A5053753970- Insect Pheromone Research and Control
- Plant and animal studies
- Immune Cell Function and Interaction
- Neurobiology and Insect Physiology Research
- IL-33, ST2, and ILC Pathways
- Bone fractures and treatments
- Orthopedic Infections and Treatments
- Hip and Femur Fractures
- Airway Management and Intubation Techniques
- Immune Response and Inflammation
- Asthma and respiratory diseases
- Forest Insect Ecology and Management
- Respiratory Support and Mechanisms
- Pelvic and Acetabular Injuries
- Autoimmune and Inflammatory Disorders Research
- Immunotherapy and Immune Responses
- Cardiac Arrest and Resuscitation
University of Chicago
2024
Yale University
2020
Wellesley College
2018
Bioqual
2009
Preston University
1986
Middlesex Hospital
1986
University College London
1986
University of Exeter
1986
Institute of Dermatology
1986
Newcastle upon Tyne Hospital
1986
Inhibiting mitochondrial oxidant production after surgical fixation of an intra-articular fracture prevents osteoarthritis in a porcine model.
How insects navigate complex odor plumes, where the location and timing of packets are uncertain, remains unclear. Here we imaged plumes simultaneously with freely-walking flies, quantifying how behavior is shaped by encounters individual packets. We found that navigation was stochastic did not rely on continuous modulation speed or orientation. Instead, flies turned stochastically stereotyped saccades, whose direction biased upwind prior encounters, while magnitude rate saccades remained...
Understanding the initiation of T-helper (Th)-2 immunity is crucial for addressing allergic diseases that have been linked to commensal microbiota. However, Th2 responses are notably absent from known host-microbiota intestinal immune circuits. Notably, protist
ABSTRACT Insects find food, mates, and egg-laying sites by tracking odor plumes swept complex wind patterns. Previous studies have shown that moths flies localize surging upwind at onset turning cross- or downwind offset. Less clear is how, once within the expanding cone of plume, insects use their brief encounters with individual packets, whose location timing are random, to progress towards source. Experiments theory suggested might assist navigation, but connecting behaviors has been...
Background Co-stimulatory molecules play a critical role in the development of cellular immunity. Understanding how costimulatory pathways interact and influence immune response is for generation an effective HIV vaccine. We evaluated ability intravenous administration blocking monoclonal antibodies (mAb) directed against negative co-stimulatory molecule, CTLA-4, agonist mAb positive 41BB, to augment intramuscular SIV DNA immunizations. then tested these responses impact SIVmac251 challenge.
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