A5034177782- Photonic and Optical Devices
- Advanced Fiber Optic Sensors
- Tryptophan and brain disorders
- Advanced Photonic Communication Systems
- Advanced Fiber Laser Technologies
- Photonic Crystals and Applications
- Optical Network Technologies
- Gut microbiota and health
- Neural Networks and Reservoir Computing
- Neuroinflammation and Neurodegeneration Mechanisms
- Plasmonic and Surface Plasmon Research
- Extracellular vesicles in disease
- Optical Coatings and Gratings
- Semiconductor Lasers and Optical Devices
- 2D Materials and Applications
- Nanowire Synthesis and Applications
- Clostridium difficile and Clostridium perfringens research
- Semiconductor Quantum Structures and Devices
- Immune Cell Function and Interaction
- HIV/AIDS Research and Interventions
- MicroRNA in disease regulation
- NF-κB Signaling Pathways
- Stress Responses and Cortisol
- HIV Research and Treatment
- Photorefractive and Nonlinear Optics
Tianjin University
2023-2025
Ministry of Education of the People's Republic of China
2024-2025
Yunnan University
2022-2025
Chinese University of Hong Kong
2019-2024
Xinjiang Normal University
2024
The University of Tokyo
2024
Academy of Opto-Electronics
2024
Jilin Agricultural University
2024
Kunming Medical University
2019-2023
First Affiliated Hospital of Kunming Medical University
2019-2023
Microring resonators, due to their ability enable robust strong light–matter interactions within structures, have garnered substantial interest for utility in sensing applications, particularly the realm of gas detection. However, there is an inherent trade-off between a microring resonator's quality factor and confinement air, making it difficult balance them. Here, we demonstrate novel solution with suspended nanomembrane silicon (SNS) resonator. This resonator has ultrathin sub-wavelength...
Abstract Hyperuniform disordered solids (HUDS) waveguides, a type of emerging artificial photonic bandgap (PBG) devices, are demonstrated to possess large, complete, and isotropic PBGs, being promising for developing applications in optoelectronics, nonlinear optics, sensing. However, optical losses HUDS waveguides usually limited by giant light scattering from the irregular distribution cells. Herein, waveguide devices with low large PBGs exploring morphology‐engineering...
A very-high-bandwidth integrated silicon microring modulator (MRM) designed on a commercial photonics (SiP) platform for C-band operation is presented. The MRM has 3 dB electro-optic (EO) bandwidth of over 67 GHz and features small footprint 24 µm × 70 µm. Using the MRM, we demonstrate intensity modulation-direct detection (IM-DD) transmission with 4-level pulse amplitude modulation (PAM-4) signaling 100 Gbaud. By utilizing optical peaking effect negative chirp in extend distance, which...
Mode-division multiplexing (MDM) in optical fibers enables multichannel capabilities for various applications, including data transmission, quantum networks, imaging, and sensing. However, high-dimensional fiber systems, usually necessity bulk-optics approaches launching different orthogonal modes into the fiber, multiple-input multiple-output digital electronic signal processing at receiver to undo arbitrary mode scrambling introduced by coupling transmission a multi-mode fiber. Here we...
Chemoresistance remains a major obstacle to successful treatment of breast cancer. Although soluble tumor necrosis factor-α (sTNF-α) has been implicated in mediating drug-resistance human cancers, whether transmembrane (tmTNF-α) plays role chemoresistance unclear. Here we found that over 50% studied patients expressed tmTNF-α at high levels cancer tissues and expression positively correlated with resistance anthracycline chemotherapy. Alteration changed the sensitivity primary cells cell...
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of that expand in cancer, inflammation, and infection negatively regulate inflammation the immune response. Heart failure (HF) is complex clinical syndrome wherein induction incomplete resolution can potentially contribute to HF development progression. However, role MDSCs remains unclear.The percentage patients with mice pressure overload-induced using isoproterenol infusion or transverse aortic constriction (TAC) was...
Integrating light emission and detection functionalities using efficient III-V materials on Si wafers is highly desirable for Si-based photonic integrated circuits. To fulfill the need of high-performance photodetectors (PDs) monolithically photonics, we demonstrate PDs directly grown a InP/Si-on-insulator (SOI) platform parallel to device layer in variety dimensions. Device characteristics including 3 dB bandwidth beyond 40 GHz, open eye diagrams at Gb/s, dark current 0.55 nA, responsivity...
Integrated spectrometers with both wide optical bandwidths and high spectral resolutions are required in applications such as domain coherence tomography (SD-OCT). Here we propose a compact integrated scanning spectrometer by using tunable micro-ring resonator (MRR) single arrayed waveguide grating for operation the 1265–1335-nm range. The resolution of is determined quality factor MRR, bandwidth defined free range grating. on-chip germanium photodetectors, which enable direct electrical...
