A5071634647- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Diabetic Foot Ulcer Assessment and Management
- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Wound Healing and Treatments
- Diabetes Management and Education
- Glioma Diagnosis and Treatment
- Pressure Ulcer Prevention and Management
- Nuclear Structure and Function
- Diet and metabolism studies
- Celiac Disease Research and Management
- Ovarian function and disorders
- Hormonal and reproductive studies
- Botulinum Toxin and Related Neurological Disorders
- Digestive system and related health
- Medication Adherence and Compliance
- Pancreatic and Hepatic Oncology Research
- Nitric Oxide and Endothelin Effects
- Cerebrospinal fluid and hydrocephalus
- Mobile Health and mHealth Applications
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2012-2025
Universidade de São Paulo
2009-2021
Hospital São Paulo
2017
Hospital Regional de Presidente Prudente
2016
Universidade Federal do Ceará
2015
Universidade Federal de São Paulo
2015
Hospital Universitário da Universidade de São Paulo
2015
Centro Universitário das Faculdades Metropolitanas Unidas
2012-2015
Fundação Faculdade de Medicina
2015
Universidade do Estado do Rio de Janeiro
2012
Overweight and obesity in youth is a worldwide public health problem. childhood adolescents have substantial effect upon many systems, resulting clinical conditions such as metabolic syndrome, early atherosclerosis, dyslipidemia, hypertension type 2 diabetes (T2D). Obesity the of body fat distribution are still core aspects insulin resistance seem to be physiopathologic links common cardiovascular disease T2D. The earlier appearance clustering risk factors higher time exposure, greater will...
Studies on diabetic foot and its complications involving a significant representative sample of patients in South American countries are scarce. The main objective this study was to acquire clinical epidemiological data large cohort from 19 centers Brazil focus factors that could be associated with the risk ulcer amputation. This presents cross sectional, baseline results BRAZUPA Study. A total 1455 were included. Parameters recorded included age, gender, ethnicity, diabetes...
Body composition determined by dual energy x-ray absorptiometry and the abdominal visceral fat component computed tomographic scanning were examined in women with Cushing's disease compared those obese same anthropometric parameters nonobese women. Patients had no increase total body or trunk region (android) component, but a higher intraabdominal area to subjects. The lean tissue mass was slightly reduced that subjects due significant decrease muscle of legs arms; amounts masses arms most...
OBJECTIVE:To evaluate the impact of a clinical pharmacy program on health outcomes in patients with type 2 diabetes undergoing insulin therapy at teaching hospital Brazil.METHOD: A randomized controlled trial 6-month follow-up period was performed 70 adults, aged 45 years or older, who were taking and had an HbA1c level $8%.Patients control group (CG) (n = 36) received standard care, intervention (IG) 34) individualized pharmacotherapeutic care plan education.The primary outcome measure...
To determine the relationship between adherence to diet reported by patients with type 1 diabetes under routine clinical care in Brazil, and demographic, socioeconomic status, glycemic control cardiovascular risk factors. This was a cross-sectional, multicenter study conducted December 2008 2010 28 public clinics 20 Brazilian cities. The data obtained from 3,180 patients, aged 22 ± 11.8 years (56.3% females, 57.4% Caucasians 43.6% non-Caucasians). mean time since diagnosis 11.7 8.1 years....
Rates of noncommunicable diseases (NCDs) such as type 2 diabetes are escalating in low and middle-income countries Brazil. Scalable primary care-based interventions needed to improve self-management clinical outcomes adults with diabetes. This pilot study examines the feasibility, acceptability, training community health agents (CHAs) Motivational Interviewing (MI)-based counseling for patients poorly controlled a care center São Paulo, Nineteen salaried CHAs participated 32 h MI behavioral...
A inclusão escolar é essencial, devendo ser afiançada a todos como um direito afiançado por lei, e precisa acontecer educação regular, sendo essencial que os educandos com transtorno global de desenvolvimento possam ter esse afiançado, incluído na escola principalmente seja levado em consideração suas necessidades para consiga aprender vencer desafios o seu proporciona. Apesar da importância inclusão, ainda existem precisam vencidos formação adequada dos educadores estrutura física...
<title>Abstract</title> This correspondence marks the 10-year milestone of InsulinAPP, a Brazilian-developed electronic glycemic management system (eGMS) designed to support inpatient insulin therapy. Initially published in 2015, InsulinAPP was developed assist non-specialist physicians applying evidence-based protocols hospital settings. Over past decade, it has evolved into validated clinical decision-support tool with demonstrated impact across multiple care contexts. In this manuscript,...
