A5069503434- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Eating Disorders and Behaviors
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Attention Deficit Hyperactivity Disorder
- Child Nutrition and Feeding Issues
- Posttraumatic Stress Disorder Research
- Migration, Health and Trauma
- Tryptophan and brain disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Child Abuse and Trauma
- Neural and Behavioral Psychology Studies
- Child and Animal Learning Development
- Healthcare professionals’ stress and burnout
- Body Image and Dysmorphia Studies
- Microscopic Colitis
- Urticaria and Related Conditions
- Multiple Sclerosis Research Studies
- Acute Lymphoblastic Leukemia research
- Empathy and Medical Education
- Developmental and Educational Neuropsychology
- Perfectionism, Procrastination, Anxiety Studies
- Adolescent and Pediatric Healthcare
Hospital Clínic de Barcelona
2017-2025
Fundació Clínic per a la Recerca Biomèdica
2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2025
Karolinska Institutet
2015-2020
Stockholm Health Care Services
2018-2020
Stockholm County Council
2018-2019
Tic disorders, including Tourette syndrome (TS) and chronic tic disorders (CTDs), are assumed to be strongly familial heritable. Although gene-searching efforts well under way, precise estimates of risk heritability lacking. Previous controlled family studies were small typically conducted within specialist clinics, resulting in potential ascertainment biases. They also underpowered disentangle genetic from environmental factors that contribute the observed familiality. Twin have been either...
Objectives The usefulness of cases diagnosed in administrative registers for research purposes is dependent on diagnostic validity. This study aimed to investigate the validity and inter-rater reliability recorded diagnoses tic disorders obsessive-compulsive disorder (OCD) Swedish National Patient Register (NPR). Design Chart review randomly selected register controls. Method 100 OCD were from NPR based codes International Classification Diseases (ICD) 8th, 9th 10th editions, together with...
To our knowledge, the association of obsessive-compulsive disorder (OCD) and academic performance has not been objectively quantified.
Social anxiety disorder (SAD) has been linked to academic underachievement, but previous studies had methodological limitations. We investigated the association between SAD and objective indicators of educational performance, controlling for a number covariates unmeasured confounders shared siblings.This population-based birth cohort study included 2 238 837 individuals born in Sweden 1973 1997, followed-up until 2013. Within cohort, 15 755 recorded ICD-10 diagnosis Swedish National Patient...
<h3>Importance</h3> The influence of Tourette syndrome and chronic tic disorders on academic performance has not been objectively quantified. <h3>Objective</h3> To investigate the association with measured educational outcomes, adjusting for covariates unmeasured factors shared between siblings taking common psychiatric comorbidities into account. <h3>Design, Setting, Participants</h3> A population-based birth cohort consisting all individuals born in Sweden from 1976 to 1998 was followed up...
Body dysmorphic disorder (BDD) usually begins during adolescence but little is known about the prevalence, etiology, and patterns of comorbidity in this age group. We investigated prevalence BDD symptoms adolescents young adults. also report on relative importance genetic environmental influences symptoms, risk for co-existing psychopathology.Prevalence was determined by a validated cut-off Dysmorphic Concerns Questionnaire (DCQ) three population-based twin cohorts at ages 15 (n = 6968), 18...
Repetitive and restrictive behaviors (RRB) include simple motor stereotypes, tics complex ritualized rigid that are core symptoms in neurodevelopmental disorders such as obsessive–compulsive disorder (OCD), Tourette syndrome (TS) or autism spectrum (ASD). Sensory phenomena (SP) uncomfortable feelings, including bodily sensations, sense of inner tension, "just-right" perceptions, feelings incompleteness, "urge-only" phenomena, which have been described to precede, trigger, accompany RRB. In...
Abstract Background The impact of obsessive–compulsive disorder (OCD) on objective indicators labour market marginalisation has not been quantified. Methods Linking various Swedish national registers, we estimated the risk three outcomes (receipt newly granted disability pension, long-term sickness absence and unemployment) in individuals diagnosed with OCD between 2001 2013 who were 16 64 years old at date first diagnosis ( n = 267), compared matched general population controls 157 176)....
