
- Tryptophan and brain disorders
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Natural Compounds in Disease Treatment
- Natural product bioactivities and synthesis
- Inflammatory mediators and NSAID effects
- Alcohol Consumption and Health Effects
- Berberine and alkaloids research
- Pharmacological Effects of Natural Compounds
- Analytical Chemistry and Sensors
- Autophagy in Disease and Therapy
- Biochemical Acid Research Studies
- Cardiovascular Disease and Adiposity
- Chemotherapy-induced organ toxicity mitigation
- Reconstructive Surgery and Microvascular Techniques
- Abdominal vascular conditions and treatments
- Intraperitoneal and Appendiceal Malignancies
- Biomedical Ethics and Regulation
- Heme Oxygenase-1 and Carbon Monoxide
- Gastrointestinal Bleeding Diagnosis and Treatment
- Dietary Effects on Health
- Barrier Structure and Function Studies
- Erythrocyte Function and Pathophysiology
- Diabetic Foot Ulcer Assessment and Management
Wenzhou Medical University
2023-2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2023-2025
Kunming Medical University
2019-2022
First Affiliated Hospital of Kunming Medical University
2019-2022
Air Force Medical University
2012-2021
Xijing Hospital
2012-2021
Inserm
2010
Ningbo University
2010
The development of suitable drug delivery carriers is significant in biomedical applications to improve the therapeutic efficiency. Recent progress nanotechnological fields, paved way for formulation variety carriers. brain disorders such as ischemic stroke, cancer, and CNS were poorly treated due presence blood barrier that hinders passage drugs brain. Hence, formulated should have ability cross blood-brain (BBB) stroke treatment. In present work, we synthesized PLGA functionalized magnetic...
Metformin exhibits therapeutic potential in behavioural deficits induced by methamphetamine (METH) rats. Emerging studies suggest gut microbiota may impact psychiatric symptoms, but there is no direct evidence supporting metformin's participation the pathophysiology of withdrawal symptoms via modulation microbiota.In order to define functional impacts and metformin during METH withdrawal, we utilized a combination fecal transplantation (FMT), high-throughput sequencing, untargeted...
Melatonin, an indolamine secreted by the pineal gland, as well most of organs and tissues, provides a strong defense against septic myocardial injury. However, underlying mechanism has not been fully illustrated. In this study, we investigated protective effects melatonin lipopolysaccharide (LPS)-induced injury mechanisms involved. Mice were intraperitoneally injected with LPS to induce or shock model, depending on dose LPS. Melatonin was given (20 mg/kg/day, via intraperitoneal injection)...
Berberine has shown an outstanding antioxidant activity, however the low bioavailability limits its applications in pharmaceutical platforms. Therefore, this paper, after fabrication of berberine-HSA nanoparticles by desolvation method, they were well characterized TEM, SEM, DLS, and FTIR techniques. Afterwards interaction HSA berberine was evaluated molecular docking analysis. Finally, activity against H₂O₂-induced oxidative stress cultured neurons as a model AD cellular assays. The results...
Heroin addiction and withdrawal have been associated with an increased risk for infectious diseases psychological complications. However, the changes of metabolites in heroin addicts during remain largely unknown.A total 50 participants including 20 acute abstinence stage, 15 protracted stage healthy controls, were recruited. We performed metabolic profiling plasma samples based on ultraperformance liquid chromatography coupled to tandem mass spectrometry explore potential biomarkers...
Abstract Epithelial ovarian cancer (EOC) contributes the majority of death cases among various malignancies. Although a standard method treatment is surgical removal malignant tissue followed by platinum‐based chemotherapy, group patients does not respond appropriately to cisplatin. An appropriate response cisplatin has been linked with nucleotide excision repair mechanism. The present study aims investigate role polymorphisms in DNA genes, cross‐complementation 1 (ERCC1) susceptibility EOC...
An 82-year patient presented with nausea, coffee-ground emesis, melena and hematochezia on July 10, 2011. The received blood transfusion 11, continued to bleed from 12 17. underwent upper gastrointestinal endoscopy 16. There were no abnormalities in the esophagus, stomach duodenum. Then shortness of breath, extreme fear, fatigue, hypotension, sweating, cold limbs. Dopamine, as well pressurised infusion packed red cells fresh frozen plasma given maintain pressure. CT angiography (CTA)...
Abstract The purpose of this study was to compare the reconstructive outcomes soft‐tissue defects around foot and ankle with vaccum sealing drainage (VSD) or induction membrane (IM) cement formation attempt provide an optimal strategy for elderly patients. A retrospective review all continuous patients reconstruction using different flaps from October 2016 2020 performed. Based on way, were divided into two groups: VSD group ( n = 26) IM 27). Outcomes assessed according size defect,...
In this article the gas diffusion mechanisms of limiting current oxygen sensors was studied. For a sensor which pore diameter d is about 30μm, Il quite linear with ln (1-X02) rather than X02 at 1 atm pressure, it showed normal mechanism more dominant Knudsen one. However low changed variation total pressure P. This reveals neither simply belonged to nor pressure. It may be mixed diffusion.
ABSTRACT Objective Metformin exhibits therapeutic potential in behavioural deficits induced by methamphetamine (METH) rats. Emerging studies suggest gut microbiota may impact psychiatric symptoms, but there is no direct evidence supporting metformin’s participation the pathophysiology of withdrawal symptoms via modulation microbiota. Mehods In order to define functional contributions and metformin during METH withdrawal, we utilized a combination fecal transplantation (FMT), high-throughput...
An 82‑year‑old female was diagnosed with ovarian cancer in May 2004. Following gynecological surgery, pathological evaluation showed stage IIIC epithelial cancer. From June 2004 to January 2005, the patient received six cycles of conventional treatment combined intravenous paclitaxel (Taxol®) and cisplatin. The developed abdominal distension experienced a gradual deterioration health during 2007, admission First Affiliated Hospital 2007. presented severe breathing difficulty on 15 appeared...
Objective: Metformin exhibits therapeutic potential in behavioural deficits rats induced by methamphetamine (METH). Emerging studies suggest gut microbiota may impact psychiatric symptoms, but there is no direct evidence supporting metformin’s modulation of and participation the pathophysiology withdrawal symptoms.Design: In order to define functional contributions metformin during METH withdrawal, we used a combination fecal transplantation (FMT), high-throughput sequencing, untargeted...