Cheng Chen

ORCID: 0000-0003-0561-5226
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About
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Research Areas
  • Photoreceptor and optogenetics research
  • Advanced Fluorescence Microscopy Techniques
  • Photochemistry and Electron Transfer Studies
  • Functional Brain Connectivity Studies
  • Advanced battery technologies research
  • Spectroscopy and Quantum Chemical Studies
  • Neural dynamics and brain function
  • Photosynthetic Processes and Mechanisms
  • Advanced Battery Materials and Technologies
  • Luminescence and Fluorescent Materials
  • Mental Health Research Topics
  • Neuroinflammation and Neurodegeneration Mechanisms
  • EEG and Brain-Computer Interfaces
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Photochromic and Fluorescence Chemistry
  • Molecular Sensors and Ion Detection
  • Advanced Neuroimaging Techniques and Applications
  • Neuroscience and Neuropharmacology Research
  • Perovskite Materials and Applications
  • Pressure Ulcer Prevention and Management
  • Wound Healing and Treatments
  • Advanced Battery Technologies Research
  • Face Recognition and Perception
  • Diabetic Foot Ulcer Assessment and Management
  • Nerve injury and regeneration

Oregon State University
2017-2025

Renmin Hospital of Wuhan University
2015-2025

Affiliated Eye Hospital of Wenzhou Medical College
2025

Wenzhou Medical University
2025

Zhejiang Lab
2025

Wuhan University
2015-2025

Soochow University
2022-2024

China University of Mining and Technology
2024

First Affiliated Hospital of Kunming Medical University
2021-2023

Kunming Medical University
2021-2023

We report a low-cost water-in-salt electrolyte, of 30 m ZnCl2, which enables dendrite-free Zn metal anode to possess high coulombic efficiency (CE). In asymmetric Zn‖Zn cells with limited mass plated as the working electrode, ZnCl2 WiSE improves average CE 95.4% from 73.2% in 5 ZnCl2.

10.1039/c8cc07730d article EN Chemical Communications 2018-01-01

Abstract A great challenge for all aqueous batteries, including Zn‐metal is the parasitic hydrogen evolution reaction on low‐potential anode. Herein, we report formula of a highly concentrated electrolyte that mitigates by transforming water molecules more inert. The comprises primarily ZnCl 2 and LiCl as an additive, both which are inexpensive salts. O–H covalent bonds in get strengthened chemical environment has fewer bonding interactions greater number Zn–Cl superhalides, suggested...

10.1002/cey2.70 article EN cc-by Carbon Energy 2020-08-17

Amine groups are common constituents of organic dyes and play important roles in tuning fluorescence properties. In particular, intensive research works have demonstrated the tendency capabilities amines influencing chromophore brightness. Such properties been explained by multiple mechanisms spanning from twisted intramolecular charge transfer (TICT) to energy gap law beyond, which introduce additional nonradiative dissipation pathways. this review, we aim provide a focused overview...

10.3390/chemosensors11020087 article EN cc-by Chemosensors 2023-01-23

Abstract Here, four MOFs, namely Sc-TBAPy, Al-TBAPy, Y-TBAPy, and Fe-TBAPy (TBAPy: 1,3,6,8-tetrakis( p -benzoic acid)pyrene), were characterized evaluated for their ability to remediate glyphosate (GP) from water. Among these materials, Sc-TBAPy demonstrates superior performance in both the adsorption degradation of GP. Upon light irradiation 5 min, completely degrades 100% GP a 1.5 mM aqueous solution. Femtosecond transient absorption spectroscopy reveals that exhibits enhanced charge...

10.1038/s41467-024-45546-y article EN cc-by Nature Communications 2024-02-17

Abstract The electrochemical stability window of water is known to vary with the type and concentration dissolved salts. However, underlying influence ions on thermodynamic aqueous solutions has not been fully understood. Here, we investigated electrolytic behaviors electrolytes as a function different ions. Our findings indicate that high ionic potentials, i.e., charge density, promote formation their respective hydration structures, enhancing reactions via an inductive effect, particularly...

10.1002/anie.202401555 article EN Angewandte Chemie International Edition 2024-03-18

Advancements in single-cell multimodal techniques have greatly enhanced our understanding of disease-relevant loci identified through genome-wide association studies (GWASs). To investigate the biological connections between eye and brain, we integrated bulk multiomic profiles with GWAS summary statistics for eight neuropsychiatric five ocular diseases. Our analysis uncovered latent factors explaining 61.7% genetic variance across these 13 diseases, revealing diverse correlational patterns...

10.1038/s41398-025-03243-4 article EN cc-by-nc-nd Translational Psychiatry 2025-01-25

Chemistry studies the composition, structure, properties, and transformation of matter. A mechanistic understanding pertinent processes is required to translate fundamental knowledge into practical applications. The current development ultrafast Raman as a powerful time-resolved vibrational technique, particularly femtosecond stimulated spectroscopy (FSRS), has shed light on structure-energy-function relationships various photosensitive systems. This Perspective reviews recent work...

10.1021/acs.jpclett.8b00373 article EN The Journal of Physical Chemistry Letters 2018-05-25

Schizophrenia is a disorder characterized by functional dysconnectivity among distributed brain regions. However, it unclear how causal influences large-scale networks are disrupted in schizophrenia. In this study, we used dynamic modeling (DCM) to assess the hypothesis that there aberrant directed (effective) connectivity within and between three key (the dorsal attention network, salience network default mode network) schizophrenia during working memory task. Functional MRI data an n-back...