Individuals with ADHD are at increased risk for poor occupational outcomes. Educational attainment and psychiatric comorbidity may be important contributing factors these outcomes, but the role of is not well characterized. This study aimed to investigate associations between examine influence educational attainment, comorbid developmental disorders intellectual disability on associations.We linked Swedish population graduating from compulsory school 1998-2008 (N = 1.2 millions)...
<h3>Importance</h3> Posttraumatic stress disorder (PTSD) has been associated with impaired educational performance. Previous studies on the could not control for important measured and unmeasured confounders. <h3>Objective</h3> To prospectively investigate association between PTSD objective indicators of attainment across life span, controlling familial factors shared by full siblings, psychiatric comorbidity, general cognitive ability. <h3>Design, Setting, Participants</h3> This...
Abstract Large-scale family studies on the co-occurrence of attention-deficit/hyperactivity disorder (ADHD) and borderline personality (BPD) are lacking. Thus, we aimed to estimate familial co-aggregation clinically ascertained ADHD BPD diagnoses using entire Swedish population. In a register-based cohort design included individuals born in Sweden 1979–2001, identified their during 1997–2013; total, 2,113,902 were analyses. We obtained clinical from inpatient outpatient care. Individuals...
Monitoring "real world" dispensation patterns over time is important to build the evidence base for safe and efficient use of psychotropic drugs. In this study, we aimed comprehensively examine drug dispensations in patients with Tourette chronic tic disorders (TD/CTD) Sweden between 2005 2013.A cohort 6979 TD/CTD was identified through Swedish National Patient Register. Their patterns, collected Prescribed Drug Register, were examined July 1, December 31, 2013. Frequencies further...
Theory of mind (ToM) is the human ability to perceive, interpret, and attribute mental states other people, alteration this cognitive function a core symptom autistic spectrum disorder (ASD). In such neurodevelopmental disorders as childhood-onset obsessive-compulsive (OCD) Tourette syndrome (TS) that can present with dysfunctions, ToM has been less extensively studied, especially in young population. The aim study was compare advanced between groups people diagnosed OCD, TS, or ASD control...
Most people with persistent tics report an unpleasant sensation (premonitory urge) before the tic. In recent years, interest in these sensory phenomena has increased due to their important role behavioural therapy. However, instruments for assessing sensations remain scarce. Among available instruments, Premonitory Urge Tics Scale (PUTS) is most widely used. We examined psychometric properties and factor structure of Spanish-language version PUTS a sample 72 children adolescents Tourette...
La teoría de la mente (ToM) es capacidad humana percibir, interpretar y atribuir los estados mentales las otras personas alteración esta función cognitiva un síntoma nuclear del trastorno espectro autista (TEA). Hay otros trastornos neurodesarrollo como el obsesivo-compulsivo inicio en infancia (TOC) síndrome Tourette (ST), que pueden presentarse con disfunciones cognitivas, ToM ha sido menos estudiada, especialmente población juvenil. El objetivo este estudio fue comparar avanzada entre...
Abstract Background Both maternal and, separately, paternal mental illness are associated with diminished academic attainment among children. However, the differential impacts of diagnostic type and degree parental burden (e.g. one v. both parents affected) on these functional outcomes unknown. Methods Using Swedish national patient (NPR) multi-generation (MGR) registers, 2 226 451 children (1 290 157 pairs), born 1 January 1973–31 December 1997, were followed through 31 2013. Diagnostic...
Most people with persistent tics report an unpleasant sensation (premonitory urge) before the tic. In recent years, interest in these sensory phenomena has increased due to their important role behavioural therapy. However, instruments for assessing sensations remain scarce. Among available instruments, Premonitory Urge Tics Scale (PUTS) is most widely used.