The aim was to compare three ulcer classification systems as predictors of the outcome diabetic foot ulcers: Wagner, University Texas (UT) and size (area, depth), sepsis, arteriopathy, denervation system (S(AD)SAD) in a specialist clinic Brazil.Ulcer area, depth, appearance, infection associated ischaemia neuropathy were recorded consecutive series 94 subjects. A novel score, S(AD)SAD derived from sum individual items system, evaluated. Follow-up for at least 6 months. primary measure...
Lipodystrophy syndromes are rare disorders characterized by the selective loss of adipose tissue. We aimed to report a case acquired generalized lipodystrophy possibly associated with nivolumab. A woman was referred our Endocrinology Department for uncontrolled diabetes mellitus. At 50 years age, she diagnosed type 2 after routine laboratory test and her well controlled low doses metformin. In 2010, clear cell renal carcinoma. The cancer progressed in following years, leading initiation...
OBJECTIVE The prevalence of Nelson's syndrome has varied greatly, at least in part because the variability diagnostic criteria employed by different authors. We define as presence an enlarging pituitary tumour associated with elevated fasting plasma ACTH levels and hyperpigmentation patients Cushing's disease after bilateral adrenalectomy. have compared who developed adrenalectomy those did not. Our objective was to find differences between two groups which might predict development...
Abstract Background Maturity‐onset diabetes of the young (MODY) is a form monogenic with autosomal dominant inheritance. To date, mutations in 11 genes have been frequently associated this phenotype. In Brazil, few cohorts screened for MODY, all using candidate gene approach, high prevalence undiagnosed cases (MODY‐X). Methods We conducted next‐generation sequencing target panel (tNGS) study to investigate, first time, Brazilian cohort MODY patients negative prior genetic analysis. One...
To evaluate the circadian rhythms of plasma androstenedione (delta) and testosterone (T), we used continuous blood withdrawal at 30-min intervals for 24 h to obtain integrated concentrations in six normal men. The data were submitted contrast analysis as well a graphical method with smoothing variations between samples. As reference, cortisol (F) levels also measured, since they have defined rhythm. Integrated F had rhythm, highest 0500 0900 h, nadir values 2000 300 secretory peaks...
The aim of the present study was to evaluate prevention and self-inspection behavior diabetic subjects with foot at ulcer risk, no previous episode, who participated in routine visits standardized education provided by service received prescribed footwear. This evaluation carried out using a questionnaire scoring from 0-10 (high scores reflect worse practice compliance).60 patients were studied (30 each sex); mean age 62 years, duration disease 17 years. As for compliance, 90% showed total...
Abstract Background Oxidative stress is recognized as a major pathogenic factor of cellular damage caused by hyperglycemia. NOX/NADPH oxidases generate reactive oxygen species and NOX1, NOX2 NOX4 isoforms are expressed in kidney require association with subunit p22phox (encoded the CYBA gene). Increased expression was described animal models diabetic nephropathy. In opposite direction, glutathione one main endogenous antioxidants whose plasmatic concentrations were reported to be reduced...
To determine the characteristics of clinical care offered to type 1 diabetic patients across four distinct regions Brazil, with geographic and contrasting socioeconomic differences. Glycemic control, prevalence cardiovascular risk factors, screening for chronic complications frequency that recommended treatment goals were met using American Diabetes Association guidelines evaluated.This was a cross-sectional, multicenter study conducted from December 2008 2010 in 28 secondary tertiary public...
Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are autoimmune diseases have similar genetic patterns. T1DM treatment is based on diet, physical activity insulin therapy, whereas CD depends dietary changes with restriction of wheat, rye barley. The aim the study was to evaluate quality life (QoL) individuals association CD, characterize their nutritional status compare it those only one healthier controls.Sixty patients controlled by sex, age body mass index (BMI) were stratified...
Maturity-Onset Diabetes of the Young (MODY) type 4 or PDX1 -MODY is a rare form monogenic diabetes caused by heterozygous variants in . Pancreatic developmental anomalies related to are reported only neonatal cases. Here, we describe dorsal pancreatic agenesis 2 patients with -MODY. The proband presented since 14 years age and maintained regular glycemic control low doses basal insulin detectable C-peptide levels after 38 diabetes. A diagnosis MODY was suspected. Targeted next-generation...