10.1016/j.nicl.2017.12.006 article EN cc-by-nc-nd NeuroImage Clinical 2017-12-06

Abstract Biofilms are microbial communities growing on surfaces, and ubiquitous in nature, bioreactors, human infection. Coupling between physical, chemical, biological processes is known to regulate the development of biofilms; however, current experimental systems do not provide sufficient control environmental conditions enable detailed investigations these complex interactions. We developed a novel planar flow cell that supports biofilm growth under two‐dimensional fluid conditions. This...

10.1002/bit.23234 article EN Biotechnology and Bioengineering 2011-06-08

Energy dissipation following photoexcitation is foundational to photophysics and chemistry. Consequently, understanding such processes on molecular time scales holds paramount importance. Femtosecond stimulated Raman spectroscopy (FSRS) has been used study the structure-function relationships but usually Stokes side. Here, we perform both anti-Stokes FSRS track energy excited-state proton transfer (ESPT) for photoacid pyranine in aqueous solution. We reveal biphasic vibrational cooling fs-ps...

10.1021/acs.jpclett.7b00322 article EN The Journal of Physical Chemistry Letters 2017-02-14

Tracking molecular motions in real time remains a formidable challenge science and engineering fields because the experimental methodology requires simultaneously high spatial temporal resolutions. Building on early successes future potential of femtosecond stimulated Raman spectroscopy (FSRS) as structural dynamics technique, we present comprehensive study line shapes photosensitive molecule solution with tunable pump probe pulses. Following 400 nm electronic excitation, model photoacid...

10.1021/acs.jpca.7b04404 article EN The Journal of Physical Chemistry A 2017-07-05

The quest for capturing molecular movies of functional systems has motivated scientists and engineers decades. A fundamental understanding electronic nuclear motions, two principal components the Schrödinger equation, potential to enable de novo rational design targeted functionalities machines. We discuss development application a relatively new structural dynamics technique, femtosecond stimulated Raman spectroscopy with broadly tunable laser pulses from UV near-IR region, in tracking...

10.1063/1.5128388 article EN The Journal of Chemical Physics 2019-11-27

Green fluorescent protein (GFP) has revolutionized bioimaging and life sciences. Its successes have inspired modification of the chromophore structure environment to tune emission properties, but outside cage, is essentially non-fluorescent. In this study, we employ tunable femtosecond stimulated Raman spectroscopy (FSRS) transient absorption (TA) map energy dissipation pathways GFP model (HBDI) in basic aqueous solution. Strategic tuning pump 550 nm exploits band enhance excited state...

10.1039/c9cp01077g article EN Physical Chemistry Chemical Physics 2019-01-01

Methamphetamine (MA) abuse results in neurotoxic outcomes, including increased anxiety and depression. Studies have reported an association between MA exposure anxiety, nonetheless, the underlying mechanism remains elusive. In present study, we developed a mouse model of anxiety-like behavior induced by administration. RNA-seq was then performed to profile gene expression patterns hippocampus (HIPP), differentially expressed genes (DEGs) were significantly enriched signaling pathways related...

10.3389/fnmol.2022.829886 article EN cc-by Frontiers in Molecular Neuroscience 2022-02-28

Rechargeable aqueous zinc-ion batteries (AZIBs) are close complements to lithium-ion for next-generation grid-scale applications owing their high specific capacity, low cost, and intrinsic safety. Nevertheless, the viable cathode materials (especially manganese oxides) of AZIBs suffer from poor conductivity inferior structural stability upon cycling, thereby impeding practical applications. Herein, a facile synthetic strategy bead-like oxide coated with carbon nanofibers (MnOx-CNFs) based on...

10.1021/acsami.2c03170 article EN ACS Applied Materials & Interfaces 2022-04-07

Abstract Severe sleep deprivation (SD) has been highly associated with systemic energy wasting, such as lipid loss and glycogen depletion. Despite immune dysregulation neurotoxicity observed in SD animals, whether how the gut-secreted hormones participate SD-induced disruption of homeostasis remains largely unknown. Using Drosophila a conserved model organism, we characterize that production intestinal Allatostatin A (AstA), major gut-peptide hormone, is robustly increased adult flies...

10.1038/s41421-023-00541-3 article EN cc-by Cell Discovery 2023-05-23

Compact fluorescent molecules with meta-positioned donor (D) and acceptor (A) groups have recently demonstrated extraordinary photophysical properties such as red emission large Stokes shifts for advanced bioimaging optoelectronic applications. However, it remains elusive how simple D–A configuration can give rise to these unique which para isomers lack. Herein, we unlock the fundamental photophysics its origin of “meta effect” by systematically investigating series meta chromophores varying...

10.26434/chemrxiv-2025-56x1p preprint EN cc-by-nc-nd 2025-02-26

Disorganized thinking is a prominent feature of schizophrenia that becomes persistent in the presence treatment resistance. Disruption default mode network (DMN), which regulates self-referential thinking, now well-established schizophrenia. However, we do not know if DMN disruption affects disorganization and contributes to treatment-resistant (TRS). This study investigated 48 TRS, 76 non-TRS, 64 healthy controls (HC) using spatiotemporal approach with resting-state functional magnetic...

10.1093/schbul/sbaf018 article EN cc-by Schizophrenia Bulletin 2025-03-03

Hypericin from St. John’s wort has been used as a potent photosensitizer, but its working mechanism remains elusive which hinders rational design for improved functionality. We implement ultrafast spectroscopy and quantum calculations to track the excited‐state dynamics in an intricate hydrogen‐bonding network of hypericin solution. Using femtosecond transient absorption (fs‐TA), we excited state intramolecular proton transfer (ESIPT) via previously unreported blueshift long‐wavelength...

10.1002/chem.202500639 article EN Chemistry - A European Journal 2025-03-04
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