A5032027233- Diabetes Management and Research
- Diabetes Treatment and Management
- Diabetes and associated disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Diet, Metabolism, and Disease
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Thermoregulation and physiological responses
- Gestational Diabetes Research and Management
- Public Health in Brazil
- Diabetes Management and Education
- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Lymphatic System and Diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Obesity, Physical Activity, Diet
- Healthcare professionals’ stress and burnout
- Chronic Kidney Disease and Diabetes
- Peripheral Neuropathies and Disorders
- Renin-Angiotensin System Studies
- Healthcare Regulation
Universidade do Estado do Rio de Janeiro
2014-2025
Fundação Técnico Educacional Souza Marques
2021
Hospital Universitário Pedro Ernesto
2009-2015
Cardiovascular diseases are the most prevalent cause of morbidity and mortality among patients with type 1 or 2 diabetes. The proposed mechanisms that can link accelerated atherosclerosis increased cardiovascular risk in this population poorly understood. It has been suggested an association between hyperglycemia intracellular metabolic changes result oxidative stress, low-grade inflammation, endothelial dysfunction. Recently, epigenetic factors by different types reactions known to be...
To determine the direct medical costs of type 1 diabetes mellitus (T1DM) to National Brazilian Health-Care System (NBHCS) and quantify contribution each individual component total cost.A retrospective, cross-sectional, nationwide multicentre study was conducted between 2008 2010 in 28 public clinics 20 cities. The included 3180 patients with T1DM (mean age 22 years ± 11.8) who were surveyed while receiving health care from NBHCS. mean duration their 10.3 (± 8.0). tests procedures, insulin...
To determine the relationship between adherence to diet reported by patients with type 1 diabetes under routine clinical care in Brazil, and demographic, socioeconomic status, glycemic control cardiovascular risk factors. This was a cross-sectional, multicenter study conducted December 2008 2010 28 public clinics 20 Brazilian cities. The data obtained from 3,180 patients, aged 22 ± 11.8 years (56.3% females, 57.4% Caucasians 43.6% non-Caucasians). mean time since diagnosis 11.7 8.1 years....
Patients with type 2 diabetes (T2D) often experience prolonged periods of asymptomatic hyperglycemia, which significantly increases the risk developing chronic complications related to diabetes. Screening programs for individuals at high T2D provide valuable opportunities not only early diagnosis but also detecting intermediate hyperglycemic states, commonly referred as prediabetes. Interventions aimed preventing in this group can successfully delay or even avoid onset disease and its...
Diabetes is considered an independent risk factor for cognitive impairment and some studies observed through neuropsychological tests that disfunction affects both elderly younger patients with diabetes. The aims of this study were to evaluate the status outpatients type 2 diabetes factors associated impaired function. A cross-sectional was conducted in a group diabetic outpatients. They asked undergo Mini-Mental State Examination (MMSE) during routine ambulatory visits between April 2006...
To determine prospectively the efficacy, tolerability and patient satisfaction of an extended release formulation metformin (metformin XR) in hospital based outpatients with type 2 diabetes mellitus currently treated standard metformin. Patients on immediate either alone or combined other oral agents were switched to XR 500 mg tablets titrated a maximum dose 2000 mg/day Measurements include glucose lipid control, blood pressure, body weight, waist circumference, C-reactive protein, adverse...
The importance of achieving and maintaining an appropriate metabolic control in patients with type 1 diabetes mellitus (DM1) has been established many studies aiming to prevent the development chronic complications. carbohydrate counting method can be recommended as additional tool nutritional treatment diabetes, allowing DM1 have more flexible food choices. This study aimed evaluate influence nutrition intervention use multiple short-acting insulin according on clinical DM1.
To determine the characteristics of clinical care offered to type 1 diabetic patients across four distinct regions Brazil, with geographic and contrasting socioeconomic differences. Glycemic control, prevalence cardiovascular risk factors, screening for chronic complications frequency that recommended treatment goals were met using American Diabetes Association guidelines evaluated.This was a cross-sectional, multicenter study conducted from December 2008 2010 in 28 secondary tertiary public...