Metformin exhibits therapeutic potential in behavioural deficits induced by methamphetamine (METH) rats. Emerging studies suggest gut microbiota may impact psychiatric symptoms, but there is no direct evidence supporting metformin's participation the pathophysiology of withdrawal symptoms via modulation microbiota.In order to define functional impacts and metformin during METH withdrawal, we utilized a combination fecal transplantation (FMT), high-throughput sequencing, untargeted...
Seamlessly integrating III-V active devices with Si passive components in a monolithic manner is the key for fully integrated photonics. In this article, we demonstrate high-performance photodetectors directly grown on industry-standard (001)-oriented silicon-on-insulator (SOI) wafers and intimately coupled waveguides. The Si-waveguide-coupled feature low dark current of 60 pA corresponding to density <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"> <mml:mrow...
Soybean is one of the important oil crops and a major source protein lipids. Drought can cause severe soybean yields. Dehydrin (DHN) subfamily LEA proteins that play an role in plant responses to abiotic stresses. In this study,
This article addresses the past, present, and future status of hybrid plasmonic waveguides (HPWs). It presents a comprehensive review HPW-based photonic integrated circuits (PICs), covering both passive active devices, as well potential application on-chip devices. (HPWICs) are compatible with complementary metal oxide semiconductor technology, their matched refractive indices enables adaptation existing fabrication processes for silicon-on-insulator designs. HPWs combine waveguide...
Hybrid integration of two-dimensional (2D) materials holds great promise for realizing novel optoelectronic components on planar dielectric waveguides. Functional devices based 2D layered transition metal dichalcogenides (TMDs) offer the advantages low dark current and high speed. In this work, we propose experimentally demonstrate a high-speed hybrid integrated PtSe2 silicon nitride waveguide photodetector. The light is guided in channel by structure principle bound states continuum (BICs)....
Abstract Motivated by applications in mobile optical sensing, ultracompact high‐resolution integrated spectrometers have attracted much interest. Here, a speckle spectrometer, comprising linear coherent network formed mutually coupled Mach–Zehnder interferometers and nonidentical microring resonators, is proposed demonstrated. Deep‐etched grating lines used as mirrors on the edges of increase effective path lengths. The spectrometer realized silicon nitride platform, operating at 776 nm...
Abstract Psychiatric disorders such as anxiety and depression precipitated by substance use occurred during both withdrawal. Exosomes play significant roles in biological functions regulate numerous physiological pathological processes various diseases, particular (SUDs) other psychiatric disorders. To better understand the role of exosomal miRNAs pathology symptoms patients with SUDs, we first isolated circulating exosomes from heroin-dependent (HDPs) methamphetamine-dependent (MDPs)...
Silicon microring modulators (MRM) are a promising technology for next generation datacenter interconnects, where migration to higher data capacities will require the increasing use of wavelength division multiplexing (WDM). However periodic repetition resonances, and limited free-spectral range (FSR) MRMs, can limit number WDM channels when we selectivity MRM modulate particular from frequency comb sources or other multi-wavelength propagating in bus waveguide. In this paper, realize an...
Methamphetamine (MA) abuse results in neurotoxic outcomes, including increased anxiety and depression. Studies have reported an association between MA exposure anxiety, nonetheless, the underlying mechanism remains elusive. In present study, we developed a mouse model of anxiety-like behavior induced by administration. RNA-seq was then performed to profile gene expression patterns hippocampus (HIPP), differentially expressed genes (DEGs) were significantly enriched signaling pathways related...
Abstract Space‐division multiplexing (SDM) is one of the key enabling technologies to increase capacity fiber communication systems. However, implementing SDM‐based systems using multimode has been challenging with need for compact, low‐cost, and scalable mode de/multiplexer (DE/MUX). Here a novel integrated MUX few‐mode fibers (FMFs) presented which can launch up eight spatial polarization channels. The new design composed 2D grating coupler (MMGC), highly compact spot size converters...
Leveraging the low linear and nonlinear absorption loss of silicon at mid-infrared (mid-IR) wavelengths, photonic integrated circuits (PICs) have attracted significant attention for mid-IR applications including optical sensing, spectroscopy, optics. However, PICs typically show moderate performance compared to state-of-the-art devices operating in telecommunication band. Here, we proposed demonstrated suspended nanomembrane (SNS) with light guiding within deep-subwavelength waveguide...
Abstract Low-dimensional material-based heterogeneous silicon photonics has attracted significant attention due to their applications in developing integrated optoelectronic devices from the telecommunication band mid-infrared wavelengths. However, study of waveguide components with low-dimensional materials for mode-division multiplexing (MDM) mostly remains its infancy. In this paper, we demonstrated waveguide-integrated spatial mode filters by integrating subtly designed ten-layer PtSe 2...
Subwavelength grating structures are widely used in integrated optical devices due to their compact footprints and flexible refractive index tailoring. In this paper, we present a subwavelength (SWG) coupler for 70-nm-thick silicon waveguide without the upper cladding. The device was designed by using particle swarm optimization algorithm 3D finite-difference time-domain simulation. Experimental measurements show that SWG with minimum feature size of ∼210 nm has peak coupling efficiency -7.0...