Cardiovascular risk factors (CVRF) may cluster in type 1 diabetes, analogously to the metabolic syndrome described 2 diabetes. The threshold of HbA1c above which lipid variables start changing behavior is unclear. This study aims 1) assess dyslipidemia according values; 2) detect a beyond lipids change and 3) compare clustering other non-lipid CVRF among strata individuals with Effects quintiles (1st: ≤7.4%; 2nd: 7.5-8.5%; 3rd: 8.6-9.6%; 4th: 9.7-11.3%; 5th: >11.5%) covariates (gender, BMI,...
Diabet. Med. 29, 1142–1147 (2012) Abstract Aims To examine the temporal trends in frequency of diabetic ketoacidosis at onset compared to other modalities diagnosis Type 1 diabetes Brazil. Methods This was a retrospective, cross‐sectional and multicenter study conducted between December 2008 2010 28 public clinics secondary tertiary levels care, located 20 cities four geographic regions Each clinic provided data extracted from least 50 outpatients with diagnosed 1960 2010, using standardized...
Abstract Aims To investigate if thyroid‐stimulating hormone ( TSH ) levels are associated with any differences in glycaemic control or diabetes‐related complications individuals Type 1 diabetes. Methods This observational, cross‐sectional and multicentre study included patients diabetes for ≥ 5 years, a recent measurement without known previous thyroid disease. Patients were divided into three groups according to levels: 0.4–2.5 mU/l; 2.5–4.4 4.5 mU/l. Results We 1205 mean ± sd age of 23.8...
In recent decades, Diabetes Mellitus has become a severe and growing global public healthcare problem due to the increase of its prevalence, morbidity mortality. Post-transplant diabetes mellitus (PTDM) is complication which takes place after solid organ transplant, incidence widely variable, ranging from 2 53%. Some factors risk PTDM, such as age, ethnicity, cadaver-donor kidney presence hepatitis C virus cytomegalovirus, overweight obesity Immunosuppression scheme established in immediate...
Pain is a frequent symptom in leprosy patients. It may be predominantly nociceptive, as neuritis, or neuropathic, due to injury nerve dysfunction. The differential diagnosis of these two forms pain challenge clinical practice, especially since they often coexist the same patient. A better understanding cytokine profile serve tool assessing patients and also help comprehend pathophysiology pain. Patients with neural (n=22), neuropathic (n=18), neuritis (nociceptive pain) (n=4), without (n=17)...
Double diabetes (DD) describes both individuals with obesity upon diagnosis of type 1 and those who have gained weight during follow-up, although cardiovascular risk factors (CVRF) are not well understood in this group. We aim to evaluate the frequency DD a real-world sample interaction insulin treatment CVRF. Multicentre cross-sectional study 2711 clinical from secondary centres 20 Brazilian cities. Patients duration <5 ≥5 years had similar overweight (20.4 vs. 25 %) obesity, (9.8 6.1 %), p...
OBJETIVO: Avaliar o risco cardiovascular (RCV) em pacientes com diabetes tipo 2 (DM2) de acordo os critérios Framingham, e sua associação outros fatores não incluídos no escore Framingham. DESENHO DO ESTUDO E MÉTODOS: Foram avaliados, corte transverso, 333 DM2 (215 do sexo feminino) média idade 59,6 ± 9,7 anos, acompanhados Serviço Diabetes Metabologia HUPE período março 2004 a fevereiro 2005. A duração conhecida foi 12 (0 43) anos. Foi aplicado Framingham todos para determinação morte por...
Abstract Aim The aim of this study was to determine the relationship between daily frequency self‐monitoring blood glucose and glycaemic control, demographic socio‐economic status in patients with Type 1 diabetes under routine clinical care Brazil. Methods This a cross‐sectional, multi‐centre conducted December 2008 2010 28 public clinics 20 Brazilian cities. data were obtained from 3176 patients, aged 22 ± 11.8 years, whom 56.3% female 57.4% Caucasian. mean time since diagnosis 11.7 8.1...
Com a intensificação do controle glicêmico no tratamento diabetes melito tipo 1 (DM1), houve uma mudança progressiva das causas de mortalidade com destaque para DCV. A identificação fatores risco, como dislipidemia, tornou-se grande importância minimizar o risco complicações crônicas micro e macrovasculares. As diretrizes prevenção doença coronariana em diabetes, geralmente, fazem referência ao 2 (DM2), pouca recomendação específica DM1. Definir alvos terapêuticos ou indicação intervenção...